High-Resolution Mapping Technique Uncovers Underlying Circuit Architecture of the Brain
Using an innovative brain-tracing technique, scientists have found a way to untangle the complex connections that influence specific brain functions.
University of California San Francisco
Give to UCSFUsing an innovative brain-tracing technique, scientists have found a way to untangle the complex connections that influence specific brain functions.
Results of a Phase III clinical trial showed that a simple drug regimen of two anti-clotting drugs lowered the risk of stroke by almost one-third, compared to aspirin alone, when given to patients who had minor or transient stroke symptoms to prevent subsequent attacks.
A UCSF-led research team has identified the likely genetic mechanism that causes some patients with multiple sclerosis to quickly progress to a debilitating stage of the disease while other patients progress much more slowly.
Gene mutations that lead to major birth defects may also cause subtle disruptions in the brain that contribute to psychiatric disorders such as schizophrenia, autism and bipolar disorder, according to new research by UCSF scientists.
Researchers at the Ernest Gallo Clinic and Research Center at UCSF have been able to identify and deactivate a brain pathway linked to memories that cause alcohol cravings in rats.
A new UCSF-led study looks at the close link between diabetes and dementia, which can create a vicious cycle.
UC San Francisco has launched a new app for the Apple iPad that presents a novel approach to learning the neurological physical exam, a challenging series of assessments aimed at diagnosing neurological disorders in patients.
A key type of human brain cell developed in the laboratory grows seamlessly when transplanted into the brains of mice, UCSF researchers have found.
Epilepsy that does not respond to drugs can be halted in adult mice by transplanting a specific type of cell into the brain, UCSF researchers have discovered, raising hope that a similar treatment might work in severe forms of human epilepsy.
Specific DNA once dismissed as junk plays an important role in brain development and might be involved in several devastating neurological diseases, UCSF scientists have found.
A Phase 2 clinical trial testing a new protocol for treating a relatively rare form of brain cancer, primary CNS lymphoma, may change the standard of care for this disease, according to UCSF doctors who led the research.
By stimulating one part of the brain with laser light, researchers at the National Institutes of Health and the Ernest Gallo Clinic and Research Center at UCSF have shown that they can wipe away addictive behavior in rats – or conversely turn non-addicted rats into compulsive cocaine seekers.
Electroencephalogram, which measures and records electrical activity in the brain, is a quick and efficient way of determining whether seizures are the cause of altered mental status and spells, according to a UCSF study.
<p>A team of researchers at UCSF has uncovered the neurological basis of speech motor control, the complex coordinated activity of tiny brain regions that controls our lips, jaw, tongue and larynx as we speak.</p>
Hospital MRIs may be better at predicting long-term outcomes for people with mild traumatic brain injuries than CT scans, according to a clinical trial led by researchers at UCSF and the San Francisco General Hospital and Trauma Center.
William Seeley maps the path of frontotemporal dementia through the brain, correlating specific damage with behavioral change. By studying the disease from self to circuits to cells, this visionary neurologist searches for inroads to treatment.
DNA sequences obtained from a handful of patients with multiple sclerosis at the UCSF Medical Center have revealed the existence of an “immune exchange” that allows the disease-causing cells to move in and out of the brain.
<p>UCSF neuroscientists have found that by training on attention tests, people young and old can improve brain performance and multitasking skills.</p>
<p>A new study that represents a significant first step in exploring the potential of stem cells to treat neurological disease is a “natural outgrowth” of a longstanding culture of interdisciplinary collaboration in UCSF neonatology — a culture that UCSF Benioff Children's Hospital physicians David Rowitch and Donna Ferriero work hard to sustain.</p>
<p><span>Research has shown that women are at greater risk of post-traumatic stress disorder (PTSD) than men. Now, scientists based at the UCSF-affiliated San Francisco Veterans Affairs Medical Center (SFVAMC) have found that women with the condition might be more likely to experience faster aging at the cellular level and increased risk for diseases of aging than men with PTSD.</span></p>
<p>There is no cure for multiple sclerosis, but several medications can help slow its devastating effects, and extend healthier years for the roughly 2.5 million people worldwide diagnosed with this chronic neurological disease.</p>
Scientists at the UCSF-affiliated Gladstone Institutes have discovered that an FDA-approved anti-epileptic drug reverses memory loss and alleviates other Alzheimer’s-related impairments in an animal model of the disease.
Raising levels of the neurotransmitter dopamine in the frontal cortex of the brain significantly decreased impulsivity in healthy adults, in a study conducted by researchers at the Ernest Gallo Clinic and Research Center at the University of California, San Francisco.