Induced Pluripotent Stem Cells: 10 Years After the Breakthrough
Ten years after Shinya Yamanaka published his Nobel Prize-winning discovery of induced pluripotent stem cells, there's been rapid progress in some areas and major challenges in others.
University of California San Francisco
Give to UCSFTen years after Shinya Yamanaka published his Nobel Prize-winning discovery of induced pluripotent stem cells, there's been rapid progress in some areas and major challenges in others.
Chronic pain and loss of bladder control are among the most devastating consequences of spinal cord injury.
A new study by UCSF researchers found that even moderate alcohol consumption may change the structure of the heart in ways that increase the risk of atrial fibrillation.
Joe DeRisi, co-director of the new Chan Zuckerberg Biohub at Mission Bay, speaks about his vision for the Biohub and what researchers can look forward to.
UCSF, Stanford and UC Berkeley will join forces in a new biomedical science research center funded by a $600 million commitment from Facebook CEO and founder Mark Zuckerberg and pediatrician Priscilla Chan.
A digital assessment platform designed to look and feel like a video game may successfully flag children with attention disorders.
Mothers who were raising children with autism and reported chronic stress were more likely to have high levels of “bad” cholesterol and lower levels of protective progenitor cells.
UCSF researchers have devised a new term, “sudden neurological death,” to describe apparent sudden cardiac deaths that actually were due to neurological causes.
Bruce Alberts and a group of prominent scientists have begun the Rescuing Biomedical Research initiative to fix what they see as systemic flaws in the current biomedical research enterprise.
A newly discovered cache of industry documents revealed that the sugar industry began working closely with nutrition scientists in the mid-1960s to single out fat and cholesterol as the dietary causes of coronary heart disease and to downplay evidence that sucrose consumption was also a risk factor.
Gut microbes present in some one-month-old infants predict a three-fold higher risk of developing allergic reactions by age two and asthma by age four.
UCSF's Resource Allocation Program, which offers a single online application process for a wide variety of intramural funding opportunities, is now inviting applications for the fall 2016 cycle.
A new UC San Francisco study challenges the most influential textbook explanation of how the mammalian brain detects when the body is becoming too warm, and how it then orchestrates the myriad responses that animals, including humans, use to lower their temperature.
Two hundred miles above Earth, NASA has conducted the first genome sequencing in space, and researchers at UCSF helped analyze the data sent back from the International Space Station and confirm that the sequencing was a success.
UCSF researchers studying beige fat – a calorie-burning tissue that can help to ward off obesity and diabetes – have discovered a new strategy to cultivate this beneficial blubber.
Early-stage breast cancer patients whose tumors carry genetic markers associated with a low risk of disease recurrence may not need to undergo chemotherapy, suggests a new study that employed a test devised by a UCSF researcher.
An interdisciplinary team of UCSF researchers, led by Xiao Hu, Michele Pelter and Richard Fidler from the UCSF School of Nursing, is working furiously to create and test a “super alarm.”
The ideal interval for breast cancer screening depends on combined assessments of each woman’s breast cancer risk and her breast density, according to a new study led by UCSF and University of Wisconsin researchers.
A new UCSF report on an understudied population – older homeless adults – reveals that adverse childhood experiences have long-lasting effects.
The number of Americans diagnosed with concussions is growing, most significantly in adolescents. UCSF researchers recommend that adolescents be prioritized for ongoing work in concussion education, diagnosis, treatment and prevention.
An international team of researchers has developed a new opioid drug candidate that blocks pain without triggering the dangerous side effects of current prescription painkillers.
A new UCSF-led study concludes that the price of a promising new class of cholesterol-lowering drugs would need to be reduced by up to 70 percent to be cost-effective.
The abundance of a subtype of white blood cells in melanoma tumors can predict whether or not patients will respond to a form of cancer immunotherapy known as checkpoint blockade, according to a new study led by UCSF researchers and physicians.
UC San Francisco’s Clinical and Translational Science Institute (CTSI) has received $85 million over five years from the National Institutes of Health (NIH) to continue to provide training, research support and other services, and to launch new programs aimed at diversifying the patients in research and advancing precision medicine.
The first results from a large international study of patients taking metformin, the world’s most commonly used type 2 diabetes drug, reveal genetic differences among patients that may explain why some respond much better to the drug than others.
A new analysis of nationwide emergency department (ED) records led by UC San Francisco researchers has revealed that black patients seen for back or abdominal pain are roughly half as likely as white patients to be prescribed opioids in the ED or at discharge.
A new study led by UCSF scientists shows that a bacterium commonly found in the human gut is overrepresented in patients with a rare, often disabling autoimmune disease known as neuromyelitis optica.
A new UCSF study shows that specialized brain cells in mice “predict” the hydrating effects of drinking, deactivating long before the liquids imbibed can actually change the composition of the bloodstream.
In a surprising finding, researchers at UC San Francisco have discovered that the prevalence among Americans of chronic kidney disease (CKD), a condition that costs Medicare tens of billions of dollars to treat each year, hasn't increased since the early 2000s.
One minute of exposure to second-hand smoke from marijuana diminishes blood vessel function to the same extent as tobacco, but the harmful cardiovascular effects last three times longer, according to a new study in rats led by UCSF researchers.