University of California San Francisco
Give to UCSFHospital MRIs may be better at predicting long-term outcomes for people with mild traumatic brain injuries than CT scans, according to a clinical trial led by researchers at UCSF and the San Francisco General Hospital and Trauma Center.
DNA sequences obtained from a handful of patients with multiple sclerosis at the UCSF Medical Center have revealed the existence of an “immune exchange” that allows the disease-causing cells to move in and out of the brain.
<p>A new study that represents a significant first step in exploring the potential of stem cells to treat neurological disease is a “natural outgrowth” of a longstanding culture of interdisciplinary collaboration in UCSF neonatology — a culture that UCSF Benioff Children's Hospital physicians David Rowitch and Donna Ferriero work hard to sustain.</p>
Scientists at the UCSF-affiliated Gladstone Institutes have discovered that an FDA-approved anti-epileptic drug reverses memory loss and alleviates other Alzheimer’s-related impairments in an animal model of the disease.
Scientists at the Gladstone Institutes have for the first time transformed skin cells — with a single genetic factor — into cells that develop on their own into an interconnected, functional network of brain cells.
Scientists at the Gladstone Institutes have unraveled a process by which depletion of a specific protein in the brain contributes to the memory problems associated with Alzheimer’s disease. These findings provide insights into the disease’s development and may lead to new therapies that could benefit the millions of people worldwide.
<p>The longstanding mystery of how selective hearing works — how people can tune in to a single speaker while tuning out their crowded, noisy environs — is solved this week in the journal <em>Nature</em> by two scientists from the University of California, San Francisco (UCSF).</p>
Scientists at the UCSF-affiliated Gladstone Institutes have enhanced the understanding of how a protein linked to Alzheimer’s disease keeps young brains healthy, but can damage them later in life — suggesting new research avenues for treating this devastating disease.
A new study raises hopes that physicians may be able to use MRI to predict the course of dementias and that researchers may use these predicted outcomes to determine whether a new treatment is working.
Neurologist Bruce Miller, MD, director of the UCSF Memory and Aging Center, participated in a roundtable discussion on Alzheimer’s disease and frontotemporal dementia on the "Charlie Rose Show."
Dogs with spinal cord injuries may soon benefit from an experimental drug being tested by researchers at UCSF and Texas A&M College of Veterinary Medicine & Biomedical Sciences — work that they hope will one day help people with similar injuries.
An experimental drug called Ocrelizumab has shown promise in a Phase 2 clinical trial involving 220 people with multiple sclerosis (MS), an often debilitating, chronic autoimmune disease that affects an increasing number of people in North America.
Patients diagnosed with traumatic brain injury (TBI) had over twice the risk of developing dementia within seven years after diagnosis compared to those without TBI, in a study of more than 280,000 older veterans conducted by researchers at the San Francisco VA Medical Center and UCSF.
<p>Each year, scores of soldiers wounded by explosives suffer from debilitating nerve injuries that render their arms and legs useless. Kim’s research, performed at the UCSF-affiliated San Francisco Veterans Affairs hospital, has led to development of artificial nerve grafts to accelerate healing of these injuries.</p>
<p>Many researchers are finding that by the time a patient seeks treatment for symptoms of Alzheimer’s disease, it’s often too late for the available drugs to have an effect. Boxer’s lab is studying very precise eye tracking methods to gauge mental fitness and identify cognitive decline decades before the first symptoms appear.</p>