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A clinical trial led by UC San Francisco has found that when pregnant women are educated about their choices on prenatal genetic testing, the number of tests actually drops, even when the tests are offered with no out-of-pocket costs.
Bacteria that normally live in and upon us have genetic blueprints that enable them to make thousands of molecules that act like drugs, and some of these molecules might serve as the basis for new human therapeutics, according to UCSF researchers.
Severe combined immunodeficiency (SCID), a potentially life-threatening, but treatable, disorder affecting infants, is twice as common as previously believed, according to a new study that is the first to examine the national impact of this newborn screening test.
UCSF researchers have identified cells’ unique features within the developing human brain, using the latest technologies for analyzing gene activity in individual cells, and have demonstrated that large-scale cell surveys can be done much more efficiently and cheaply than was previously thought possible.
A UCSF physician who treats birth defects affecting the face has teamed up with a European expert on animal evolution to create rodent teeth that harken back in evolutionary time.
The immune system ages and weakens with time, making the elderly prone to life-threatening infection and other maladies, and a UCSF research team now has discovered a reason why.
The popular idea that Northern Europeans developed light skin to absorb more UV light so they could make more vitamin D – vital for healthy bones and immune function – is questioned by UC San Francisco researchers in a new study.
In the most comprehensive study of the Mexican population to date, researchers from UCSF and Stanford University, along with Mexico’s National Institute of Genomic Medicine, have identified tremendous genetic diversity.
A team of researchers studying a flowering plant has zeroed in on the way cells manage external signals to adapt to prevailing conditions, a capability that is essential for cells to survive in a fluctuating environment.
Joshua Osborn was fighting for his life against a mysterious ailment. With his options dwindling, a team at UCSF employed advanced DNA sequencing technology to track down the culprit.
New genomic research led by UCSF scientists reveals that two common gene variants that lead to longer telomeres also significantly increase the risk of developing the deadly brain cancers known as gliomas.
A 14-year-old boy’s turnaround and quick recovery after mysteriously being stricken by brain-inflaming encephalitis shows that the newest generation of DNA analysis tools can be harnessed to reveal the cause of a life-threatening infection even when physicians have no suspects.
UCSF won gold and silver medals in an international contest from the Council for Advancement and Support of Education (CASE), which announced its Circle of Excellence awards Wednesday morning.
UCSF recently hosted a discussion at its Mission Bay campus about the topic of direct-to-consumer (DTC) genetic testing.
A scientific team led by the Gladstone Institutes and UCSF has discovered that a common form of a gene already associated with long life also improves learning and memory.
Four UCSF-affiliated researchers are among 102 recipients of the Presidential Early Career Awards for Scientists and Engineers.
Clinical Laboratories at UCSF Medical Center have entered into a partnership with UCLA to have their laboratories perform exome sequencing for inherited disorders on UCSF patients, effective April 14.
Genetic testing can help doctors choose the most effective and economical drugs to prevent blood clots in the half a million patients in the U.S. who receive coronary stents each year, according to a new study led by a UCSF researcher.
Scientists at the UCSF-affiliated Gladstone Institutes have found a way to efficiently edit the human genome one letter at a time, paving the way for therapies that cure disease.
Geneticists from Ohio, California and Japan used stem cells to correct a defective “ring chromosome” with a normal chromosome. Such therapy has the promise to correct chromosome abnormalities that give rise to birth defects, mental disabilities and growth limitations.
Experts across UCSF weigh in on what some of 2014's top trends are in research and patient care.
A team led by scientists from UCSF has discovered that recurrent gliomas may have genetic profiles that are markedly different from those of the initial tumors that spawned them.
The nation’s top scientists will gather at UCSF to discuss the latest in research discovery at a special symposium honoring the 2013 and 2014 Breakthrough Prize in Life Sciences Award recipients on Friday, Dec. 13.
The day after the 2014 Breakthrough Prize in Life Sciences winners are announced, the recipients – along with 2013 recipients, UCSF Nobel laureates and other luminaries in the field – will participate in a symposium on the state of research in cancer, genetics, neurobiology and stem cells.
Pamela Munster, MD, is program leader of Developmental Therapeutics at UCSF’s Helen Diller Family Comprehensive Cancer Center. She shares a breast cancer story here – her own.
UCSF’s Yuet Wai Kan, an internationally recognized leader in the field of human genetics, will be honored at the Personalized Medicine World Conference, PMWC 2014, to be held in January 2014 in Silicon Valley.
Precision Medicine Pillar No. 5: Omics Medicine. Molecular biologist Nevan Krogan's work is not only illuminating how genes and proteins function, it's also shedding light on the underlying biology of disease for each person.
Precision Medicine Pillar No. 4: Computational Health Sciences. Computationally intensive approaches are used to analyze and cross-analyze large but discrete collections of data, such as patient health histories and genetic makeup.
With inexpensive genetics kits flooding the market, both consumers — and their doctors — still lack basic information about what to do, if anything, with what they learn about their own genomes.
