Longevity Hormone is Lower in Stressed and Depressed Women
Women under chronic stress have significantly lower levels of klotho, a hormone that regulates aging and enhances cognition, researchers at UC San Francisco have found.
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University of California San Francisco
Give to UCSFWomen under chronic stress have significantly lower levels of klotho, a hormone that regulates aging and enhances cognition, researchers at UC San Francisco have found.
Preschoolers with oppositional defiant behavior are more likely to have shorter telomeres, a hallmark of cellular aging, which in adults is associated with increased risk for chronic diseases and conditions like diabetes, obesity and cancer.
A team of scientists has shown that using just three molecular markers will help clinicians classify gliomas – the most common type of malignant brain tumors – more accurately than current methods.
By studying fossilized teeth from thousands of extinct rodent species, UCSF and University of Helsinki scientists have shown how fundamental evolutionary mechanisms drive the emergence of novel mammalian stem cells.
A research team led by scientists from UCSF, Baylor College of Medicine, and Texas Children’s Hospital has identified a new autoimmune syndrome characterized by a combination of severe lung disease and arthritis that currently has no therapy.
Gov. Jerry Brown is launching a statewide initiative with the University of California to build the infrastructure and assemble the resources necessary to further develop precision medicine.
The evolution and development of structures as diverse as limbs, fingers, teeth, somites and vertebrae may have more in common than once believed, according to a new study.
A blood test undertaken between 10 to 14 weeks of pregnancy may be more effective in diagnosing Down syndrome and two other less common chromosomal abnormalities than standard non-invasive screening techniques.
A research team led by UCSF scientists has found the genetic signature of enterovirus D68 in half of the California and Colorado children diagnosed with acute flaccid myelitis – sudden, unexplained muscle weakness and paralysis – between 2012 and 2014.
A research team at UC San Francisco has discovered an RNA molecule called Pnky that can be manipulated to increase the production of neurons from neural stem cells.
A new study finds that the majority of those who seek treatment for Tourette syndrome will also be diagnosed with a second psychiatric disorder during their lifetimes, and often these disorders emerge earlier than in the general population
A team of UCSF and high school students won "Best Presentation" at the most recent international "Genetically Engineered Machine" competition, where engineering meets biology.
A team led by UCSF's John Fahy, MD, has discovered why mucus in the lungs of people with cystic fibrosis is thick, sticky and difficult to cough up, leaving these patients more vulnerable to lung infection.
Two dozen scientific papers published online simultaneously present the first comprehensive maps and analyses of the epigenomes of a wide array of human cell and tissue types.
A protein called YAP, which drives the growth of organs during development and regulates their size in adulthood, plays a key role in the emergence of resistance to targeted cancer therapies, according to a new study.
Meet the Tetrahymena, the pear-shaped protozoa that played a starring role in Nobel Prize-winning research about aging.
Genes are important, but diet may be even more important in determining the relative abundance of the hundreds of health-shaping bacterial species comprising an individual’s gut microbiota, according to UCSF scientists.
With advances in technology and better understanding of people, the health sciences are constantly pushing toward more effective treatments and cures. The question is, where will we see the next breakthroughs in 2015?
Researchers at UCSF have identified patterns of genetic activity that can be used to diagnose endometriosis and its severity.
Two major factors determine whether you get cancer – your genes and what you have been exposed to in the environment, says Allan Balmain, PhD, co-leader of UCSF’s Cancer Genetics Program.
A protein that may partly explain why human brains are larger than those of other animals has been identified by scientists from two stem-cell labs at UCSF.
UCSF is unveiling a comprehensive cancer genetic testing program integrated with patients' electronic medical records, a major milestone in bringing precision medicine into everyday practice.
UCSF has unveiled a new cloud-based software platform that significantly advances precision medicine for cancer.
Genetically engineering tumors in mice, a technique that has dominated cancer research for decades, may not replicate important features of cancers caused by exposure to environmental carcinogens, according to a new study led by UCSF scientists.
Two major genetic studies of autism, led in part by UCSF scientists and involving more than 50 laboratories worldwide, have newly implicated dozens of genes in the disorder.
Scores of autoimmune diseases mysteriously cause the immune system to harm tissues within our own bodies. Now, a new study pinpoints the complex genetic origins for many of these diseases.
A team of UCSF researchers has found that a tiny segment of genetic material known as a microRNA plays a central role in the transition from moderate drinking to alcohol use disorders.
An international research collaboration led by UCSF researchers has identified a genetic variant common in Latina women that protects against breast cancer.
The application of a new, precise way to turn genes on and off within cells is likely to lead to a better understanding of diseases and possibly to new therapies, according to UCSF scientists.