Recurrent Brain Cancers Follow Distinctive Genetic Paths
A team led by scientists from UCSF has discovered that recurrent gliomas may have genetic profiles that are markedly different from those of the initial tumors that spawned them.
University of California San Francisco
Give to UCSFA team led by scientists from UCSF has discovered that recurrent gliomas may have genetic profiles that are markedly different from those of the initial tumors that spawned them.
A new UCSF-led study of nearly 3,000 individuals links obesity to the development of kidney disease.
Taxing sugar-sweetened beverages is likely to decrease consumption, resulting in lower rates of diabetes and heart disease, and these health benefits are expected to be greatest for the low-income, Hispanic and African-American Californians who are at highest risk of diabetes, according to a new analysis led by researchers at UC San Francisco.
Women's reproductive health experts Diana Taylor and Tracy Weitz conducted the foundational research on the safety and quality of aspiration abortions that now has become law of the land in California.
Scientists at the UCSF-affiliated Gladstone Institutes have devised a new molecular sensor that can detect MS at its earliest stages, even before the onset of physical signs.
In a technical tour de force, UCSF scientists have determined, at near-atomic resolution, the structure of a protein that plays a central role in the perception of pain and heat.
In the first study of its kind, UCSF researchers found that youth using e-cigarettes were more likely to be trying to quit, but also were less likely to have stopped smoking and were smoking more, not less.
A UCSF investigator has won an eight-year grant from the National Cancer Institute for a major investigation into anal cancer, a debilitating and sometimes fatal disease largely concentrated among people with HIV.
The protein in cells that most often drives the development of cancers has eluded scientists’ efforts to block it for three decades — until now.
Current anti-obesity treatments include strategies to prevent food energy from being absorbed, such as orlistat, which prevents fat absorption from food.
Precision Medicine Pillar No. 2: Basic Discovery. The long path to developing potent new treatments often starts with an observation in the lab that then leads to a question about a fundamental life process.
Researchers at the UCSF-affiliated Gladstone Institutes have discovered how the activation of specific stretches of DNA control the development of uniquely human characteristics.
UCSF scientists were able to arrest, and even reverse, tissue scarring of the liver, kidneys and lungs in mice. The scarring, also known as fibrosis, is a major factor in nearly half of all deaths in developed countries.
When it comes to genes, a UCSF scientist wants to turn conventional wisdom about human and bacterial evolution on its head.
A UCSF-led team of scientists has discovered that a gene mutation found in some bladder cancers is indicative of low-risk tumors that are unlikely to recur or progress after surgery.
Through support from the Catalyst Awards, UCSF researcher Aditi Bhargava is working to develop a method for delivering small-molecules to a specific target group of cells for treatment of pain.
The way cells divide to form new cells – to support growth, to repair damaged tissues, or simply to maintain our healthy adult functioning – is controlled in previously unsuspected ways, UCSF researchers have discovered.
Childbirth is not a major contributor to sexual dysfunction in women later in life, according to a new study led by UCSF researchers.
Often deadly “triple-negative” breast cancers might be effectively treated in many cases with a drug that targets a previously unknown vulnerability in the tumors, UCSF reports.
UCSF researchers received six of 78 awards announced this week by the National Institutes of Health for innovative, high-risk, high-reward research.
A class of flame retardants that has been linked to learning difficulties in children has rapidly declined in pregnant women’s blood since the chemicals were banned in California a decade ago, according to a study led by researchers at UCSF.
UCSF will receive a five year, $20 million grant as part of a first-of-its-kind tobacco science regulatory program by the U.S. Food and Drug Administration and the National Institutes of Health.
A new link between meal times and daily changes in the immune system has been identified by UCSF researchers, and has led them to question assumptions about the roles of specific immune cells in infection and allergy.
Scientists from UCSF have identified a new way to manipulate the immune system that may keep it from attacking the body’s own molecules in autoimmune diseases such as type 1 diabetes, rheumatoid arthritis and multiple sclerosis.
A protein at the center of Parkinson’s disease research now also has been found to play a key role in causing the destruction of bacteria that cause tuberculosis.
A team of researchers at UCSF is incorporating genomics into a broad group of potential factors that can help clinicians better understand which patients are at greatest risk for persistent postsurgical pain and how to better prevent or treat it.
Quick changes in behavior, in worms, at least, can be triggered by a unique form of the molecule RNA acting within the nucleus of a cell, researchers at UCSF have discovered.
Mice given cocaine showed rapid growth in new brain structures associated with learning and memory, according to a research team from the Ernest Gallo Clinic and Research Center at UCSF.
Patients who participated in a smoking-cessation program during hospitalization for mental illness were able to quit smoking and were less likely to be hospitalized again for their psychiatric conditions.
UCSF scientists working in the lab used a chemical found in an anti-wrinkle cream to prevent the death of nerve cells damaged by mutations that cause an inherited form of Parkinson’s disease.