Bold Innovation Program Fast-Tracks Precision Medicine Research
Exciting advances in medicine and health are being researched in precision medicine projects recently funded by the George and Judy Marcus Program in Precision Medicine Innovation.
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University of California San Francisco
Give to UCSFExciting advances in medicine and health are being researched in precision medicine projects recently funded by the George and Judy Marcus Program in Precision Medicine Innovation.
With one drug to shut down its progression and another to undo its damage, plus a worldwide effort stalking the origins of multiple sclerosis, MS doesn’t stand a chance.
Frontotemporal dementia, the second most common cause of dementia in people under 65, may be triggered by a defect in immune cells called microglia that causes them to consume the brain’s synaptic connections, according to new research led by UCSF scientists.
In a study of 10 children published online in the American Journal of Human Genetics on April 14, the researchers linked a constellation of birth defects affecting the brain, eye, ear, heart and kidney to mutations in a single gene, called RERE.
Renowned UCSF immunologist Jeffrey Bluestone, PhD, has been named president and CEO of the Parker Institute for Cancer Immunotherapy, a national initiative launched with a $250 million grant from The Parker Foundation, established by Silicon Valley entrepreneur Sean Parker.
Scientists at UC San Francisco have been able to directly observe, for the first time, how invasive cancer cells create a beachhead as they migrate to the lung in a mouse model of metastatic cancer.
Research by UCSF scientists has opened up a surprising new avenue for potential therapies to reduce the risk of type 2 diabetes and other metabolic disorders that are associated with chronic tissue inflammation in obesity.
UCSF scientists have discovered a network of brain cells that allows animals to keep track of where they are when they are not moving through space, such as when they are eating, engaged in social interactions, or sleeping.
A newly discovered human gene mutation appears to contribute both to unusual sleep patterns and to heightened rates of seasonal depression, according to new research from UCSF.
Leading microbiome researchers recently came to UCSF to share the newest insights about how improving our relationship with our bodies’ microbial ecosystems could be the next big breakthrough in treating metabolic disease.
UCSF has received an unrestricted $25 million commitment from the Bill and Susan Oberndorf Foundation to advance basic research in psychiatry and the behavioral sciences.
A new study conducted at UCSF looked at “mid-level” marijuana users and found that this group had worse verbal memory but no deficiencies in other measures of cognitive function.
In the largest and longest study thus far of ethnic disparities in dementia risk, researchers compared six ethnic and racial groups within the same geographic population and found significant variation in dementia incidence among them.
You don't have to be an NFL star to throw better than any of our closest primate relatives. Human evolution has given us both the brain and brawn we need to make precise throws, but it comes with a few trade-offs.
UCSF scientists have created a new class of highly customizable biological sensors that can be used to form “logic gates” inside cells of the immune system, giving these cells the capability to home in on and kill a wide range of cancer cells while preventing them from attacking normal tissue.
A study of 35 families led by a UCSF psychiatric researcher showed for the first time that the structure of the brain circuitry known as the corticolimbic system is more likely to be passed down from mothers to daughters than from mothers to sons or from fathers to children of either gender.
Researchers at UCSF have found that boys and girls with sensory processing disorder (SPD) have altered pathways for brain connectivity when compared to typically developing children, and the difference predicts challenges with auditory and tactile processing.
The cells that create myelin, a fatty material that insulates nerve fibers in the brain’s white matter, migrate into the developing brain by climbing and swinging on blood vessels, according to new research led by UCSF scientists.
Children and young adults with severe forms of epilepsy that does not respond to standard antiepileptic drugs have fewer seizures when treated with purified cannabinoid, according to a multi-center study led by researchers from UCSF Benioff Children’s Hospital San Francisco.
The workings of neural circuits associated with creativity are significantly altered when artists are actively attempting to convey emotions, according to a new brain-scanning study of jazz pianists.
We asked experts across UCSF to identify what's ahead in how we approach research, what disease areas will see major advances, and where basic science will be translating into real treatments.
If depression is caused by flawed brain circuitry, it may be possible to shift that circuitry toward healthy neural processing instead. UCSF researchers hope to map and correct aberrant neural behavior to cure mood disorders.
In a bid to end the worst epidemic in modern times, the Foundation for AIDS Research (amfAR) is funding an ambitious effort based in San Francisco to eliminate the human immunodeficiency virus (HIV) from those who are infected.
In the first U.S. safety trial of a new form of immunotherapy for type 1 diabetes, patients experienced no serious adverse reactions after receiving infusions of as many as 2.6 billion cells that had been specially selected to protect the body’s ability to produce insulin.
A wave of specialized immune cells entering the skin in early life may induce tolerance to the hundreds of species of so-called friendly bacteria that live on the surface of the body.
A $10 million gift from The Parker Foundation, founded by Silicon Valley entrepreneur and philanthropist Sean Parker, will establish a new research laboratory within the UCSF Diabetes Center devoted to understanding autoimmunity.
The trajectory of Bruce Miller’s work is emblematic of the integration seen within the entire neurosciences field over the last decade, as its broad range of disciplines attract unprecedented levels of investment.
The Atlantic Philanthropies is awarding UCSF and Trinity College Dublin, the University of Dublin, $177 million to create the Global Brain Health Institute, a groundbreaking venture to stem the precipitous rise in dementia by training and connecting a new generation of leaders worldwide.
A gift of $20 million from the Ray and Dagmar Dolby Family Fund to the Department of Psychiatry at UCSF will support research on mood disorders.
To help stop the spread of antibiotic resistance, UCSF scientists are urging hospitals around the country to stop buying meat from animals that were given antibiotics for growth promotion.