Structure of Key Pain-Related Protein Unveiled
In a technical tour de force, UCSF scientists have determined, at near-atomic resolution, the structure of a protein that plays a central role in the perception of pain and heat.
University of California San Francisco
Give to UCSFIn a technical tour de force, UCSF scientists have determined, at near-atomic resolution, the structure of a protein that plays a central role in the perception of pain and heat.
Carlin Senter, MD, leader of UCSF’s concussion program, answers some frequently asked questions about this common brain injury.
A team led by UCSF scientists has identified the disruption of a single type of cell – in a particular brain region and at a particular time in brain development – as a significant factor in the emergence of autism.
Precision Medicine Pillar No. 3: Clinical Discovery. Researchers are taking vast amounts of patient data, often collected through first-ever clinical studies, and putting it into tools like MS Bioscreen that have a direct impact on patient care.
UCSF, a world-renowned center for the treatment of movement disorders, is holding an event to celebrate the program’s recognition by the Bachmann-Strauss Foundation as one of three new Centers of Excellence in the field.
Eleven leading scientists from the California Institute for Quantitative Biosciences (QB3) presented their latest aging research findings and anti-aging strategies at a daylong symposium called “The Science of Staying Younger Longer.”
New research by scientists at UC San Francisco shows that one of the brain’s fundamental self-protection mechanisms depends on coordinated, finely calibrated teamwork among neurons and non-neural cells.
Through support from the Catalyst Awards, UCSF researcher Aditi Bhargava is working to develop a method for delivering small-molecules to a specific target group of cells for treatment of pain.
Scientists at UCSF are reporting that they have found a way to reverse some of the negative effects of aging on the brain, using a video game designed to improve cognitive control.
A protein at the center of Parkinson’s disease research now also has been found to play a key role in causing the destruction of bacteria that cause tuberculosis.
An antihistamine discovered in the 1950s to treat itching may also prevent seizures in an intractable form of childhood epilepsy, according to researchers at UC San Francisco who tested it in zebrafish bred to mimic the disease.
Quick changes in behavior, in worms, at least, can be triggered by a unique form of the molecule RNA acting within the nucleus of a cell, researchers at UCSF have discovered.
Mice given cocaine showed rapid growth in new brain structures associated with learning and memory, according to a research team from the Ernest Gallo Clinic and Research Center at UCSF.
UCSF scientists working in the lab used a chemical found in an anti-wrinkle cream to prevent the death of nerve cells damaged by mutations that cause an inherited form of Parkinson’s disease.
An international study on epilepsy has uncovered 25 new mutations on nine key genes that could pave the way to develop precise therapies for a devastating form of the disorder during childhood.
UCSF researchers have developed a two-minute assessment tool to help hospital staff predict a patient’s risk of delirium, a change in mental cognition characterized by severe confusion and disorientation that can prolong hospital stays.
Anemia, or low levels of red blood cells, may increase the risk of dementia, according to a new UCSF-led study that found people who were anemic had a nearly 41 percent higher risk of developing the condition than those who were not.
A research team led by scientists from the Ernest Gallo Clinic and Research Center at UCSF has identified circuitry in the brain that drives compulsive drinking in rats, and likely plays a similar role in humans.
Scientists at the UCSF-affiliated Gladstone Institutes have discovered that the progression of neurodegenerative disease is not due to the buildup of brain toxins itself, but rather in the individual neurons’ ability to dissolve them.
A new UCSF research project is exploring whether singing in a community choir can provide tangible health advantages to older adults.
Sensory processing disorders are more prevalent in children than autism. In a groundbreaking new study, UCSF researchers have for the first time shown a biological basis for the disease in the brain structure.
UCSF scientists discussed their work in developing software, apps and online tools to help veterans with PTSD and brain injuries at the annual "Brain at War" symposium.
Using an innovative brain-tracing technique, scientists have found a way to untangle the complex connections that influence specific brain functions.
A UCSF-led team has discovered a sensory system in the foreleg of the male fruit fly that answers a central problem in evolution that is poorly understood: how animals of one species know not to mate with animals of other species.
Results of a Phase III clinical trial showed that a simple drug regimen of two anti-clotting drugs lowered the risk of stroke by almost one-third, compared to aspirin alone, when given to patients who had minor or transient stroke symptoms to prevent subsequent attacks.
A UCSF-led research team has identified the likely genetic mechanism that causes some patients with multiple sclerosis to quickly progress to a debilitating stage of the disease while other patients progress much more slowly.
Gene mutations that lead to major birth defects may also cause subtle disruptions in the brain that contribute to psychiatric disorders such as schizophrenia, autism and bipolar disorder, according to new research by UCSF scientists.
Researchers at the Ernest Gallo Clinic and Research Center at UCSF have been able to identify and deactivate a brain pathway linked to memories that cause alcohol cravings in rats.