Sustainable Science to Promote Health in Africa
Over more than two decades in Africa, UCSF researchers have approached their scientific work with a dual aim: treat disease while helping to sustainably build up the local health care system.
University of California San Francisco
Give to UCSFOver more than two decades in Africa, UCSF researchers have approached their scientific work with a dual aim: treat disease while helping to sustainably build up the local health care system.
A UCSF investigator has won an eight-year grant from the National Cancer Institute for a major investigation into anal cancer, a debilitating and sometimes fatal disease largely concentrated among people with HIV.
The protein in cells that most often drives the development of cancers has eluded scientists’ efforts to block it for three decades — until now.
Current anti-obesity treatments include strategies to prevent food energy from being absorbed, such as orlistat, which prevents fat absorption from food.
Precision Medicine Pillar No. 2: Basic Discovery. The long path to developing potent new treatments often starts with an observation in the lab that then leads to a question about a fundamental life process.
With inexpensive genetics kits flooding the market, both consumers — and their doctors — still lack basic information about what to do, if anything, with what they learn about their own genomes.
Researchers at the UCSF-affiliated Gladstone Institutes have discovered how the activation of specific stretches of DNA control the development of uniquely human characteristics.
UCSF scientists were able to arrest, and even reverse, tissue scarring of the liver, kidneys and lungs in mice. The scarring, also known as fibrosis, is a major factor in nearly half of all deaths in developed countries.
When it comes to genes, a UCSF scientist wants to turn conventional wisdom about human and bacterial evolution on its head.
A UCSF-led team of scientists has discovered that a gene mutation found in some bladder cancers is indicative of low-risk tumors that are unlikely to recur or progress after surgery.
Through support from the Catalyst Awards, UCSF researcher Aditi Bhargava is working to develop a method for delivering small-molecules to a specific target group of cells for treatment of pain.
A team of UCSF researchers developing cell-based therapies for acute respiratory distress syndrome benefited from advisors who helped identify gaps in their development plan.
The way cells divide to form new cells – to support growth, to repair damaged tissues, or simply to maintain our healthy adult functioning – is controlled in previously unsuspected ways, UCSF researchers have discovered.
UCSF researchers received six of 78 awards announced this week by the National Institutes of Health for innovative, high-risk, high-reward research.
The report earlier this year of a new hepatitis virus was a false alarm, according to UCSF researchers who correctly identified the virus as a contaminant present in a type of glassware used in many research labs.
Some of UCSF’s leading experts discuss the potential impact of new health care coverage options on hospitals and clinics, and on women and children, available statewide under the Affordable Care Act (ACA).
Janet Coffman, an expert on evidence-based medicine and health insurance coverage especially as it relates to prevention and California, discusses the impact of the Affordable Care Act and health exchanges on the state.
A class of flame retardants that has been linked to learning difficulties in children has rapidly declined in pregnant women’s blood since the chemicals were banned in California a decade ago, according to a study led by researchers at UCSF.
UCSF will receive a five year, $20 million grant as part of a first-of-its-kind tobacco science regulatory program by the U.S. Food and Drug Administration and the National Institutes of Health.
More adults in California are flocking to emergency rooms, especially those on Medicaid who are using ERs at a faster rate than the uninsured or privately insured, according to new UCSF research.
A new link between meal times and daily changes in the immune system has been identified by UCSF researchers, and has led them to question assumptions about the roles of specific immune cells in infection and allergy.
A protein at the center of Parkinson’s disease research now also has been found to play a key role in causing the destruction of bacteria that cause tuberculosis.
Quick changes in behavior, in worms, at least, can be triggered by a unique form of the molecule RNA acting within the nucleus of a cell, researchers at UCSF have discovered.
A team led by UCSF researchers has called for simplified guidelines on when to biopsy thyroid nodules for cancer, which they say would result in fewer unnecessary biopsies.
UCSF scientists working in the lab used a chemical found in an anti-wrinkle cream to prevent the death of nerve cells damaged by mutations that cause an inherited form of Parkinson’s disease.
A natural form of sugar could offer a noninvasive way to precisely image tumors and determine whether cancer medication is effective using new technology developed at UCSF in collaboration with GE Healthcare.
Researchers have probed deep into the cell’s genome to begin learning the “grammar” that helps determine whether or not a gene gets switched on to make the protein it encodes, advancing efforts to use gene and cell-based therapies to treat disease.
UCSF’s Emmanuelle Passegué, an expert on how the blood system arises during development, recently led a study in which researchers discovered how leukemia, a blood cancer, can gain a stronghold in bone marrow and inhibit the development of normal immune cells.
A team of investigators led by UCSF and the Gladstone Institutes has found a way to map an enzyme’s underlying molecular machinery, revealing patterns that could allow them to predict how an enzyme behaves – and what happens when this process disrupted.
Commercial casinos are often exempt from smoke-free workplace laws, but a new study led by UCSF has found that when smoking is banned in casinos, it results in considerably fewer emergency calls for ambulances.