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Bacteria that normally live in and upon us have genetic blueprints that enable them to make thousands of molecules that act like drugs, and some of these molecules might serve as the basis for new human therapeutics, according to UCSF researchers.
Severe combined immunodeficiency (SCID), a potentially life-threatening, but treatable, disorder affecting infants, is twice as common as previously believed, according to a new study that is the first to examine the national impact of this newborn screening test.
UCSF researchers have identified cells’ unique features within the developing human brain, using the latest technologies for analyzing gene activity in individual cells, and have demonstrated that large-scale cell surveys can be done much more efficiently and cheaply than was previously thought possible.
A UCSF physician who treats birth defects affecting the face has teamed up with a European expert on animal evolution to create rodent teeth that harken back in evolutionary time.
The immune system ages and weakens with time, making the elderly prone to life-threatening infection and other maladies, and a UCSF research team now has discovered a reason why.
The popular idea that Northern Europeans developed light skin to absorb more UV light so they could make more vitamin D – vital for healthy bones and immune function – is questioned by UC San Francisco researchers in a new study.
In the most comprehensive study of the Mexican population to date, researchers from UCSF and Stanford University, along with Mexico’s National Institute of Genomic Medicine, have identified tremendous genetic diversity.
A team of researchers studying a flowering plant has zeroed in on the way cells manage external signals to adapt to prevailing conditions, a capability that is essential for cells to survive in a fluctuating environment.
Joshua Osborn was fighting for his life against a mysterious ailment. With his options dwindling, a team at UCSF employed advanced DNA sequencing technology to track down the culprit.
New genomic research led by UCSF scientists reveals that two common gene variants that lead to longer telomeres also significantly increase the risk of developing the deadly brain cancers known as gliomas.
A 14-year-old boy’s turnaround and quick recovery after mysteriously being stricken by brain-inflaming encephalitis shows that the newest generation of DNA analysis tools can be harnessed to reveal the cause of a life-threatening infection even when physicians have no suspects.
From prostate cancer to immunotherapy to genetic testing, UCSF research is providing new insights and aiding in the development of new treatment strategies for cancer.
A scientific team led by the Gladstone Institutes and UCSF has discovered that a common form of a gene already associated with long life also improves learning and memory.
Nobel Prize winner Stanley Prusiner is closing in on better treatments for Alzheimer's, Parkinson's and other brain diseases, and an unlikely new partnership will get him there faster.
Four UCSF-affiliated researchers are among 102 recipients of the Presidential Early Career Awards for Scientists and Engineers.
