Archive: High-Resolution Mapping Technique Uncovers Underlying Circuit Architecture of the Brain
Using an innovative brain-tracing technique, scientists have found a way to untangle the complex connections that influence specific brain functions.
University of California San Francisco
Give to UCSFUsing an innovative brain-tracing technique, scientists have found a way to untangle the complex connections that influence specific brain functions.
A UCSF-led research team has identified the likely genetic mechanism that causes some patients with multiple sclerosis to quickly progress to a debilitating stage of the disease while other patients progress much more slowly.
Gene mutations that lead to major birth defects may also cause subtle disruptions in the brain that contribute to psychiatric disorders such as schizophrenia, autism and bipolar disorder, according to new research by UCSF scientists.
Researchers at the UCSF-affiliated Gladstone Institutes have discovered how one important protein falls under direct instructions from the body’s circadian clock and how this protein regulates fundamental circadian processes.
Scientists at the Gladstone Institutes have deciphered how a protein called Arc regulates the activity of neurons – providing much-needed clues into the brain’s ability to form long-lasting memories.
A new application of an existing medical imaging technology could help predict long-term damage in patients with traumatic brain injury, according to a recent UCSF study.
A key type of human brain cell developed in the laboratory grows seamlessly when transplanted into the brains of mice, UCSF researchers have found.
Epilepsy that does not respond to drugs can be halted in adult mice by transplanting a specific type of cell into the brain, UCSF researchers have discovered, raising hope that a similar treatment might work in severe forms of human epilepsy.
A UCSF-led research team has identified a genetic mutation that is strongly associated with a typical form of migraine. The discovery could lead to more effective therapies for people with this condition.
A Phase 2 clinical trial testing a new protocol for treating a relatively rare form of brain cancer, primary CNS lymphoma, may change the standard of care for this disease, according to UCSF doctors who led the research.
UCSF has recently partnered with Lawrence Berkeley National Laboratory and UC Berkeley to form the Tri-Institutional Partnership, in an effort to promote collaborative research among the three institutions.
President Barack Obama has unveiled a bold public-private initiative to map the brain to gain greater insight on how we think, learn and remember and to better understand and treat diseases ranging from autism to schizophrenia.
Scientists at the UCSF-affiliated Gladstone Institutes have discovered that a certain type of DNA damage long thought to be particularly detrimental to brain cells can actually be part of a regular, non-harmful process.
Electroencephalogram, which measures and records electrical activity in the brain, is a quick and efficient way of determining whether seizures are the cause of altered mental status and spells, according to a UCSF study.
Scientists at UCSF have discovered how memory recall is linked to decision-making in rats, showing that measurable activity in one part of the brain occurs when rats in a maze are playing out memories that help them decide which way to turn.
Researchers have mapped the three-dimensional global connections within the brains of seven adults, which reveal new details about the condition known as agenesis of the corpus callosum, one of the top genetic causes of autism.
<p>A team of researchers at UCSF has uncovered the neurological basis of speech motor control, the complex coordinated activity of tiny brain regions that controls our lips, jaw, tongue and larynx as we speak.</p>
William Seeley maps the path of frontotemporal dementia through the brain, correlating specific damage with behavioral change. By studying the disease from self to circuits to cells, this visionary neurologist searches for inroads to treatment.
Decreasing the level of a key brain protein led to significantly less drinking and alcohol-seeking behavior in rats and mice that had been trained to drink, according to a study by researchers at the Ernest Gallo Clinic and Research Center at UCSF.
<p>UCSF neuroscientists have found that by training on attention tests, people young and old can improve brain performance and multitasking skills.</p>
<p>Biomedical researchers at UCSF have won five of 51 prestigious National Institutes of Health Director’s New Innovator awards for high-risk, high-reward research, each receiving up to $1.5 million over five years.</p>
<p><span>Research has shown that women are at greater risk of post-traumatic stress disorder (PTSD) than men. Now, scientists based at the UCSF-affiliated San Francisco Veterans Affairs Medical Center (SFVAMC) have found that women with the condition might be more likely to experience faster aging at the cellular level and increased risk for diseases of aging than men with PTSD.</span></p>
Scientists at the UCSF-affiliated Gladstone Institutes have discovered that an FDA-approved anti-epileptic drug reverses memory loss and alleviates other Alzheimer’s-related impairments in an animal model of the disease.