University of California San Francisco
Give to UCSFScientists at the UCSF-affiliated Gladstone Institutes have discovered that the progression of neurodegenerative disease is not due to the buildup of brain toxins itself, but rather in the individual neurons’ ability to dissolve them.
Sensory processing disorders are more prevalent in children than autism. In a groundbreaking new study, UCSF researchers have for the first time shown a biological basis for the disease in the brain structure.
UCSF scientists discussed their work in developing software, apps and online tools to help veterans with PTSD and brain injuries at the annual "Brain at War" symposium.
A UCSF-led team has discovered a sensory system in the foreleg of the male fruit fly that answers a central problem in evolution that is poorly understood: how animals of one species know not to mate with animals of other species.
Using an innovative brain-tracing technique, scientists have found a way to untangle the complex connections that influence specific brain functions.
A UCSF-led research team has identified the likely genetic mechanism that causes some patients with multiple sclerosis to quickly progress to a debilitating stage of the disease while other patients progress much more slowly.
Gene mutations that lead to major birth defects may also cause subtle disruptions in the brain that contribute to psychiatric disorders such as schizophrenia, autism and bipolar disorder, according to new research by UCSF scientists.
Researchers at the UCSF-affiliated Gladstone Institutes have discovered how one important protein falls under direct instructions from the body’s circadian clock and how this protein regulates fundamental circadian processes.
Scientists at the Gladstone Institutes have deciphered how a protein called Arc regulates the activity of neurons – providing much-needed clues into the brain’s ability to form long-lasting memories.
A new application of an existing medical imaging technology could help predict long-term damage in patients with traumatic brain injury, according to a recent UCSF study.
A key type of human brain cell developed in the laboratory grows seamlessly when transplanted into the brains of mice, UCSF researchers have found.
Epilepsy that does not respond to drugs can be halted in adult mice by transplanting a specific type of cell into the brain, UCSF researchers have discovered, raising hope that a similar treatment might work in severe forms of human epilepsy.
A UCSF-led research team has identified a genetic mutation that is strongly associated with a typical form of migraine. The discovery could lead to more effective therapies for people with this condition.
A Phase 2 clinical trial testing a new protocol for treating a relatively rare form of brain cancer, primary CNS lymphoma, may change the standard of care for this disease, according to UCSF doctors who led the research.
UCSF has recently partnered with Lawrence Berkeley National Laboratory and UC Berkeley to form the Tri-Institutional Partnership, in an effort to promote collaborative research among the three institutions.
President Barack Obama has unveiled a bold public-private initiative to map the brain to gain greater insight on how we think, learn and remember and to better understand and treat diseases ranging from autism to schizophrenia.
Scientists at the UCSF-affiliated Gladstone Institutes have discovered that a certain type of DNA damage long thought to be particularly detrimental to brain cells can actually be part of a regular, non-harmful process.
Electroencephalogram, which measures and records electrical activity in the brain, is a quick and efficient way of determining whether seizures are the cause of altered mental status and spells, according to a UCSF study.
Scientists at UCSF have discovered how memory recall is linked to decision-making in rats, showing that measurable activity in one part of the brain occurs when rats in a maze are playing out memories that help them decide which way to turn.
Researchers have mapped the three-dimensional global connections within the brains of seven adults, which reveal new details about the condition known as agenesis of the corpus callosum, one of the top genetic causes of autism.