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The abundance of a subtype of white blood cells in melanoma tumors can predict whether or not patients will respond to a form of cancer immunotherapy known as checkpoint blockade, according to a new study led by UCSF researchers and physicians.
UC San Francisco’s Clinical and Translational Science Institute (CTSI) has received $85 million over five years from the National Institutes of Health (NIH) to continue to provide training, research support and other services, and to launch new programs aimed at diversifying the patients in research and advancing precision medicine.
A new analysis of nationwide emergency department (ED) records led by UC San Francisco researchers has revealed that black patients seen for back or abdominal pain are roughly half as likely as white patients to be prescribed opioids in the ED or at discharge.
The first results from a large international study of patients taking metformin, the world’s most commonly used type 2 diabetes drug, reveal genetic differences among patients that may explain why some respond much better to the drug than others.
A new study led by UCSF scientists shows that a bacterium commonly found in the human gut is overrepresented in patients with a rare, often disabling autoimmune disease known as neuromyelitis optica.
A new UCSF study shows that specialized brain cells in mice “predict” the hydrating effects of drinking, deactivating long before the liquids imbibed can actually change the composition of the bloodstream.
In a surprising finding, researchers at UC San Francisco have discovered that the prevalence among Americans of chronic kidney disease (CKD), a condition that costs Medicare tens of billions of dollars to treat each year, hasn't increased since the early 2000s.
One minute of exposure to second-hand smoke from marijuana diminishes blood vessel function to the same extent as tobacco, but the harmful cardiovascular effects last three times longer, according to a new study in rats led by UCSF researchers.
With two projects already underway to find new therapies for children with difficult-to-treat cancer and to help doctors diagnose hospitalized patients with acute infections, the California Initiative to Advance Precision Medicine (CIAPM) is announcing a new round of funding open to a wider range of applicants.
Infants who are exclusively breastfed early in life are more likely by age 4 or 5 to have longer telomeres, the protective bits of DNA that cap the ends of chromosomes in cells.
A serious childhood cancer takes advantage of a quality control mechanism that usually protects cells from stress-induced damage to propel tumor growth, according to a new study led by researchers at UC San Francisco and the University of Pittsburgh.
Reducing sugar consumption in obese children, rather than cutting calories or starch, or losing weight, leads to a sharp decline in triglycerides and a key protein called ApoC-III – two features that are associated with heart disease in adulthood.
Zika virus can infect numerous cell types in the human placenta and amniotic sac, according to researchers at UCSF and UC Berkeley who show in a new paper how the virus travels from a pregnant woman to her fetus.
A new UCSF study of top-rated mobile health apps showed that they offer little help to vulnerable patients – those who might benefit the most from these tools.
Using advanced imaging technology that allowed them to spy on interactions among cells in the lymph nodes of living mice, a research team led by UCSF scientists has identified a cell that is a key player in mounting the immune system’s defense against cancer.
Symptoms of infection with the Zika virus in Brazil may be masked by simultaneous infection with other mosquito-spread viruses common in the same region — such as dengue fever and chikungunya viruses — pointing to the need for comprehensive testing, according to a study led by a UCSF expert in DNA-based diagnostics in collaboration with Brazilian researchers.
A new study led by UCSF researchers found that women whose first child was born at 37 to 38 weeks – so-called “early-term” birth – are two to three times more likely to experience preterm birth, defined as birth at a gestational age less than 37 weeks, when giving birth to a second child.
Spurred by three decades of momentum and fresh funding, UCSF scientists mount a major effort to finally defeat AIDS.
A previously unidentifiable type of low-grade inflammation may explain why common anti-inflammatory drugs such as aspirin have shown promise against some types of cancer – even when patients don’t display typical signs of inflammation.
School children drink more water if the traditional water fountain is replaced by a dispenser with cups, according to findings of a study led by researchers at UCSF.
Lending support to the idea that high-calorie diets, sedentariness and other aspects of the contemporary American lifestyle may be driving the obesity epidemic, UCSF researchers have found that people who carry greater genetic risk for obesity were more likely to have a higher body mass index if they were born later in the 20th century.
Taking patients’ risk of developing dental caries (“cavities”) into account can help dentists effectively tailor individual prevention and treatment efforts, according to a recent study led by researchers from the UCSF School of Dentistry.
The board of directors for UCSF Benioff Children’s Hospitals has recently expanded to reflect the growing reach and impact of the children’s enterprise.
More women these days are grooming their pubic hair, especially younger women, but the practice poses some risks, most often related to shaving injuries.
A drug commonly used to treat high blood pressure has been shown to significantly reduce the risk of blocked electrical impulses to the heart and could be an effective treatment for certain types of heart disease known as conduction disease, in which the progression of electrical impulses through the heart is impeded.
Measuring the levels of a small number of proteins in the blood of patients with coronary heart disease may eventually allow doctors to more reliably assess the risk of future heart attacks, heart failure, strokes, and death in these patients, according to new research led by a UCSF cardiologist.
More than one in three atrial fibrillation (AF) patients at intermediate to high risk for stroke were treated with aspirin alone, despite previous data showing this therapy to be inferior to blood thinners, according to researchers at the UC San Diego and UCSF schools of medicine.
When doctors accept meals from pharmaceutical salespeople, they are much more likely to prescribe the drugs the representatives are promoting than cheaper generic alternatives, UCSF researchers found .
A new study from Marquette University and UC San Francisco has found that researchers are not reporting sexual orientation and transgender identities in psychotherapy outcome studies for anxiety and depression, which the authors say poses significant challenges for determining whether or not these treatments work for LGBT people.