University of California San Francisco
Give to UCSFScientists at UCSF have found a more precise way to turn off genes, a finding that will speed research discoveries and biotech advances and may eventually prove useful in reprogramming cells to regenerate organs and tissues.
<p>UCSF researchers have discovered a molecular machine that helps protect a cell’s genes against invading DNA that contributes to inherited human disease and death.</p>
People with the shortest telomeres really do have a date with the Grim Reaper, according to new data coming out of the largest and most diverse genomics, health and longevity project in the nation.
DNA sequences obtained from a handful of patients with multiple sclerosis at the UCSF Medical Center have revealed the existence of an “immune exchange” that allows the disease-causing cells to move in and out of the brain.
<p>Personalized medicine advances arising from genetic discoveries were the primary focus of wide-ranging presentations at the <a href="http://humgen.medschool.ucsf.edu/">UCSF Institute for Human Genetics</a> 2012 Symposium on Nov. 5.</p>
As Californians prepare to vote on Proposition 37, which would require labeling of food that’s been genetically modified, debate continues on the health implications of eating such foods.
Electronic health records (EHRs) are used widely by California physicians, but many of their systems are not designed to meet new federal standards aimed at improving the quality of health care, according to a report from UCSF researchers.
In November 2011, a National Academy of Sciences committee issued a report calling for the creation of a “Google Maps”-like data network intended to revolutionize medical discovery, diagnosis and treatment. Today, the co-chair of that committee, UCSF Chancellor Susan Desmond-Hellmann, MD, MPH, is issuing a call-to-arms to patient advocates to help make that idea a reality.
Hormones shape our bodies, make us fertile, excite our most basic urges, and as scientists have known for years, they govern the behaviors that separate men from women. But how?
<p>A cure for sickle cell anemia and other life-threatening genetic disorders that arise in the blood is the goal of a new $6.7-million, five-year research project headed by UCSF scientist Y. W. Kan, a pioneer of modern genetics and the diagnosis of genetic diseases before birth.</p>
<p>A National Academy of Sciences committee co-chaired by UCSF Chancellor Susan Desmond-Hellmann, MD, MPH, recommends the creation of a Google maps-like data network that could transform the future of medical discovery, diagnosis and treatment.</p>
<p>Microbes that dwell within us can help or harm us, according to UCSF experts at "Gut Check," a lunchtime panel discussion hosted by UCSF as part of the Bay Area Science Festival last week.</p>
<p>Personalized medicine and new gene discoveries in human disease were a focus of a daylong symposium hosted by the UCSF Institute for Human Genetics on the Mission Bay campus on Oct. 3.</p>
<p>A consortium of scientists is reporting that genetic secrets of multiple sclerosis may be buried in 50 “hot spots” in the human genome, a finding that will guide future efforts to assess an individual’s risk of susceptibility and may help develop new drugs for treating this complex disease.</p>
Molecular biologist Elizabeth H. Blackburn, PhD, 60, of the University of California, San Francisco, received the 2009 Nobel Prize in Physiology or Medicine on December 10th, 2009 in Stockholm, Sweden.
Telomeres — which are the DNA repeats that form the tips of chromosomes and are produced by the telomerase enzyme — play a crucial, and curious, role in the life of the cell.
Scientists have discovered the first gene involved in regulating the optimal length of human sleep, offering a window into a key aspect of slumber, an enigmatic phenomenon that is critical to human physical and mental health
Narcolepsy, a sleep disorder that can cause sufferers to suddenly lose muscle tone and start dreaming, is an autoimmune disease, a team led by UCSF and Stanford scientists finds.
The earliest-rising morning larks and the most extreme night owls may have a reason to blame genes — sometimes just one gene -- for their being out of sync with the rest of us.
A new finding may open the way to developing drugs to prevent or reverse potentially deadly insulin resistance syndrome.