Joe DeRisi on How the Biohub Will Create Opportunities for Research Collaboration
Joe DeRisi, co-director of the new Chan Zuckerberg Biohub at Mission Bay, speaks about his vision for the Biohub and what researchers can look forward to.
University of California San Francisco
Give to UCSFJoe DeRisi, co-director of the new Chan Zuckerberg Biohub at Mission Bay, speaks about his vision for the Biohub and what researchers can look forward to.
UCSF, Stanford and UC Berkeley will join forces in a new biomedical science research center funded by a $600 million commitment from Facebook CEO and founder Mark Zuckerberg and pediatrician Priscilla Chan.
Gut microbes present in some one-month-old infants predict a three-fold higher risk of developing allergic reactions by age two and asthma by age four.
Two hundred miles above Earth, NASA has conducted the first genome sequencing in space, and researchers at UCSF helped analyze the data sent back from the International Space Station and confirm that the sequencing was a success.
Early-stage breast cancer patients whose tumors carry genetic markers associated with a low risk of disease recurrence may not need to undergo chemotherapy, suggests a new study that employed a test devised by a UCSF researcher.
The first results from a large international study of patients taking metformin, the world’s most commonly used type 2 diabetes drug, reveal genetic differences among patients that may explain why some respond much better to the drug than others.
Infants who are exclusively breastfed early in life are more likely by age 4 or 5 to have longer telomeres, the protective bits of DNA that cap the ends of chromosomes in cells.
Symptoms of infection with the Zika virus in Brazil may be masked by simultaneous infection with other mosquito-spread viruses common in the same region — such as dengue fever and chikungunya viruses — pointing to the need for comprehensive testing, according to a study led by a UCSF expert in DNA-based diagnostics in collaboration with Brazilian researchers.
A previously unidentifiable type of low-grade inflammation may explain why common anti-inflammatory drugs such as aspirin have shown promise against some types of cancer – even when patients don’t display typical signs of inflammation.
Lending support to the idea that high-calorie diets, sedentariness and other aspects of the contemporary American lifestyle may be driving the obesity epidemic, UCSF researchers have found that people who carry greater genetic risk for obesity were more likely to have a higher body mass index if they were born later in the 20th century.
Esteban G. Burchard has become a leading national voice for increasing diversity in the biomedical research workforce, which he sees as deeply tied to racial inequalities in health care.
DeRisi, chair of the Department of Biochemistry and Biophysics at UCSF, has been elected to the National Academy of Sciences, one of the highest honors accorded to an American scientist.
Researchers at UC San Francisco and Stanford University have performed the first comprehensive survey of the central genes and proteins essential to bacterial life.
Results from the largest single study of the genetic and environmental causes of asthma in African-American children suggest that only a tiny fraction of known genetic risk factors for the disease apply to this population, raising concerns for clinicians and scientists working to stem the asthma epidemic among African-Americans.
UCSF is starting a campus-wide bioethics program led by the noted bioethics scholar Barbara Koenig to ensure that the rapid advances in biomedical technology are incorporated ethically into research and medicine.
Exciting advances in medicine and health are being researched in precision medicine projects recently funded by the George and Judy Marcus Program in Precision Medicine Innovation.
New research by UCSF scientists could accelerate – by 10 to 100-fold – the pace of many efforts to profile gene activity, ranging from basic research into how to build new tissues from stem cells to clinical efforts to detect cancer or auto-immune diseases by profiling single cells in a tiny drop of blood.
With one drug to shut down its progression and another to undo its damage, plus a worldwide effort stalking the origins of multiple sclerosis, MS doesn’t stand a chance.
The new UCSF Center for BRCA Research – which spans basic and translational research, clinical care and education – provides a one-stop resource for patients and individuals who carry BRCA1 and BRCA2 mutations.
UCSF researchers have discovered that the chances of survival for patients with pancreatic adenocarcinoma (PDAC) — the most common type of pancreatic cancer — may depend in part on how tense their tumors are.
In a study of 10 children published online in the American Journal of Human Genetics on April 14, the researchers linked a constellation of birth defects affecting the brain, eye, ear, heart and kidney to mutations in a single gene, called RERE.
An international team of scientists have for the first time identified genes and gene regulatory elements that are essential in wing development in the Natal long-fingered bat (Miniopterus natalensis), a species widely distributed in eastern and southern Africa.
UCSF researchers are using big data to find cancer treatments by mapping gene networks and screening existing cancer drugs to test their effectiveness against dozens of different cancer gene variants.
UCSF School of Pharmacy faculty member Adam Abate has been named a recipient of the Presidential Early Career Award for Scientists and Engineers.
A newly discovered human gene mutation appears to contribute both to unusual sleep patterns and to heightened rates of seasonal depression, according to new research from UCSF.
Researchers at UCSF and Johns Hopkins may have found a new way to diagnose Lyme disease, based on a distinctive gene “signature” they discovered in white blood cells of patients infected with the tick-borne bacteria.
With a tiny sequencing machine that plugs into a laptop’s USB port, UCSF’s Charles Chiu aims to diagnose infectious diseases quickly – and even catch the next wave before it strikes.
An international team of scientists has discovered that estrogens reverse a striking behavioral abnormality in zebrafish carrying mutations in a gene known to cause autism in humans.
A study of 35 families led by a UCSF psychiatric researcher showed for the first time that the structure of the brain circuitry known as the corticolimbic system is more likely to be passed down from mothers to daughters than from mothers to sons or from fathers to children of either gender.