Zebrafish-to-Patient Approach Speeds Search for Childhood Epilepsy Treatments
In an unprecedented leap from lab to patients, a potential treatment for childhood epilepsy identified in experiments with zebrafish.
University of California San Francisco
Give to UCSFIn an unprecedented leap from lab to patients, a potential treatment for childhood epilepsy identified in experiments with zebrafish.
New research is paving the way to a precision medicine approach to the diagnosis and treatment of patients with traumatic brain injury.
A molecular key to aging of the blood and immune system has been discovered in new research conducted at UCSF.
A type of herpes virus that infects about half of the U.S. population has been associated with risk factors for type 2 diabetes and heart disease in normal-weight women aged 20 to 49.
Research uses brain “organoids” — tiny 3D models of human organs that scientists grow in a dish to study disease — to identify root causes of MDS, a rare genetic disorder that causes fatal brain malformations.
Fifteen UCSF faculty members have been named to the first cohort of Chan Zuckerberg Biohub Investigators.
Poor performance on a simple odor identification test was associated with a significantly increased risk of developing dementia years later.
Lily Jan and Yuh-Nung Jan have received the 2017 Vilcek Prize in Biomedical Science, which recognizes extraordinary contributions to biomedical research made by immigrants to America.
Distinct sets of genetic defects in a single neuronal protein can lead either to infantile epilepsy or to autism spectrum disorders.
A common treatment for irregular heartbeats known as catheter ablation may result in the formation of brain lesions when it is performed on the left side of the heart.
For concussion sufferers, physicians may now be able to predict early on who is more likely to continue experiencing symptoms months or years after the head-jarring event.
Children with severe cases of epilepsy such as Dravet syndrome are finding new and unexpected cures thanks to determined pediatricians and translational research at UCSF.
UC San Francisco and Pfizer Inc.’s Centers for Therapeutic Innovation have renewed an agreement to identify and develop biologic compounds against both known and novel targets.
Researchers at UCSF have developed a new optogenetic tool that can be used to completely eliminate single cells from brain networks in animals. The researchers believe the new tool will enable exquisitely precise experiments to help researchers understand how each cell contributes to the whole.
The UCSF community is deeply saddened to learn of the passing of William K. Bowes Jr., a Bay Area venture capitalist whose dedicated volunteer service and generous philanthropy supported medical research, access to college, higher education and the arts.
Margot Kushel’s research, clinical and personal work with homeless patients stretches back to the 1990s when she was a medical resident at ZSFG.
In findings that show the effectiveness of a new strategy for treating multiple sclerosis, researchers are reporting positive results from three large, international, multicenter Phase III clinical trials of the investigational drug ocrelizumab in both relapsing multiple sclerosis and primary progressive multiple sclerosis.
UCSF scientists have discovered an unexpected mechanism the brain uses to seamlessly compensate when speech sounds are obscured by noise.
Stories about sensory processing disorder, videos about “zombie” cancer cells, and news about the effects of caffeine and alcohol on the heart were among the topics that most engaged our readers in 2016.
Beta blockers are effective in reducing the risk of death in older nursing home residents after a heart attack, but may impair their ability to perform daily functions independently.
UC San Francisco and the Veterans Affairs Medical Center in San Francisco has found that change in telomere length over time is important.
A shared biological mechanism may drive the progression of both Alzheimer’s disease and chronic traumatic encephalopathy, a neurodegenerative condition associated with repeated concussions and brain trauma.
UCSF is hosting the 2017 Breakthrough Prize Symposium on Dec. 5, an event that will feature 14 TED Talk-style presentations about the latest advances in life sciences, physics and mathematics.
UCSF researchers identified fetal brain tissue cells that are targeted by the Zika virus and determined that azithromycin can prevent the virus from infecting these cells.
UCSF researchers have received $1.2 million for their work to make imaging machines smarter, so they can detect neurological emergencies and triage patients for immediate treatment.
UCSF researchers found a way to pause the development of early mouse embryos for up to a month in the lab, a finding with implications for assisted reproduction, regenerative medicine, aging and cancer.
Next-generation sequencing for patients at UCSF Medical Center is prompting changes in brain tumor diagnoses for some children and a retooling of treatment plans in many cases.
UCSF's David Julius is the recipient of the 2017 Human Frontier Science Program Nakasone Award, which honors scientists who have made key breakthroughs in fields at the forefront of the life sciences.
More than one in four older adults have not engaged in planning for end-of-life care or directives, despite significant public efforts to encourage the practice.
The UCSF Weill Institute for Neurosciences has named the first recipients of the UCSF Weill Innovation and Scholar Awards as part of the institute’s goal to support high-risk, high-reward research.