Researchers Create Cellular “ORACLs” to Aid Drug Discovery
A team of researchers at UCSF has devised a new approach for early stage drug discovery that uses techniques from the world of computer vision in combination with a powerful new tool.
University of California San Francisco
Give to UCSFA team of researchers at UCSF has devised a new approach for early stage drug discovery that uses techniques from the world of computer vision in combination with a powerful new tool.
These are the stories that engaged our visitors in 2015 – whether it was reading in-depth about brain rejuvenation, watching mesmerizing cells in motion on social media, or learning about the latest discoveries that could soon lead to new treatments.
We asked experts across UCSF to identify what's ahead in how we approach research, what disease areas will see major advances, and where basic science will be translating into real treatments.
A new study by UCSF scientists shows that the proportion of normal cells, especially immune cells, intermixed with cancerous cells in a given tissue sample may significantly skew the results of genetic analyses and other tests performed both by researchers and by physicians selecting precision therapies.
A small study of new mothers suggests that not having graduated from high school may impact the likelihood of babies being born with shortened telomeres.
If depression is caused by flawed brain circuitry, it may be possible to shift that circuitry toward healthy neural processing instead. UCSF researchers hope to map and correct aberrant neural behavior to cure mood disorders.
As health care shifts away from a fee-for-service model as a result of the ACA, health care workers in California will be called upon to develop new skills and fill new roles, according to a study led by UCSF researchers.
HIV can lurk for a lifetime in the body, so to truly cure patients, scientists are trying to find ways to target these HIV reservoirs in a strategy known as “shock and kill.”
In a bid to end the worst epidemic in modern times, the Foundation for AIDS Research (amfAR) is funding an ambitious effort based in San Francisco to eliminate the human immunodeficiency virus (HIV) from those who are infected.
The Malaria Elimination Group, an independent international advisory group on malaria elimination convened by the Global Health Group at the University of California, San Francisco (UCSF), gathered in the Ezulwini Valley for its tenth meeting to celebrate Swaziland’s achievements. The meeting was opened on November 16, 2015 by Swaziland’s Minister of Health, Honorable Sibongile Ndlela-Simelane.
In the first U.S. safety trial of a new form of immunotherapy for type 1 diabetes, patients experienced no serious adverse reactions after receiving infusions of as many as 2.6 billion cells that had been specially selected to protect the body’s ability to produce insulin.
A new study led by UCSF researchers has found that mice who spend too much time in their thermal “comfort zone” while gorging on fatty foods more than double their risk of developing cardiovascular disease compared to mice who stayed cool while eating the same diet.
It is worthwhile to give patients expensive new drugs that can cure their hepatitis C much earlier than some insurers are now willing to pay for them, according to a UCSF study.
UCSF researchers has discovered that single-celled yeast have sensory biases that can be hacked by a carefully engineered illusion, a finding that could be used to develop new approaches to fighting diseases such as cancer.
One in 20 survivors of gunshot violence in an urban area with high crime died within five years, mainly by homicide, according to the results of a study that tracked patients after hospital discharge.
A study that tracked tens of thousands of midlife and older men for more than 20 years has found that vigorous exercise and other healthy lifestyle habits may cut their chances of developing a lethal type of prostate cancer by up to 68 percent.
UCSF researchers have found a human gene that could one day allow physicians to correct congenital deformities, regrow damaged fingers, or even mend a broken heart.
A wave of specialized immune cells entering the skin in early life may induce tolerance to the hundreds of species of so-called friendly bacteria that live on the surface of the body.
A $10 million gift from The Parker Foundation, founded by Silicon Valley entrepreneur and philanthropist Sean Parker, will establish a new research laboratory within the UCSF Diabetes Center devoted to understanding autoimmunity.
The trajectory of Bruce Miller’s work is emblematic of the integration seen within the entire neurosciences field over the last decade, as its broad range of disciplines attract unprecedented levels of investment.
The Atlantic Philanthropies is awarding UCSF and Trinity College Dublin, the University of Dublin, $177 million to create the Global Brain Health Institute, a groundbreaking venture to stem the precipitous rise in dementia by training and connecting a new generation of leaders worldwide.
An international team of scientists led by UCSF researchers has mapped out the genetic trajectories taken by melanoma as it evolves from early skin lesions, known as precursors, to malignant skin cancer.
Although adults with serious psychiatric disorders are at high risk for diabetes, a large study led by UCSF reveals that low-income patients on Medicaid are rarely screened for it.
Scientists at the UNC School of Medicine (UNC) and UCSF have created a general tool to probe the activity of orphan receptors, illuminating their roles in behavior and making them accessible for drug discovery.
In a new look at the groundbreaking iPrEx trial for people at high risk of HIV infection, UCSF researchers have identified strong evidence of efficacy for transgender women when PrEP is used consistently.
A chemical that could potentially be used in eye drops to reverse cataracts has been identified by a team of scientists from UCSF, the University of Michigan (U-M), and Washington University in St. Louis (WUSTL).
A gift of $20 million from the Ray and Dagmar Dolby Family Fund to the Department of Psychiatry at UCSF will support research on mood disorders.
Development of a surgically implantable, artificial kidney has received a $6 million boost, thanks to a new grant from the National Institute of Biomedical Imaging and Bioengineering (NIBIB).
To determine whether healthy food could help low-income people better control their diabetes, a pilot study by UCSF and Feeding America tracked nearly 700 people at food banks in California, Texas and Ohio over two years.