University of California San Francisco
Give to UCSFA large, international clinical trial led by doctors at UCSF indicates that a vaccine to prevent anal cancer is safe and effective, according to a study reported in the October 27, 2011 issue of New England Journal of Medicine.
During a decade of receiving mammograms, more than half of cancer-free women will be among those summoned back for more testing because of false-positive results, and about one in 12 will be referred for a biopsy.
<p>African American women have lower breast cancer survival rates than white women and University of California, San Francisco (UCSF) scientists are studying why – as well as how to increase their life spans.</p>
<p>Experts at UCSF and Caltech are pushing the boundaries of creative problem solving to address important clinical problems with the hope that the talent pool at both institutions, combined with an entrepreneurial spirit, will advance health care innovation.</p>
Targeting a protein that leukemia cells use to stay alive may be the key to fighting drug-resistant leukemia, a discovery that may make cancer drugs more powerful and help doctors formulate drug cocktails to cure more children of leukemia, a team led by UCSF researchers reports.
<p>Yervoy, a new cancer drug that has been approved for the treatment of late-stage melanoma – and that is being used to treat other cancers in ongoing clinical trials – is based on a strategy for boosting the immune response developed and tested by scientists from UCSF and UC Berkeley.</p>
Brain cancers are deadly more often than not, but UCSF researchers have determined that a particular genetic signature in is associated with longer survival, a discovery that may lead to better therapies for some of the deadliest brain cancers.
For patients with glioma, the most common primary brain tumor, new findings may explain why current therapies fail to eradicate the cancer. A UCSF-led team of scientists has identified for the first time that progenitor rather than neural stem cells underly a type of glioma called oligodendroglioma.
New technologies and techniques continue to accelerate the pace of discovery in human genetics research, a fact made clear by scientists who spoke about their searches for important mutations, gene variants and answers to basic biological questions at the UCSF Institute for Human Genetics’ fifth-anniversary symposium on Oct. 28.
The National Institutes of Health (NIH) on September 30 announced 52 highly competitive awards for high-risk, high-payoff research for young biomedical scientists, and UCSF tops California institutions with four recipients.
Genentech scientist Napoleone Ferrara, who has just been named the winner of a Lasker Award, is being recognized for his noteworthy achievements made when he was a postdoc at UCSF.
A UCSF-led team has discovered at least one key reason why blood stem cells are susceptible to developing the genetic mutations that can lead to adult leukemia.
A UCSF-led team has discovered a direct link between an inherited genetic mutation, a set of developmental abnormalities and a rare form of childhood leukemia called juvenile myelomonocytic leukemia, or JMML.
It is well-known that vitamin D is essential for strong and healthy bones. However, in an article in the online “In Press” section of “Trends in Endocrinology and Metabolism,” a San Francisco VA Medical Center physician reviews recent scientific literature suggesting that the vitamin may also play a role in preventing cancer, fighting infection, and controlling or preventing auto-immune disease.
Taking an innovative path toward personalized medicine, scientists for the first time will be able to eliminate – at an early point in a clinical trial — experimental drugs that show poor efficacy, dramatically shortening the time it takes to get the right medication to the right patient with breast cancer.
UCSF scientists have discovered how a mutated gene known as Kras is able to hijack mouse cells damaged by acute pancreatitis, putting them on the path to becoming pancreatic cancer cells.
A panel of experts appointed by Mayor Gavin Newsom recently presented an action plan as the approaching “age wave may bring a potential crisis in Alzheimer’s and dementia care” to San Francisco.
A UCSF analysis of published studies on the relationship between Alzheimer’s disease and smoking indicates that smoking cigarettes is a significant risk factor for the disease.
UCSF researchers have discovered inherited DNA that increases risk for the most deadly brain cancers.
A nationwide study of over 280,000 women showed that postmenopausal women who are overweight or obese have advanced breast cancer at significantly higher rates than women of normal weight or less than normal weight.