Teeth Earn Starring Role in Field of Regenerative Medicine
Ophir Klein wants to use stem cells to grow teeth. Because teeth are simple in comparison to large, vital organs, they may serve as a proving ground for regenerative medicine.
University of California San Francisco
Give to UCSFOphir Klein wants to use stem cells to grow teeth. Because teeth are simple in comparison to large, vital organs, they may serve as a proving ground for regenerative medicine.
UCSF Nobel laureate Stanley Prusiner, MD, and colleagues have called for Congress to more than quadruple annual federal funding for Alzheimer’s research, saying that with a dedicated effort, there is a chance for a breakthrough against the disease by 2020.
<p>Scientists this week are moving into the headquarters for the Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research at UCSF, where they will continue to advance a field transformed by the revolutionary achievement of Shinya Yamanaka.</p>
UCSF scientists have received two grants from the California Institute for Regenerative Medicine to refine their human embryonic stem cell-based strategies for treating neurological diseases and liver failure.
UCSF Nobel laureate Stanley B. Prusiner, professor of neurology and director of the Institute for Neurodegenerative Diseases, today (Oct. 15, 2010) was named to receive the National Medal of Science, the nation’s highest honor for science and technology.
Synuclein is a protein that can cause Parkinson’s disease, although it is not clear how. UCSF researcher Robert Edwards, MD, now has discovered that synuclein can affect signal transmission between nerve cells long before disease symptoms arise.
The National Institutes of Health (NIH) on September 30 announced 52 highly competitive awards for high-risk, high-payoff research for young biomedical scientists, and UCSF tops California institutions with four recipients.
The UCSF Diabetes Center symposium marks its 10th anniversary.
UCSF environmental health specialist Gina Solomon is calling for improved scientific study of and publicly available and robust data about the health hazards posed by the BP oil disaster.
A UCSF-led team has discovered at least one key reason why blood stem cells are susceptible to developing the genetic mutations that can lead to adult leukemia.
In neurodegenerative diseases, clumps of insoluble proteins appear in patients’ brains. These aggregates contain proteins that are unique to each disease, such as amyloid beta in Alzheimer’s disease, but they are intertwined with small amounts of many other insoluble proteins that are normally present in a soluble form in healthy young individuals.
Stefan Habelitz, an engineer and materials scientist, is blazing a new research trail by investigating tooth enamel in the UCSF School of Dentistry's Marshall Lab, where researchers fruitfully focus on every facet of teeth, knowing they’re nothing to take for granted…
A UCSF-led team has discovered a direct link between an inherited genetic mutation, a set of developmental abnormalities and a rare form of childhood leukemia called juvenile myelomonocytic leukemia, or JMML.
UCSF has hired two senior managers to strengthen the University’s research enterprise.
Larissa Podust, PhD, is working on a new drug for Chagas disease, a neglected scourge.
A novel technique created at UCSF to deliver a growth factor directly to brain cells has shown promising results in treating Parkinson's symptoms and could enter human clinical trials as early as next year.
A commercial brain fitness program has been shown to improve memory in older adults, at least in the period soon after training. The findings are the first to show that practicing simple visual tasks can improve the accuracy of short-term, or “working” visual memory.
A recent book by UCSF sociologist Patrick Fox, PhD, helps us understand a patient’s perspective in Alzheimer’s disease.
A new study by UCSF cardiologists and researchers found that high concentrations of cocoa flavanols decrease blood pressure, improve the health of blood vessels and increase the number of circulating angiogenic cells in patients with heart disease. The findings indicate that foods rich in flavanols – such as cocoa products, tea, wine, and various fruits and vegetables – have a cardio-protective benefit for heart disease patients.
The Veterans Health Research Institute or NCIRE will present “The Brain at War: Neurocognitive Consequences of Combat” today (June 17).
For his groundbreaking work on the sensation of touch, David Julius, PhD, professor and chair of the UCSF Department of Physiology, has been named to receive the 2010 Shaw Prize in Life Sciences and Medicine.
UCSF scientists have discovered a new stem cell in the developing human brain. The cell produces nerve cells that help form the neocortex - the site of higher cognitive function -- and likely accounts for the dramatic expansion of the region in the lineages that lead to man, the researchers say.
UCSF researchers have created the first transgenic mouse to display the earliest signs of Parkinson’s disease using the genetic mutation that is known to accompany human forms of the disease.
A UCSF-led study examining the impact of statins on the progression of multiple sclerosis found a lower incidence of new brain lesions in patients taking the cholesterol-lowering drug in the early stages of the disease as compared to a placebo.
A new report by the Institute of Medicine has found that military service in the Persian Gulf War is a cause of post-traumatic stress disorder in some veterans.
UCSF scientists report that they were able to prompt a new period of “plasticity,” or capacity for change, in the neural circuitry of the visual cortex of juvenile mice.
UCSF scientists have used a novel cell-based strategy to treat motor symptoms in rats with a disease designed to mimic Parkinson’s disease. The strategy suggests a promising approach, the scientists say, for treating symptoms of Parkinson’s disease and other neurodegenerative diseases and disorders, including epilepsy.
People are paying close attention to pediatric endocrinologist Robert Lustig’s message that the obesity epidemic can be blamed on a marked increase in the consumption of a type of sugar called fructose.
A panel of experts appointed by Mayor Gavin Newsom recently presented an action plan as the approaching “age wave may bring a potential crisis in Alzheimer’s and dementia care” to San Francisco.