Personalizing Prostate Cancer Screening May Improve Accuracy of Detection
Taking into account genetic factors that can change PSA levels not associated with cancer, the screening accuracy can be improved.
University of California San Francisco
Give to UCSFTaking into account genetic factors that can change PSA levels not associated with cancer, the screening accuracy can be improved.
In a first, researchers have identified chronic pain pathways in individuals directly from their neural activity, showing promising paths forward for treatment.
UCSF is the first hospital in California to offer pharmacogenetic testing for smarter prescribing. Testing identifies genetic makeup and tailors medications to improve efficacy and avoid lethal drug reactions.
From birth, Samantha has had four surgeries for heart disease. Her last surgery was aided by a 3D-printed replica of her heart, providing a detailed understanding of her heart’s anatomy. The surgery’s success allowed the now 15-year-old to lead a more normal life.
What is “social prescribing” and what is UCSF doing to promote it? UCSF experts address the health ramifications of social isolation.
The WISDOM 2.0 study aims to transform breast cancer screening by using a personalized approach and will expand to women as young as 30.
Vissers’ work on RNA tags helped found the field of epitranscriptomics, the study of how chemical marks on RNA, rather than their sequence alone, dictate the function of the molecules.
Three UCSF researchers were named 2022 fellows by the American Association for the Advancement of Science (AAAS), one of the highest honors in science.
In a breakthrough, HT became the first person in the world to receive gene-corrected stem cells for Artemis-SCID. His new immune system is life-changing.
Through decades of biobanking at UCSF, researchers were able to comprehensively map intra-cellular signaling in the cells of recurrent glioblastoma, identifying novel cell-extrinsic therapeutic targets.
Promises from companies leap ahead of medical science in promoting the use of smartwatches to screen for heart rhythm disorders says UCSF’s Gregory Marcus.
Using a protocol developed at UCSF, physicians have successfully treated a fetus with a devastating genetic disorder for the first time, and the child is now thriving as a toddler.
Bacteria in our guts may play a significant role in the metabolism of anti-cancer drugs that are critical for treating colon cancer and other types of cancers.
A new diagnostic method that applies machine learning to advanced genomics data from both microbe and host to identify and predict sepsis cases was developed by researchers at UCSF, the Chan Zuckerberg Initiative, and CZ Biohub.
Cystic fibrosis is missed more often in newborn screenings for non-white than white babies, creating higher risk for irreversible lung damage and other serious outcomes in Black, Hispanic, Asian, American Indian and Alaska Native newborns.
Scientists at UCSF have developed a new way of looking at sex-biased diseases that is rooted in evolutionary biology.
UCSF has revealed how blood vessel cells develop in the prenatal human brain, paving the way to fully understand the role of these cells in healthy brain development and disease.
A new therapy pulls forward a mutated version of the KRAS protein to help the immune system recognize and destroy cancer cells.
A new variation of the CRISPR-Cas9 gene editing system makes it easier to re-engineer massive quantities of cells for therapeutic applications. The approach, developed at Gladstone Institutes and UC San Francisco (UCSF), lets scientists introduce especially long DNA sequences to precise locations in the genomes of cells at remarkably high efficiencies without the viral delivery systems that have traditionally been used to carry DNA into cells.
T cells used in immunotherapy treatments can get exhausted and shut down by fighting cancer cells and tumors. Using a CRISPR-based edit on these cells’ genomes, researchers at UCSF and Gladstone Institutes have rendered the therapeutic cells more resilient against tumors.
A new national study led by UCSF found that more sophisticated devices that pair with smartphones don’t lead to better blood pressure control than home-use blood pressure cuffs.
Blood tests taken within 24 hours of a traumatic brain injury (TBI) flag which patients are likely to die and which patients are likely to survive with severe disability, according to a study headed by UCSF, the University of Pennsylvania and the University of Michigan.
A new "subway map" of immune networks connects gene variation to risk for autoimmune disease.
When Cheryl Broyles was diagnosed with glioblastoma, her goal was to outlive the disease’s 15-month prognosis. That was 22 years ago. Broyles’ survival has been the result of luck, tumor location, and cutting-edge treatment and diagnostics.
The latest advances in cancer care and research will be showcased at the annual American Society of Clinical Oncology (ASCO) Annual Meeting, the world’s largest clinical cancer meeting.