Zika in Fetal Brain Tissue Responds to a Popular Antibiotic
UCSF researchers identified fetal brain tissue cells that are targeted by the Zika virus and determined that azithromycin can prevent the virus from infecting these cells.
University of California San Francisco
Give to UCSFUCSF researchers identified fetal brain tissue cells that are targeted by the Zika virus and determined that azithromycin can prevent the virus from infecting these cells.
UCSF researchers are learning more about what guides the formation of crystals that malaria parasites leave behind so they can work toward new treatments.
Graduate student Lauren Rodda captured a microscopic mage of a mouse gut, which highlights her work to understand the germinal center, where immune cells compete to be the best at recognizing an invading pathogen.
Researchers at UCSF and the academically affiliated Gladstone Institutes have used a newly developed gene-editing system to find gene mutations that make human immune cells resistant to HIV infection.
UCSF has ranked as one of the top 20 universities in the world, according to the 2017 Best Global Universities rankings released Tuesday by U.S. News & World Report.
Lenore Pereira, a virologist and professor in School of Dentistry’s Department of Cell and Tissue Biology, is in the middle of crucial research to understand how the mosquito-borne Zika virus harms the babies of women infected during pregnancy.
Using a mouse model of multiple sclerosis, UCSF scientists demonstrated that regenerating myelin can both protect neurons from damage and restore lost function.
UCSF scientists have engineered human immune cells that can precisely locate diseased cells anywhere in the body and execute a wide range of customizable responses, including the delivery of drugs or other therapeutic payloads directly to tumors or other unhealthy tissues.
Joe DeRisi, co-director of the new Chan Zuckerberg Biohub at Mission Bay, speaks about his vision for the Biohub and what researchers can look forward to.
UCSF, Stanford and UC Berkeley will join forces in a new biomedical science research center funded by a $600 million commitment from Facebook CEO and founder Mark Zuckerberg and pediatrician Priscilla Chan.
Gut microbes present in some one-month-old infants predict a three-fold higher risk of developing allergic reactions by age two and asthma by age four.
The abundance of a subtype of white blood cells in melanoma tumors can predict whether or not patients will respond to a form of cancer immunotherapy known as checkpoint blockade, according to a new study led by UCSF researchers and physicians.
A new study led by UCSF scientists shows that a bacterium commonly found in the human gut is overrepresented in patients with a rare, often disabling autoimmune disease known as neuromyelitis optica.
Zika virus can infect numerous cell types in the human placenta and amniotic sac, according to researchers at UCSF and UC Berkeley who show in a new paper how the virus travels from a pregnant woman to her fetus.
Using advanced imaging technology that allowed them to spy on interactions among cells in the lymph nodes of living mice, a research team led by UCSF scientists has identified a cell that is a key player in mounting the immune system’s defense against cancer.
Symptoms of infection with the Zika virus in Brazil may be masked by simultaneous infection with other mosquito-spread viruses common in the same region — such as dengue fever and chikungunya viruses — pointing to the need for comprehensive testing, according to a study led by a UCSF expert in DNA-based diagnostics in collaboration with Brazilian researchers.
A previously unidentifiable type of low-grade inflammation may explain why common anti-inflammatory drugs such as aspirin have shown promise against some types of cancer – even when patients don’t display typical signs of inflammation.
A research team led by UC San Francisco scientists has discovered a cellular signaling system that regulates the virulence of Cryptococcus neoformans, a fungus that has been estimated to cause nearly a million cases of meningitis worldwide per year, about 625,000 of which are fatal.
UC San Francisco researchers have shed light on how the immune system of a fetus can run amok, triggering inflammation in the developing intestines that protrude outside of the body through a hole beside the belly button.
With one drug to shut down its progression and another to undo its damage, plus a worldwide effort stalking the origins of multiple sclerosis, MS doesn’t stand a chance.
Global malaria eradication is possible within a generation, but only with renewed focus, new tools and sufficient financial support, according to a paper published in The Lancet by the Global Health Group’s Malaria Elimination Initiative at UCSF.
Renowned UCSF immunologist Jeffrey Bluestone, PhD, has been named president and CEO of the Parker Institute for Cancer Immunotherapy, a national initiative launched with a $250 million grant from The Parker Foundation, established by Silicon Valley entrepreneur Sean Parker.
Strengthening the link between Zika virus and microcephaly, scientists at UCSF have discovered that a protein the virus uses to infect skin cells and cause a rash is present also in stem cells of the developing human brain and retina.
Scientists at UC San Francisco have been able to directly observe, for the first time, how invasive cancer cells create a beachhead as they migrate to the lung in a mouse model of metastatic cancer.
UCSF hosted a Zika symposium to bring together Bay Area experts and health officials to to help focus the research agenda as scientists around the world scrambling for information the virus.
Research by UCSF scientists has opened up a surprising new avenue for potential therapies to reduce the risk of type 2 diabetes and other metabolic disorders that are associated with chronic tissue inflammation in obesity.
Pregnant women can be protected from malaria, a major cause of prematurity, low birth weight and death in infants in Africa, with dihydroartemisinin-piperaquine (DP), an artemisinin combination therapy that is already widely used to treat malaria in adults, according to a study by researchers at UC San Francisco and in Uganda.
Leading microbiome researchers recently came to UCSF to share the newest insights about how improving our relationship with our bodies’ microbial ecosystems could be the next big breakthrough in treating metabolic disease.
Researchers at UCSF and Johns Hopkins may have found a new way to diagnose Lyme disease, based on a distinctive gene “signature” they discovered in white blood cells of patients infected with the tick-borne bacteria.
With a tiny sequencing machine that plugs into a laptop’s USB port, UCSF’s Charles Chiu aims to diagnose infectious diseases quickly – and even catch the next wave before it strikes.