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Parkinson's Disease Protein Impedes Nerve Signaling Long Before Brain Cells Die
Synuclein is a protein that can cause Parkinson’s disease, although it is not clear how. UCSF researcher Robert Edwards, MD, now has discovered that synuclein can affect signal transmission between nerve cells long before disease symptoms arise.
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UCSF Tops California Universities with Four NIH Director's New Innovator Awards
The National Institutes of Health (NIH) on September 30 announced 52 highly competitive awards for high-risk, high-payoff research for young biomedical scientists, and UCSF tops California institutions with four recipients.
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Diabetes Center Celebrates 10 Years of Success, Charts Future Course
The UCSF Diabetes Center symposium marks its 10th anniversary.
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Ferrera's Lasker Award-Winning Research Began at UCSF
Genentech scientist Napoleone Ferrara, who has just been named the winner of a Lasker Award, is being recognized for his noteworthy achievements made when he was a postdoc at UCSF.
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Can Post-Traumatic Stress Disorder Be Stopped Before it Begins?
UCSF researchers at the San VA Medical Center have been working with US Air Force officers to develop and field test Deployment Anxiety Reduction Training with the goal of stopping post-traumatic stress disorder before it starts.
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Environmental Health Expert Calls for Improved Scientific Study of Gulf Coast Oil Disaster
UCSF environmental health specialist Gina Solomon is calling for improved scientific study of and publicly available and robust data about the health hazards posed by the BP oil disaster.
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UCSF obesity study receives widespread media coverage
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Accolades Mount for Esteemed UCSF Human Geneticist Charles Epstein
As a leader at UCSF and in the human genetics medical research community nationally and internationally, Charles J. Epstein, MD, has helped guide human genetics into the molecular age and into the spotlight of modern medicine.
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Obesity rates decline for many adolescents but disparities worsen
Obesity rates have started to decline and level off for many adolescents, but continue to increase for certain racial and ethnic minorities, according to a new UCSF-led study.
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Blood Stem Cell, Leukemia Link Illuminated in UCSF-Led Study
A UCSF-led team has discovered at least one key reason why blood stem cells are susceptible to developing the genetic mutations that can lead to adult leukemia.
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Physicians call for more flexible end-of-life planning
Specialists in geriatric medicine at the San Francisco VA Medical Center and the VA Connecticut Healthcare System call the traditional approach of advance care planning “fundamentally flawed,” and propose a new paradigm.
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Mutant mouse reveals potential genetic pathway for alcoholism
A mutation found in a mouse gene that also appears in humans might provide new insights into the genetic roots of alcoholism, according to a study led by researchers at the Ernest Gallo Clinic and Research Center and UCSF. The study appears in the August 12, 2010, edition of “<i>PLoS Genetics</i>.”
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Proteins Linked with Alzheimer's, Other Neurodegenerative Diseases Found to Clump in Normal Aging
In neurodegenerative diseases, clumps of insoluble proteins appear in patients’ brains. These aggregates contain proteins that are unique to each disease, such as amyloid beta in Alzheimer’s disease, but they are intertwined with small amounts of many other insoluble proteins that are normally present in a soluble form in healthy young individuals.
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UCSF-led team discovers familial link in rare childhood leukemia
A UCSF-led team has discovered a direct link between an inherited genetic mutation, a set of developmental abnormalities and a rare form of childhood leukemia called juvenile myelomonocytic leukemia, or JMML.
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Tooth Enamel: Nature’s Crowning Achievement
Stefan Habelitz, an engineer and materials scientist, is blazing a new research trail by investigating tooth enamel in the UCSF School of Dentistry's Marshall Lab, where researchers fruitfully focus on every facet of teeth, knowing they’re nothing to take for granted…
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Are Higher Testosterone Levels Associated with Greater Heart Risk?
Testosterone in men has become a hot health topic. New studies, including one by UCSF researchers, now are sparking a controversy over the role of testosterone in heart disease.
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Cholesterol levels in young adults predict risk of future heart disease
Young people with even modestly elevated cholesterol levels are more likely to develop coronary artery calcium and atherosclerosis later in life, according to a study by UCSF researchers.
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Hildebrand-Zanki and Auger Will Lead Initiatives for UCSF Office of Research
UCSF has hired two senior managers to strengthen the University’s research enterprise.
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Anti-Parasite Drugs for Neglected Chagas Disease Are in the Works
Larissa Podust, PhD, is working on a new drug for Chagas disease, a neglected scourge.
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UCSF Gene Therapy Method Allays Parkinson's Symptoms
A novel technique created at UCSF to deliver a growth factor directly to brain cells has shown promising results in treating Parkinson's symptoms and could enter human clinical trials as early as next year.
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Brain fitness program study reveals visual memory improvement in older adults
A commercial brain fitness program has been shown to improve memory in older adults, at least in the period soon after training. The findings are the first to show that practicing simple visual tasks can improve the accuracy of short-term, or “working” visual memory.
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NEJM Editorial cites toll of disparity on chronic disease
The heavy burden of hunger in the United States helps explain why the poor are at higher risk for obesity, high blood pressure and diabetes, according to an editorial in the July 1 <i>New England Journal of Medicine</i> co-authored by two UCSF faculty members.
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Weight loss reduces hot flashes in overweight and obese women
A new study shows that overweight and obese women who suffer from hot flashes can reduce the severity of their hot flashes if they lose weight through diet or exercise.
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Reframing Alzheimer's: Book Helps Deepen Understanding of Memory Loss
A recent book by UCSF sociologist Patrick Fox, PhD, helps us understand a patient’s perspective in Alzheimer’s disease.
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Anxiety linked to increased cardiac risk in heart disease patients
Heart disease patients with anxiety disorder were significantly more likely to experience stroke, heart failure, heart attack, transient ischemic attack (mini-stroke), or death than heart disease patients without anxiety, in a study led by researchers at the San Francisco VA Medical Center.
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Cocoa flavanols improve vascular and blood pressure measures for coronary artery disease patients
A new study by UCSF cardiologists and researchers found that high concentrations of cocoa flavanols decrease blood pressure, improve the health of blood vessels and increase the number of circulating angiogenic cells in patients with heart disease. The findings indicate that foods rich in flavanols – such as cocoa products, tea, wine, and various fruits and vegetables – have a cardio-protective benefit for heart disease patients.
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Veterans Health Research Institute Presents Brain at War Conference Today
The Veterans Health Research Institute or NCIRE will present “The Brain at War: Neurocognitive Consequences of Combat” today (June 17).
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McKerrow's Parasitic Disease Research Garners Mendel Medal
James McKerrow, leader of the Sandler Center for Drug Discovery at UCSF, was honored with the 2009 Mendel Medal for his work identifying the vulnerabilities of disease-causing parasites and for devising new strategies to fight them.
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Vitamin D: Not just for bones, says San Francisco VA physician
It is well-known that vitamin D is essential for strong and healthy bones. However, in an article in the online “In Press” section of “Trends in Endocrinology and Metabolism,” a San Francisco VA Medical Center physician reviews recent scientific literature suggesting that the vitamin may also play a role in preventing cancer, fighting infection, and controlling or preventing auto-immune disease.