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UCSF scientists engineered old fibroblast cells to turn their genes on and off in the same way as young fibroblasts. The old fibroblasts were rejuvenated: they multiplied (green) and produced more of the material used to make the "skeletons," or extracellular matrix, of our organs (red). Image by Li Lab
Self-administered injectable contraceptives, which are progestin-only shots taken at home every three months, have been available for over 20 years but remain underutilized. Interest in these options increased during COVID-19. A national study has revealed that the primary barriers to their use are not related to patient capability or clinical safety.
Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment by using a patient’s own T-cells to target tumors. However, they can cause rare but potentially fatal cardiac inflammation
Hematologists and oncologists from UC San Francisco shared research results and clinical guidance at the world’s premier meeting for malignant and non-malignant hematology at the American Society of
Millions of people in the U.S. and around the world are living with hepatitis C virus (HCV). But over the past decade, direct-acting antivirals (DAA) have proven effective against HCV, curing more
Aortic stenosis is a narrowing of the aortic valve which connects the heart to the rest of the body. It affects millions of people and can be fatal if left untreated. At present, there are no
UCSF researchers showed that estrogen can turn on pain signals in the gut, offering new insights into conditions like irritable bowel syndrome, especially for women.
UCSF has acquired two life sciences buildings next to its Mission Bay campus to create urgently needed space for a new home for the UCSF School of Dentistry, a leading-edge hub for interprofessional education, expanded research capacity, and increased access to high-quality dental care for the community.
New research shows a jump in pediatric medical spending on behavioral health from 2011 to 2022, highlighting the urgent need to boost access and capacity for treatment.
A study finds personalized breast cancer screening based on risk reduces advanced cancers and ensures safe, tailored mammogram frequency.
Three UCSF Health hospitals have been named to the Leapfrog list of Top Hospitals for safety and quality.
A study shows that young people who use tanning beds have more skin mutations including cells known to lead to skin cancer.
The American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP®) has recognized UCSF Health for achieving meritorious outcomes for surgical patient care in 2024.
In the last few years, progress has been made in the fight against Alzheimer’s disease with a class of therapies called anti-amyloid antibodies (anti-Aβ). These monoclonal anti-Aβs are proteins made
UCSF Benioff Children's Hospitals is expanding access to lifesaving care through a new, dedicated neonatal transport team based in Oakland. The new unit, in addition to the existing San Francisco unit, allows the hospitals to better serve patients coming in from referring hospitals from around the region.
UCSF Health-UCSF Medical Center has again received the highest possible national rating of “high performing” for maternity care by U.S. News & World Report.
Matthew Growdon's study finds "prescription cascades" where drug side effects lead to unnecessary second prescriptions, causing further harm and costly hospitalizations.
UCSF researchers have made strides toward an HIV cure, showing experimental immunotherapy can help control the virus without long-term antiretroviral therapy (ART). In a small study, 7 of 10 participants maintained low HIV levels after stopping medications, reprogramming their immune systems.
Scientists have thought that when we hear language, the brain processes it the same way, whether it's familiar or foreign. A new study reveals that exposure to a language changes how certain clusters of neurons respond to the familiar sounds. From those changes, we develop the understanding of syllables, words, and syntax.
A UCSF-led study reveals combining genetic risk factors like APOE4 with cardiovascular risks such as high LDL, obesity, and hypertension can predict dementia likelihood. Lifestyle changes targeting modifiable risks may delay or prevent symptoms, offering hope for proactive dementia prevention strategies.
Using a mix of outreach methods – texts, automated calls, and live phone calls – can improve follow-up care for discharged patients, especially hard-to-reach groups. UCSF Health’s study found this approach significantly boosts engagement and reduces disparities in care, particularly among African American patients.
Differentiated thyroid cancer is the most frequently diagnosed thyroid cancer in the U.S. Recently, the American Thyroid Association (ATA) released new practice guidelines for Differentiated thyroid
Late-breaking results from clinical trials, debates about lifestyle choices and cardiovascular risk, and improving clinical care with generative AI are among the topics being presented by UC San
Senescent fibroblasts are aging cells in connective tissue that no longer divide and protect against tumor development. Yet, these same cells can promote cancer growth in a laboratory setting.Until
A study found that drinking at least a cup of caffeinated coffee daily significantly lowered the risk of atrial fibrillation, a common heart condition.
Development of a novel RNA biomarker for prostate cancer detection using seminal fluid and mismatched opioid prescriptions following urologic surgery are among the topics being presented by UCSF
New testing in maternal hyperoxia — giving extra oxygen to pregnant people — shows that prenatal interventions might yield better outcomes for babies with congenital heart disease.
To address the specific challenges faced by older adults with inflammatory bowel disease (IBD), UCSF Health created the UCSF IBD Longevity Clinic to provide comprehensive and specialized care for patients aged 65 and older with this chronic condition.
Doctors have reduced opioid prescribing since the opioid epidemic’s peak, but a UCSF study found that this trend affects nursing home residents with chronic pain. An analysis of 3M residents saw declines in opioid use, with racial disparities in prescribing.
In a first, experts have created treatment guidelines and recommendations for women who experience low sexual desire or Hypoactive Sexual Desire Disorder (HSDD), a common yet largely undertreated issue experienced by women.