Here’s How to Prime Tumors to be Defeated by Cancer Immunotherapy
Scientists discover how to rouse the immune system around "cold" tumors, making them vulnerable to cancer-killing immune therapies with checkpoint inhibitors.

University of California San Francisco
Give to UCSFScientists discover how to rouse the immune system around "cold" tumors, making them vulnerable to cancer-killing immune therapies with checkpoint inhibitors.
CT scans may account for 5% of all cancers annually, according to a new study that cautions against overusing and overdosing CTs.
Cardiology experts from UCSF Health presented new research and clinical findings at the American College of Cardiology’s (ACC) 74th Annual Scientific Session and Expo in Chicago, March 29-31.
A new study found that female hormones can suppress pain signals before they reach the brain by making immune cells near the spinal cord produce opioids.
Neuro-immunologist Stephen Hauser, MD, whose maverick thinking transformed the treatment landscape for patients with multiple sclerosis (MS), has received the 2025 Breakthrough Prize in Life Sciences.
UCSF Health’s Lung Transplant program has been awarded INTERLINK’s 2025 Chairman’s Award for Transplant Excellence as the top-performing lung transplant program in the nation. The UCSF program, which
A new method of alerting clinical care providers holds promise for increasing treatment and improving survival for patients with severe aortic stenosis, a valvular heart condition that can be deadly when left untreated.
Alzheimer’s disease is characterized by a host of recognizable cognitive symptoms, but many non-cognitive symptoms like changes in sleep, anxiety and depression can be early signs of the disease.
A study followed the sleep patterns of older female participants to see if specific patterns of change were associated with a higher risk of dementia. The participants, whose average age was 83, were monitored by wrist devices that track movement and time spent asleep.
A cancer drug developed ten years ago at UCSF can also put the brakes on one of prostate cancer's deadliest molecular tricks.
Thousands of people at UCSF work with the purpose of offering hope for the future of every child. Gabby, HT and Brooklyn are among the thousands whose lives have been changed by the research that springs from UCSF’s mission.
Locating seizure onset zones is a critical requirement for epilepsy surgery. This often relies upon intracranial recordings, but finding the exact zone can still present challenges. An experimental study capturing seizures on grid electrode arrays of varying density found that higher density grid arrays produced more specificity in seizure onset areas.
Orthopedic surgery experts from UCSF Health will present new clinical research findings and cutting-edge surgical techniques at the American Academy of Orthopaedic Surgeons’ (AAOS) annual meeting.
The Bronchiectasis and NTM Association has accepted UC San Francisco (UCSF) into its Bronchiectasis and NTM Care Center Network (CCN), recognizing UCSF’s dedication to providing high-quality medical
Patients who struggle to take daily HIV pills can benefit from long-acting injectable treatments, a new study by researchers at UC San Francisco has found.
A paralyzed man was able to move a robotic arm and fingers simply by imagining himself doing so, with the help of brain signals decoded through a computer.
Why do women's brains fare better in aging than men's? A study found that the second, 'silent' X chromosome turns on in the brain of old female mice and improves learning and memory – opening new paths to slow the decline in men and women.
COPA syndrome causes lung hemorrhaging starting in childhood. But one in three people with the disease mutation are spared. UCSF scientists have discovered how a separate gene variant protects those relatives – lighting the way to a possible cure.
A new UCSF study shows that the human lungs have just as many blood-producing stem cells as bone marrow. These stem cells are a precious resource for a variety of therapies for conditions like leukemia or lung diseases.
How did humans evolve brains capable of complex language, civilization, and more? Scientists at UC San Francisco recently found that parts of our chromosomes have evolved at breakneck speeds to give us an edge in brain development compared to apes.
Brian T. Feeley, MD, FAOSS, UCSF orthopaedic surgeon and researcher, has been awarded the 2025 Kappa Delta Elizabeth Winston Lanier Award by American Academy of Orthopaedic Surgeons (AAOS). He was
UCSF Health has opened the Peninsula Outpatient Center in downtown Burlingame to bring the health system’s world-class specialty and cancer care close to home with a fifth location on the Peninsula.
UCSF scientists have found that some cancers, like brain cancer, make unique, jumbled proteins that make them stand out. These newly recognized cancer-specific proteins, or antigens, could speed the development of potent immunotherapies that recognize and attack hard-to-treat tumors.
A study found that B12 requirements may be too low for some people, putting them at risk for cognitive decline.
Saras Ramanathan, MD, has been appointed as editor-in-chief of the Journal of Academic Ophthalmology (JAO). JAO is the official publication of the Association of University Professors of Ophthalmology
Stroke experts from UCSF Health presented new research and clinical findings at the annual the American Stroke Association’s International Stroke Conference (ISC25), the world’s premier meeting dedicated to the science and treatment of cerebrovascular disease and brain health. This year’s meeting was held Feb. 5–7, 2025, in Los Angeles.
UCSF scientists are taking the first steps toward creating a new type of antibiotic that uses an unusual virus to defeat antibiotic-resistant bacteria.
UCSF scientists discover how cancer cells hijack the protein factory of the cell to churn out MYC protein, the driver of 70% of all cancers.
Scientists used implanted fat cells to gobble up available nutrients around cancer tumors, starving the tumors to death.
Rates of advanced prostate cancer in California rose significantly in the decade since doctors stopped routinely screening all men. A UCSF study reinforces the need for screening that can identify potentially fatal tumors without raising false alarms about ones that pose little threat.