How to Predict Developmental Differences in Kids with Heart Defects
New testing in maternal hyperoxia — giving extra oxygen to pregnant people — shows that prenatal interventions might yield better outcomes for babies with congenital heart disease.
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This New Tech Helps Parkinson’s Patients Who Have Trouble Walking
UCSF researchers used AI to personalize Deep Brain Stimulation (DBS) for Parkinson's gait problems, leading to meaningful, customized improvements in walking and mobility—a major breakthrough for patients.
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Why Is It So Hard to Adjust When Clocks ‘Fall Back’?
Neurologist Dr. Ptacek explains how "falling back" disrupts the 24-hour circadian clock, affecting mood and performance, with mitigation tips.
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How to Turn Genes On or Off to Protect Brain Cells From Dementia
Martin Kampmann’s work, supported by the National Institutes of Science (NIH), maps cellular “decision points” that determine whether brain cells survive or die, laying the groundwork for treatments that intervene before irreversible brain damage occurs from dementia.
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How Multiple Sclerosis Harms a Brain Long Before Symptoms Appear
Image In the human brain, neurofilament light chain (NfL, shown in brown) is seen in brain cells and the neural wires that connect them. UCSF
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Scientists Used AI to Map Uncharted Areas of the Mouse Brain
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Could This Novel Therapy Calm Anxiety for Millions of Americans?
Generalized anxiety disorder affects 1 in 20 U.S. adults. Those with serious symptoms may isolate themselves to the point that they rarely leave their home.
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Is the Holy Grail for Treating Chronic Back Pain Within Reach?
UCSF neurologist Dr. Shirvalkar studies nerve-to-brain connections to find new ways to treat chronic back pain.
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UCSF Study on CTE Seeks Living Athletes’ Data to Help Diagnose the Degenerative Disease
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If Anti-Seizure Meds Don’t Work for Epilepsy, Can Surgery Help?
Vikram Rao, director of the UCSF Epilepsy Center, discusses why a third of seizure patients don’t respond to medication and the promising new surgical and technological treatments available.
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These Cells Have Hidden Powers That Could Heal Brain Injuries
UCSF scientists discovered that an overlooked cell type in the brain plays a central role in healing traumatic brain injury. Understanding how it does this will lead to treatments for injuries that currently have only minimal interventions.
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Scientists Look to Commercial Dyes to Help them Diagnose Dementia
A study screened dyes found in textiles and in the laser industry that can be used in imaging for preclinical studies to diagnose and differentiate between neurodegenerative diseases. Currently, dyes used in mouse studies cannot distinguish between different types of dementia.
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Dr. Sanjay Gupta Explores New Ways to Treat Pain
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Bruce Willis’ Personality Changes Key to Dementia Diagnosis: UCSF Expert
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From Chronic Pain to Parkinson’s, 4 Ways DBS is Changing Care
UCSF looks back on four ways it pioneered deep brain stimulation with the help of federal funding, helping patients with Parkinson’s Disease, chronic pain, depression, and more.
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This Protein Slows the Aging Brain, and We Know How to Counter It
Scientists discover a protein that gets concentrated in the brain during aging, leading brain connections to wither and cognitive decline to accelerate - and a way to counter its effects.
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Treating Chronic Pain is Hard. An Experimental Approach Shows Promise.
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Two UCSF Researchers Are Named Pew Latin American Fellows
Two new Pew Latin American fellows, Beatriz De Moraes, PhD, and Lilian Gomes de Oliveira, PhD, will each receive a $30,000 annual stipend for two years to support their work at the crossroads of immunology and neuroscience.
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Pandemic Aged Our Brains Faster, Whether or Not We Got COVID, Study Says
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Meet the Little Brain Region that Helps You Say What’s on Your Mind
Researchers discovered that a different part of the brain handles stringing sounds and words together into coherent sentences. The information could help people who have had strokes and lost the ability to create sentences.
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These Immune Cells Eat Molecular Trash to Keep Alzheimer’s at Bay
Microglia, a type of brain immune cell, can gobble up amyloid beta protein, which clumps together into toxic aggregates during Alzheimer's disease.
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Do These Two Cancer Drugs Have What It Takes to Beat Alzheimer’s?
Scientists at UCSF and Gladstone Institutes have identified cancer drugs that promise to reverse the changes that occur in the brain during Alzheimer’s, potentially slowing or even reversing its symptoms.
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Tailored Deep Brain Stimulation Improves Walking in Parkinson’s
For patients with Parkinson's disease, changes in their ability to walk can be dramatic. “Parkinson’s gait,” as it is often called, can include changes in step length and asymmetry between legs. This
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A CRISPR Approach to Neurodegenerative Diseases
The Byers Award recognizes outstanding research by faculty members in the middle of their careers. Martin Kampman’s honorary 2025 lecture is titled “A CRISPR approach to neurodegenerative diseases.”
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Visual Migraine Symptoms Linked to Tiny Brain Lesions
Visual auras, like those that occur in migraines, may be signs of small injuries to the brain’s visual cortex, according to a clinical trial at UC San Francisco that tracked the appearance of these
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Why Do Some Brain Regions Resist Alzheimer’s?
It’s been recognized for some time that Alzheimer’s disease affects brain regions differently and that tau — a protein known to misbehave — plays an important role in the disease. Normally, tau helps
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UCSF Leads Statewide Efforts to Improve Dementia Care, Diagnosis
A critical step in meeting the needs of the growing aging population is early recognition of cognitive decline. In California, women who live to be 65 or older have a one in four chance of developing
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Can Music Benefit Our Brains?
An expert in cognitive neuroscience shares the ways that music may help flex our neurons, plus her top tips for a music-filled life.
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Why Is Discovery Research So Important?
Neuroscientist Grae Davis, PhD, unpacks why public understanding of science matters.
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How Serious is Your Brain Injury? New Criteria Will Reveal More
After more than 50 years, the assessment of traumatic brain injuries gets an overhaul. Clinicians say the proposed framework will lead to more accurate diagnoses and treatment, providing more rigorous care for some patients and preventing premature discussions about halting life support in others.
