A CRISPR Approach to Neurodegenerative Diseases
The Byers Award recognizes outstanding research by faculty members in the middle of their careers. Martin Kampman’s honorary 2025 lecture is titled “A CRISPR approach to neurodegenerative diseases.”
University of California San Francisco
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Visual Migraine Symptoms Linked to Tiny Brain Lesions
Visual auras, like those that occur in migraines, may be signs of small injuries to the brain’s visual cortex, according to a clinical trial at UC San Francisco that tracked the appearance of these
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Why Do Some Brain Regions Resist Alzheimer’s?
It’s been recognized for some time that Alzheimer’s disease affects brain regions differently and that tau — a protein known to misbehave — plays an important role in the disease. Normally, tau helps
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UCSF Leads Statewide Efforts to Improve Dementia Care, Diagnosis
A critical step in meeting the needs of the growing aging population is early recognition of cognitive decline. In California, women who live to be 65 or older have a one in four chance of developing
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Can Music Benefit Our Brains?
An expert in cognitive neuroscience shares the ways that music may help flex our neurons, plus her top tips for a music-filled life.
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Why Is Discovery Research So Important?
Neuroscientist Grae Davis, PhD, unpacks why public understanding of science matters.
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How Serious is Your Brain Injury? New Criteria Will Reveal More
After more than 50 years, the assessment of traumatic brain injuries gets an overhaul. Clinicians say the proposed framework will lead to more accurate diagnoses and treatment, providing more rigorous care for some patients and preventing premature discussions about halting life support in others.
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A New System Aims to Save Injured Brains and Lives
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How Do Middle-Aged Folks Get Dementia? It Could Be These Proteins
UCSF researchers have found clues about how frontotemporal dementia develops that could lead to new diagnostics and get more patients into clinical trials.
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How ‘Magic Mushrooms’ Could Help Parkinson’s Disease Patients
A first-of-its-kind study tested the safety of psilocybin on patients with mild to moderate Parkinson’s disease and found that patients experienced clinically significant improvements in mood, cognition, and motor function that lasted for weeks after the drug was out of their systems.
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Breakthrough Multiple Sclerosis Therapy by UCSF Doctor Transforms Treatment for Millions
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Bay Area Patients Among First in U.S. To Receive Life-Changing Parkinson’s Treatment
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Stephen Hauser Wins Breakthrough Prize for Role in Redefining MS
Neuro-immunologist Stephen Hauser, MD, whose maverick thinking transformed the treatment landscape for patients with multiple sclerosis (MS), has received the 2025 Breakthrough Prize in Life Sciences.
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How Your Brain Manages Cholesterol Could Increase Alzheimer’s Risk
Alzheimer’s disease is characterized by a host of recognizable cognitive symptoms, but many non-cognitive symptoms like changes in sleep, anxiety and depression can be early signs of the disease.
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Is Increased Sleepiness in Our 80s Tied to Higher Dementia Risk?
A study followed the sleep patterns of older female participants to see if specific patterns of change were associated with a higher risk of dementia. The participants, whose average age was 83, were monitored by wrist devices that track movement and time spent asleep.
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NIH Funding Drives UCSF’s Pursuit of Better Health for All
UCSF received $815 million in awards from the National Institutes of Health (NIH) last year for research that will improve the lives of patients in the U.S. and around the world.
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How a Paralyzed Man Moved a Robotic Arm with His Thoughts
A paralyzed man was able to move a robotic arm and fingers simply by imagining himself doing so, with the help of brain signals decoded through a computer.
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The ‘Silent’ X Chromosome Gives the Aging Female Brain a Boost
Why do women's brains fare better in aging than men's? A study found that the second, 'silent' X chromosome turns on in the brain of old female mice and improves learning and memory – opening new paths to slow the decline in men and women.
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How to Build Bold Thinking to Foster Scientific Breakthroughs
Martin Kampmann, PhD, and Anna Victoria Molofsky, MD, PhD, are the 2025 recipients of the Bowes Biomedical Investigator award, which supports scientists who take novel approaches and have the potential to make significant contributions to biomedicine. Recipients receive $1.25 million over five years.
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Aging Women’s Brain Mysteries Are Tested in Trio of Studies
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Napping More as You Get Older? Here’s Why That May Not Be a Good Thing
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Human Chromosomes Evolved at Hyperspeed to Give Us Better Brains
How did humans evolve brains capable of complex language, civilization, and more? Scientists at UC San Francisco recently found that parts of our chromosomes have evolved at breakneck speeds to give us an edge in brain development compared to apes.
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This New Treatment Can Adjust to Parkinson’s Symptoms in Real Time
The FDA has approved an adaptive deep brain stimulation (aDBS) treatment for people with with Parkinson’s disease, making this groundbreaking technology available to people nationwide.
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Jumbled Proteins Paint a Bold Target on the Backs of Brain Tumors
UCSF scientists have found that some cancers, like brain cancer, make unique, jumbled proteins that make them stand out. These newly recognized cancer-specific proteins, or antigens, could speed the development of potent immunotherapies that recognize and attack hard-to-treat tumors.
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‘Healthy’ Vitamin B12 Levels Not Enough to Ward Off Neuro Decline
A study found that B12 requirements may be too low for some people, putting them at risk for cognitive decline.
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How a UCSF Scientist Helped Ban a Chemical Connected to Parkinson’s
A new EPA ban on TCE, a common industrial cleaning agent and contaminant, begins this year. UCSF’s Samuel Goldman, who led groundbreaking research to link TCE to Parkinson’s Disease, talks about the health risks.
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Delayed REM Sleep Could Be an Early Sign of Alzheimer’s
Delayed REM sleep was found to be linked to higher Alzheimer’s risk. Healthy sleep habits and treatments may help mitigate risks.
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Could Brain Aging Be Mom’s Fault?
Researchers found that female mice using only maternal X chromosomes showed faster cognitive decline, which could help explain the variation in brain aging between the sexes.
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For Women With MS, Mobility Takes Step Backward at Menopause
A new study found that menopause can speed up the progression of multiple sclerosis (MS), affecting mobility and cognitive ability.
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Genes That Grow a Healthy Brain Could Fuel Adult Glioblastoma
A new study paints one of the most detailed pictures of human brain development to date, opening the door to new tests and therapies, including for brain disorders such as autism.
