3-D Imaging Reveals Secrets of Immune Cells’ Agility
Newly developed microscopy techniques have allowed UC San Francisco researchers to observe white blood cells in action in unprecedented detail.
University of California San Francisco
Give to UCSFNewly developed microscopy techniques have allowed UC San Francisco researchers to observe white blood cells in action in unprecedented detail.
Researchers at UCSF have identified specific gut microbes associated with MS in human patients, showing that these microbes take part in regulating immune responses in mouse models of the disease.
Research team led by University of California scientists has used a modified version of the gene-editing technique CRISPR to find enhancers by prompting them into action.
A study headed by UCSF researchers fuels the probiotics debate by finding that there is no clear evidence that a supplement of the “friendly” bacteria strain of lactobacillus prevents eczema.
A virus hiding quietly in the gut may trigger the onset of a severe complication known as graft-versus-host disease (GvHD) in patients who receive bone marrow transplants.
Whether a melanoma patient will better respond to a single immunotherapy drug or two in combination depends on the abundance of certain white blood cells within their tumors, according to a new study.
A genome sequencing test developed at UCSF that can rapidly pinpoint the cause of a bacterial, viral, fungal or parasitic infection is now available to help physicians nationwide diagnose cases.
Immune cells in the brain trigger overeating and weight gain in response to diets rich in fat, according to a new study in mice led by researchers from UCSF and the UW Medical Center.
In experiments in mice, UC San Francisco researchers have discovered that regulatory T cells, directly trigger stem cells in the skin to promote healthy hair growth.
How T cells feel out intruders rapidly and reliably enough to nip infections and other threats in the bud has remained a mystery to researchers.
UCSF researcher Grant Dorsey received federal funding for the Program for Resistance, Immunology, Surveillance and Modeling of Malaria in Uganda.
UCSF researchers have helped to identify the three evolutionary steps the polio virus used to evolve from harmless vaccine into a regional menace. With the new knowledge, they have developed a new polio vaccine that should be unable to escape and cause outbreaks.
Researcher Annesa Flentje is looking at ways stress among sexual minorities – those whose sexual orientation, identity or practices differ from the majority – can affect physical and mental health, starting at the genetic level, with a particular focus of late on the effect of stress on HIV-positive men.
The mammalian placenta is a sort of armored car protecting a developing fetus. All manner of infectious agents attempt to break in, but few of them can. Scientists are working to understand why some infections do break through and how to stop them.
A type of herpes virus that infects about half of the U.S. population has been associated with risk factors for type 2 diabetes and heart disease in normal-weight women aged 20 to 49.
New research has found that successful cancer immunotherapy appears to depend on whether the treatment can trigger a system-wide immune response, rather than just a local response within the tumor itself.
UC San Francisco scientists have formed an innovative research alliance with three global pharmaceutical companies.
People with bipolar disorder, schizophrenia and major depression with psychosis may be up to 15 more likely than the general population to be HIV positive, but are only marginally more likely to be tested for the virus.
A newly identified bacterial protein that is shown to jump-start infection may be the culprit in a foodborne disease that strikes pregnant women in disproportionately high numbers, leading to miscarriage and pre-term birth.
In findings that show the effectiveness of a new strategy for treating multiple sclerosis, researchers are reporting positive results from three large, international, multicenter Phase III clinical trials of the investigational drug ocrelizumab in both relapsing multiple sclerosis and primary progressive multiple sclerosis.
Stories about sensory processing disorder, videos about “zombie” cancer cells, and news about the effects of caffeine and alcohol on the heart were among the topics that most engaged our readers in 2016.
UCSF-led research team identified the rare genetic mutation responsible for a unique case of severe combined immunodeficiency, a deadly immune system disorder also known as “boy in the bubble” disease.
UCSF researchers identified fetal brain tissue cells that are targeted by the Zika virus and determined that azithromycin can prevent the virus from infecting these cells.
UCSF researchers are learning more about what guides the formation of crystals that malaria parasites leave behind so they can work toward new treatments.
Graduate student Lauren Rodda captured a microscopic mage of a mouse gut, which highlights her work to understand the germinal center, where immune cells compete to be the best at recognizing an invading pathogen.
Researchers at UCSF and the academically affiliated Gladstone Institutes have used a newly developed gene-editing system to find gene mutations that make human immune cells resistant to HIV infection.
UCSF has ranked as one of the top 20 universities in the world, according to the 2017 Best Global Universities rankings released Tuesday by U.S. News & World Report.
Lenore Pereira, a virologist and professor in School of Dentistry’s Department of Cell and Tissue Biology, is in the middle of crucial research to understand how the mosquito-borne Zika virus harms the babies of women infected during pregnancy.