Archive: Recurrent Brain Cancers Follow Distinctive Genetic Paths
A team led by scientists from UCSF has discovered that recurrent gliomas may have genetic profiles that are markedly different from those of the initial tumors that spawned them.
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Archive: New Link Between Obesity, Early Decline in Kidney Function
A new UCSF-led study of nearly 3,000 individuals links obesity to the development of kidney disease.
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Archive: Minorities’ Health Would Benefit Most from Beverage Sugar Tax, UCSF Researchers Report
Taxing sugar-sweetened beverages is likely to decrease consumption, resulting in lower rates of diabetes and heart disease, and these health benefits are expected to be greatest for the low-income, Hispanic and African-American Californians who are at highest risk of diabetes, according to a new analysis led by researchers at UC San Francisco.
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Archive: Research Shows How Household Dogs Protect Against Asthma, Infection
Children’s risk for developing allergies and asthma is reduced when they are exposed in early infancy to a dog in the household, and now researchers have discovered a reason why.
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Archive: Researchers Link Obesity with Kidney Problems
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Archive: UCSF Research Connects Mono Lake, Evolution, and Cardiovascular Health
UCSF biochemist Daniel Minor's research suggests that "Mono Lake contains biological blueprints mirrored in our very bodies."
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Archive: UCSF Faculty Research Influences Women's Health Law
Women's reproductive health experts Diana Taylor and Tracy Weitz conducted the foundational research on the safety and quality of aspiration abortions that now has become law of the land in California.
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Archive: Molecular Sensor Detects Early Signs of Multiple Sclerosis, Gladstone Study Finds
Scientists at the UCSF-affiliated Gladstone Institutes have devised a new molecular sensor that can detect MS at its earliest stages, even before the onset of physical signs.
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Archive: Cardiovascular Study Gets Approval from the American Heart Association
UC San Francisco’s Health eHeart Study – an ambitious technology-based cardiovascular research study – has garnered the support from the American Heart Association, the largest U.S. non-profit organization dedicated to reducing disability and deaths caused by cardiovascular disease and stroke.
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Archive: UCSF 'Unusual Thinkers' Spotlight Technology's Impact on Health Care
Technology and health care often go hand in hand, and UC San Francisco highlighted this budding alliance at the 11th annual Dreamforce conference, hosted by cloud computing giant Salesforce.com.
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Archive: Structure of Key Pain-Related Protein Unveiled
In a technical tour de force, UCSF scientists have determined, at near-atomic resolution, the structure of a protein that plays a central role in the perception of pain and heat.
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Archive: Specific Heart Contractions Could Predict Atrial Fibrillation
A commonly used heart monitor may be a simple tool for predicting the risk of atrial fibrillation, the most frequently diagnosed type of irregular heart rhythm, according to researchers at UCSF.
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Archive: Article Examines Non-Physician Clinician and Industry Interactions
Quinn Grundy, a PhD student in the UCSF School of Nursing's Health Policy program recently published a systematic review in PLoS Medicine with UCSF's Lisa Bero and Ruth Malone titled: "Interactions Between Non-Physician Clinicians and Industry: A Systematic Review."
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Summiting the Precision Medicine Mountain
Top thinkers gather at UCSF to help make the new field a reality.
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Archive: Electronic Cigarettes: New Route to Smoking Addiction For Adolescents
In the first study of its kind, UCSF researchers found that youth using e-cigarettes were more likely to be trying to quit, but also were less likely to have stopped smoking and were smoking more, not less.
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Archive: UCSF wins $89 million to study anal cancer
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Archive: UCSF Scientist Wins $89M Grant to Study Anal Cancer In HIV-Infected People
A UCSF investigator has won an eight-year grant from the National Cancer Institute for a major investigation into anal cancer, a debilitating and sometimes fatal disease largely concentrated among people with HIV.
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Archive: Scientists Pinpoint Cell Type and Brain Region Affected by Gene Mutations in Autism
A team led by UCSF scientists has identified the disruption of a single type of cell – in a particular brain region and at a particular time in brain development – as a significant factor in the emergence of autism.
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Archive: Drug Strategy Blocks a Leading Driver of Cancer
The protein in cells that most often drives the development of cancers has eluded scientists’ efforts to block it for three decades — until now.
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Archive: UCSF Researcher Identifies Key to Energy-Burning Brown Fat
Current anti-obesity treatments include strategies to prevent food energy from being absorbed, such as orlistat, which prevents fat absorption from food.
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Archive: Birth Control Linked With Higher Glaucoma Risk
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The Gene Machine
Precision Medicine Pillar No. 5: Omics Medicine. Molecular biologist Nevan Krogan's work is not only illuminating how genes and proteins function, it's also shedding light on the underlying biology of disease for each person.
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A Digital Path to Health
Precision Medicine Pillar No. 6: Digital Health. The Center for Digital Health Innovation shepherds the development of digital health innovations created at UCSF and validates the effectiveness of devices from both inside and outside the institution.
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Big Data, Tailored Care
Precision Medicine Pillar No. 3: Clinical Discovery. Researchers are taking vast amounts of patient data, often collected through first-ever clinical studies, and putting it into tools like MS Bioscreen that have a direct impact on patient care.
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The Fabric of Disease
Precision Medicine Pillar No. 4: Computational Health Sciences. Computationally intensive approaches are used to analyze and cross-analyze large but discrete collections of data, such as patient health histories and genetic makeup.
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Digging Deeper Into Cancer
Precision Medicine Pillar No. 2: Basic Discovery. The long path to developing potent new treatments often starts with an observation in the lab that then leads to a question about a fundamental life process.
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It’s All About Networking
Precision Medicine Pillar No. 1: Knowledge Network. With an increased ability to harvest information automatically and more powerfully, scientists can find the connections among discoveries that would otherwise go unrecognized.
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Archive: Fast-Mutating DNA Sequences Shape Early Development; Guided Evolution of Uniquely Human Traits
Researchers at the UCSF-affiliated Gladstone Institutes have discovered how the activation of specific stretches of DNA control the development of uniquely human characteristics.
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Archive: Scientists Halt Deadly Organ Tissue Scarring in its Tracks
UCSF scientists were able to arrest, and even reverse, tissue scarring of the liver, kidneys and lungs in mice. The scarring, also known as fibrosis, is a major factor in nearly half of all deaths in developed countries.
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Archive: Did Inefficient Cellular Machinery Evolve to Fight Viruses and Jumping Genes?
When it comes to genes, a UCSF scientist wants to turn conventional wisdom about human and bacterial evolution on its head.