Archive: Prop. 47 Lessened Racial Disparities in Drug Arrests
UCSF researchers quantified the effects of Prop 47, which reclassified drug possession offenses from felonies or “wobblers”.
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Archive: Not Junk: ‘Jumping Gene’ is Critical for Early Embryo
A so-called “jumping gene” that researchers long considered either genetic junk or a pernicious parasite is actually a critical regulator of the first stages of embryonic development.
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Archive: CryoEM Study Captures Opioid Signaling in the Act
Scientists have used ultra-high-resolution cryo–electron microscopy to capture the most detailed portrait ever of an opioid drug triggering the biochemical signaling cascade that gives it its power.
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Archive: Deaths from Cardiac Arrest Are Misclassified, Overestimated
Forty percent of deaths attributed to cardiac arrest are not sudden or unexpected, and nearly half of the remainder are not arrhythmic – the only situation in which CPR and defibrillators are effective.
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Archive: Electrically Stimulating the Brain May Restore Movement After Stroke
UCSF scientists have improved mobility in rats that had experienced debilitating strokes by using electrical stimulation to restore a distinctive pattern of brain cell activity associated with efficient movement.
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Archive: Diabetes Added to High Risks for People with Severe Mental Illness
People with severe mental illness are more than twice as likely to have Type 2 diabetes, with even higher risks among patients who are African American or Hispanic, according to a new study led by UCSF.
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Archive: Opioid Crisis: This Doctor’s Street-Level Views Could Change the Course of the Epidemic
A staggering 64,000 people in the United States died in 2016 from drug overdoses – and a study led by UCSF’s Daniel Ciccarone is aiming to get at the heart of of the problem, including by interviewing opioid users.
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NPR’s Nerdette: “I Have A Rare Genetic Disease. CRISPR Might Fix It.”
As a kindergartener, Nerdette co-host Greta Johnsen was diagnosed with an eye condition that is among the best diseases for experimenting with the gene editing tool CRISPR. This episode follows Greta, her father, and UCSF geneticist and Gladstone Institutes investigator Bruce Conklin, MD, as he tries to develop the perfect CRISPR system to remove the faulty DNA from Johnsen’s eye cells.
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Archive: Frequent Use of the ER Fell After the Affordable Care Act
The odds of being a frequent user of California’s emergency departments dropped in the two years following the implementation of major provisions of the Affordable Care Act in January 2014.
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Archive: Binging, Purging and Fasting More Common in Overweight, Obese Young Adults
Young adults who are overweight or obese are twice as likely as their leaner peers to binge and purge, use laxatives or diuretics, or force themselves to vomit as a means of controlling their weight.
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Startup Science
Silicon Valley is helping researchers like Wendell Lim move basic science breakthroughs into translational applications, making treatments available to patients faster than normally possible.
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2018: A Drug Odyssey
The journey from discovering and developing effective, precise medications to using them correctly and safely in patients is hardly fast and easy. Nor is it a straight shot. Scientists in the UCSF School of Pharmacy are challenging the status quo every step of the way.
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Streets of Pain
UCSF public health researcher Daniel Ciccarone, MD, shares his quest to understand the nation’s opioid epidemic, one user at a time.
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Archive: Electric ‘Sixth Sense’ Evolved Differently in Sharks and Skates
UCSF researchers have discovered that shark and skate electrosensory systems have distinct specializations that match how the animals use their electrical sense in the wild.
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Archive: Study Reveals Brain Activity Patterns Underlying Fluent Speech
The new research reveals that the brain’s speech centers are organized more according to the physical needs of the vocal tract as it produces speech than by how the speech sounds.
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Archive: Synthetic ‘Tissues’ Build Themselves
Researchers have demonstrated the ability to program groups of individual cells to self-organize into multi-layered structures reminiscent of simple organisms or the first stages of embryonic development.
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Archive: Doctors Fail to Flag Concussion Patients for Critical Follow-Up
Nationwide study found that more than half of the patients diagnosed with concussion, may fall off the radar shortly after diagnosis, placing in jeopardy treatments for long-term effects.
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Archive: Gut Bacteria Produce a Special Enzyme To Protect Us from Plant Toxins
A UCSF researcher is among scientists who discovered the specific bacterial enzyme found in the human gut that can render a common heart drug ineffective.
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Archive: Risk of Preterm Birth Reliably Predicted by New Test
Scientists at UCSF have developed a test to predict a woman’s risk of preterm birth when she is between 15 and 20 weeks pregnant.
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Archive: Using Facebook to Help Young Adults Quit Smoking
Smoking cessation intervention for young adults conducted on Facebook found smokers are 2.5 times more likely to quit with the Facebook-based treatment than if they were referred to an online program.
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Archive: Challenges for Adoption of New Genetic Tests Outlined in New Research
Every day, on average, 10 new genetic tests become commercially available to help doctors and patients make more informed decisions about health care. Yet few doctors know how to navigate the tens of thousands of tests that populate the genetic testing marketplace, which prevents patients from benefiting from them.
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Archive: Deep Space Radiation Treatment Reboots Brain’s Immune System
UCSF neuroscientist identified the first potential treatment for the brain damage caused by exposure to cosmic rays.
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Archive: Women Sometimes Feel Regret After Electing to Freeze Their Eggs
Most women feel empowered by elective procedures that enable them to bank eggs in case they can’t conceive naturally later in life, but one in six become regretful.
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Archive: Yanny Vs. Laurel: A Neuroscientist Weighs In
Matthew Leonard, who studies the neural basis of word representations, weighs in with a scientific perspective on the debate about “Laurel” versus “Yanny.”
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Archive: Lyme Disease is On the Rise – An Expert Explains Why
Infectious disease expert Charles Chiu explains the rise in Lyme disease cases, better diagnostic tests on the horizon and what you need to know to protect yourself from infection.
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Archive: Body’s 'Natural Opioids' Affect Brain Cells Much Differently than Morphine
Study led by UCSF scientists shows that brain cells react differently to opioid substances created inside the body than they do to purely synthetic opioid drugs.
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Archive: Living in Better Neighborhood May Protect Health of Kids in Poverty
UCSF study has found that simply living in a more desirable neighborhood may act as a health booster for low-income children.
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Archive: Dementia Risk Doubles Following Concussion, UCSF Study Shows
Dementia is a possible complication following a concussion, even if the patient did not lose consciousness.
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Archive: UCSF Researcher’s 20 Years Chasing the Genetic Roots of Asthma
Esteban Burchard, who arrived at UCSF in 1998, marks the 20th year of his asthma project in May. His lab, which he named the UCSF Asthma Collaboratory, has delved deep into the genetic basis of asthma and of drug response in the disease.
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Archive: Liver Cells Switch Identities to Grow New Tissue
By studying a rare liver disease called Alagille syndrome, scientists from UC San Francisco and Cincinnati Children’s Hospital Medical Center have discovered the mechanism behind an unusual form of tissue regeneration that may someday reduce the need for expensive and difficult-to-obtain organ transplants.