Scientists Discover How Multiple Sclerosis Kills Neurons
Researchers discover that the nerve cells that make us uniquely human are also uniquely vulnerable to dying during the waves of inflammation that occur in multiple sclerosis.
University of California San Francisco
Give to UCSFResearchers discover that the nerve cells that make us uniquely human are also uniquely vulnerable to dying during the waves of inflammation that occur in multiple sclerosis.
A special program developed by the University of California Health system and adopted at all six UC academic medical centers has been effective in reducing hypertension in patients and could be used by other health systems looking to standardize chronic disease care.
Why are the elderly so much more likely to get sick and hospitalized for pneumonia and COVID? UCSF scientists found that old lung cells overreact to infections, inviting immune attack and runaway inflammation.
Forty-four UC San Francisco scientists have been named to the annual list of most “Highly Cited Researchers” for 2025 by the analytics company Clarivate.
TRPM8, a key cold-sensing protein in nerve cells, activates to send “cold” signals to the brain when exposed to low temperatures or cooling sensations like menthol. New research from UCSF reveals how TRPM8 changes shape in response to cold, offering insights into cold sensitivity, pain conditions, and why birds are less sensitive to cold than mammals.
A new study traces the molecular pathway connecting the gut immune system to the brain during a parasitic infection, explaining how the immune system triggers a loss of appetite.
New research pits psychedelic-assisted therapy against traditional antidepressants in an unblinded study that presents a sobering viewpoint on the treatment's potential.
Poor sleep is associated with an increased risk for dementia, but many sleep studies have had inconsistent results. For the first time, used AI to analyze tiny electrical signals in the brain of 7,000 participants healthy participants to calculate “brain age." They find that dementia risk increases significantly when the brain age exceeds actual age.
UCSF scientists found a precise way to turn on cancer-fighting immune cells inside the body. This more potent form of CAR-T has the potential to treat many more cancers.
Heart disease is the leading cause of adult death worldwide, making cardiovascular disease diagnosis and management a global health priority. An echocardiogram, or cardiac ultrasound, is one of the
Azithromycin was used early in the pandemic to treat COVID-19 in patients and has continued to be used to fight respiratory illnesses. But a new UCSF-led study supports findings that show it isn't effective and that it has negative consequences.
The American Academy of Orthopaedic Surgeons (AAOS) has awarded the 2026 New Emerging eXperts in Translational Science (NEXT) Award to Kelsey H. Collins, PhD, for her research on the role that fat
Scientists at UCSF invented a microscopic “womb” material for growing artificial organs (organoids) from scratch.
A UCSF team discovers that a notorious cancer-causing enzyme called SRC exists on the outside of many tumors - so they're turning it into a cancer drug.
UCSF environmental epidemiologist and toxicologist Matthew Gribble, PhD, was named by The Pew Charitable Trusts as the 2026 recipient of the Pew-Hoover Fellowship in Marine and Biomedical Science.
UCSF received $824 million from the National Institutes of Health (NIH) in 2025 to drive the discovery, translational, and clinical science that leads to new treatments for disease and advances U.S. leadership in health and science.
UCSF has been named a Top Producing Institution for Fulbright U.S. Scholars for the 2025-2026 academic year. Quick highlight of the four winners.
In a partnership between the UCSF School of Nursing and UCSF Health, nursing experts are mentoring UCSF Health bedside nurses on projects, resulting in improvements in patient care and in how nurses work at UCSF Health.
UCSF researcher Daniel Mathalon, MD, PhD, believes that burgeoning knowledge about biomarkers — biological measures of a medical condition that also serve as markers of treatment effectiveness — could help intercept schizophrenia.
UCSF Health’s Adult Congenital Cardiology Program has earned accreditation from the Adult Congenital Heart Association (ACHA), recognizing UCSF’s dedication to providing high-quality, patient-centered
A study finds that while sunscreen costs hugely vary, lower-cost lotions can be just as effective in protecting against the sun.
Tau proteins play an important role in our normal brain function, mainly by helping to stabilize neurons in the brain. But in Alzheimer’s disease, tau proteins can misfold and tangle inside neurons.
An NIH-funded survey by UCSF researchers found that despite the fact that digital health will continue to be core in health delivery, less than half of surveyed health systems are checking for barriers to using patient portals, telemedicine, and other digital health tools.
A UCSF team finds a liver protein, released with exercise, that improves memory in aging and Alzheimer’s disease by repairing the brain’s blood vessels. It's the missing link between exercise and brain rejuvenation that many have been hunting for.
UCSF researchers found that 64.4% of female patients report sickle cell disease (SCD) pain during menstruation. However, these patients also report low rates of hormonal contraceptive awareness or use, which could potentially help treat SCD pain for female patients.