Archive: A New Insight into Parkinson’s Disease Protein
New research by UCSF neuroscientist Robert Edwards has uncovered the role alpha-synuclein plays in the normal brain. The protein has long been implicated in Parkinson’s disease.
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Archive: Research Aims to Shape More Precise Treatments for Depression in Women
Interim Dean Sandra Weiss of the UCSF School of Nursing is leading three major studies aimed at shedding important light on some of the most pressing issues facing American women with depression and the clinicians who treat them.
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What Do Our Genes Have to Do With Sleep?
Ying-Hui Fu, a UCSF professor of neurology and a pioneer in the study of sleep and genetics, explains the science behind strange sleep patterns and shares why shut-eye is more important than you think.
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Archive: Next-Gen Precision Diagnostics Now Available at UCSF
A genome sequencing test developed at UCSF that can rapidly pinpoint the cause of a bacterial, viral, fungal or parasitic infection is now available to help physicians nationwide diagnose cases.
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Drug Reverses Memory Failure Caused by Traumatic Brain Injury
UCSF scientists used an experimental drug to completely reverse severe learning and memory impairments caused by traumatic brain injury in mice.
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Archive: Elevated Rate of Autism Symptoms Found in Children with Tourette Syndrome
Around one in five children with Tourette syndrome, a neurological disorder characterized by involuntary movements and vocalizations, met criteria for autism in a study headed by UCSF.
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Archive: Chronic Pain Linked to Increased Risk of Dementia in Study of Older Adults
Researchers at UCSF have found that older people with persistent pain show quicker declines in memory as they age and are more likely to have dementia years later.
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Archive: Research Reveals How RNA Gums Up Cell Nucleus in Huntington’s, Other Neurodegenerative Disorders
UCSF researchers have drawn a link between genetic abnormalities in neurodegenerative diseases and the formation of RNA foci, work the scientists said may open avenues to the development of new drug treatments.
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Archive: First Clear-Cut Risk Genes for Tourette Disorder Revealed
Researchers made a significant advance, identifying the first “high-confidence” risk gene for Tourette disorder as well as three other probable risk genes.
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Archive: Cognitive Decline After Surgery Tied to Brain’s Own Immune Cells
After undergoing surgery, elderly patients often experience cloudy thinking. Mounting evidence suggests that heightened inflammation in the brain following surgery is the more likely cause.
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Archive: New Multiple Sclerosis Drug, Backed by 40 Years of Research, Could Halt Disease
A newly approved drug that is the first to reflect the current scientific understanding of multiple sclerosis is holding new hope for the hundreds of thousands Americans living with the disease. It also highlights the importance of clinician scientists like UCSF’s Stephen Hauser who are working to transform research into cures for patients.
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Archive: F.D.A. Approves First Drug to Treat Severe Multiple Sclerosis
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Archive: Distinguishing Between Dementia and Depression with Neuroimaging
Neuroimaging is helping to distinguish between depression and dementia – two diseases with overlapping symptoms that can be difficult to diagnose properly.
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Archive: Science in Focus: Creating Neurons from Skin Cells to Understand Autism
Studying brain disorders is complicated for many reasons, not the least being the ethics of obtaining living neurons. To overcome that obstacle, UCSF postdoc Aditi Deshpande is starting with skin cells.
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Archive: Zebrafish-to-Patient Approach Speeds Search for Childhood Epilepsy Treatments
In an unprecedented leap from lab to patients, a potential treatment for childhood epilepsy identified in experiments with zebrafish.
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Archive: Artificial Intelligence Aids Scientists in Uncovering Hallmarks of Mystery Concussion
New research is paving the way to a precision medicine approach to the diagnosis and treatment of patients with traumatic brain injury.
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Archive: Poor Odor Identification May Be Early Warning for Dementia
Poor performance on a simple odor identification test was associated with a significantly increased risk of developing dementia years later.
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Archive: Autism Researchers Discover Genetic ‘Rosetta Stone’
Distinct sets of genetic defects in a single neuronal protein can lead either to infantile epilepsy or to autism spectrum disorders.
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Archive: Therapy for Abnormal Heartbeats May Cause Brain Injury
A common treatment for irregular heartbeats known as catheter ablation may result in the formation of brain lesions when it is performed on the left side of the heart.
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Archive: UCSF, Pfizer Renew Research Collaboration, Citing Progress in Drug Discovery Research
UC San Francisco and Pfizer Inc.’s Centers for Therapeutic Innovation have renewed an agreement to identify and develop biologic compounds against both known and novel targets.
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Archive: Positive Multiple Sclerosis Clinical Trial Results Support New Treatment Approach
In findings that show the effectiveness of a new strategy for treating multiple sclerosis, researchers are reporting positive results from three large, international, multicenter Phase III clinical trials of the investigational drug ocrelizumab in both relapsing multiple sclerosis and primary progressive multiple sclerosis.
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Archive: Cutting Through the Clamor: How the Brain Helps Us Understand Spoken Words in Noisy Settings
UCSF scientists have discovered an unexpected mechanism the brain uses to seamlessly compensate when speech sounds are obscured by noise.
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Archive: Most Popular Science Stories of 2016
Stories about sensory processing disorder, videos about “zombie” cancer cells, and news about the effects of caffeine and alcohol on the heart were among the topics that most engaged our readers in 2016.
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Archive: Alzheimer’s and Concussion-Related CTE May Spread in the Brain Via Common Mechanism
A shared biological mechanism may drive the progression of both Alzheimer’s disease and chronic traumatic encephalopathy, a neurodegenerative condition associated with repeated concussions and brain trauma.
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Archive: Zika in Fetal Brain Tissue Responds to a Popular Antibiotic
UCSF researchers identified fetal brain tissue cells that are targeted by the Zika virus and determined that azithromycin can prevent the virus from infecting these cells.
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Archive: Project to Apply Artificial Intelligence to Imaging of Brain Emergencies Receives $1.2M
UCSF researchers have received $1.2 million for their work to make imaging machines smarter, so they can detect neurological emergencies and triage patients for immediate treatment.
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Archive: For Children With Brain Tumors, Next-Generation Sequencing May Lead to Different Diagnoses
Next-generation sequencing for patients at UCSF Medical Center is prompting changes in brain tumor diagnoses for some children and a retooling of treatment plans in many cases.
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Archive: Gene Links Risk of Psychiatric Disease to Reduced Synapse Numbers
Research led by UCSF scientists has revealed that mutations in a gene linked with brain development may dispose people to multiple forms of psychiatric disease by changing the way brain cells communicate.
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Archive: Human Neurons Continue to Migrate After Birth, Research Finds
Researchers at UCSF have discovered a previously unknown mass migration of inhibitory neurons into the brain’s frontal cortex during the first few months after birth.
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Archive: Replacing Myelin Protects Nerve Cells, Restores Function in Mouse Model of Multiple Sclerosis
Using a mouse model of multiple sclerosis, UCSF scientists demonstrated that regenerating myelin can both protect neurons from damage and restore lost function.