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Stephen Hauser Wins Breakthrough Prize for Role in Redefining MS
Neuro-immunologist Stephen Hauser, MD, whose maverick thinking transformed the treatment landscape for patients with multiple sclerosis (MS), has received the 2025 Breakthrough Prize in Life Sciences.
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How Your Immune System Plays Matchmaker to Find and Kill HIV
Ten UCSF graduate students presented their research in accessible, 3-minute talks at the 2025 Grad Slam event. This year’s first-place talk was by Sophia Miliotis on how our immune system uses matchmaking skills to look for signs of viruses in cells that should be destroyed.
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How Your Brain Manages Cholesterol Could Increase Alzheimer’s Risk
Alzheimer’s disease is characterized by a host of recognizable cognitive symptoms, but many non-cognitive symptoms like changes in sleep, anxiety and depression can be early signs of the disease.
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Is Increased Sleepiness in Our 80s Tied to Higher Dementia Risk?
A study followed the sleep patterns of older female participants to see if specific patterns of change were associated with a higher risk of dementia. The participants, whose average age was 83, were monitored by wrist devices that track movement and time spent asleep.
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Lo-Res to Hi-Res, A Better way to Pinpoint Where Seizures Begin
Locating seizure onset zones is a critical requirement for epilepsy surgery. This often relies upon intracranial recordings, but finding the exact zone can still present challenges. An experimental study capturing seizures on grid electrode arrays of varying density found that higher density grid arrays produced more specificity in seizure onset areas.
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NIH Funding Drives UCSF’s Pursuit of Better Health for All
UCSF received $815 million in awards from the National Institutes of Health (NIH) last year for research that will improve the lives of patients in the U.S. and around the world.
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How a Paralyzed Man Moved a Robotic Arm with His Thoughts
A paralyzed man was able to move a robotic arm and fingers simply by imagining himself doing so, with the help of brain signals decoded through a computer.
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The ‘Silent’ X Chromosome Gives the Aging Female Brain a Boost
Why do women's brains fare better in aging than men's? A study found that the second, 'silent' X chromosome turns on in the brain of old female mice and improves learning and memory – opening new paths to slow the decline in men and women.
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How to Build Bold Thinking to Foster Scientific Breakthroughs
Martin Kampmann, PhD, and Anna Victoria Molofsky, MD, PhD, are the 2025 recipients of the Bowes Biomedical Investigator award, which supports scientists who take novel approaches and have the potential to make significant contributions to biomedicine. Recipients receive $1.25 million over five years.
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Aging Women’s Brain Mysteries Are Tested in Trio of Studies
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Napping More as You Get Older? Here’s Why That May Not Be a Good Thing
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Human Chromosomes Evolved at Hyperspeed to Give Us Better Brains
How did humans evolve brains capable of complex language, civilization, and more? Scientists at UC San Francisco recently found that parts of our chromosomes have evolved at breakneck speeds to give us an edge in brain development compared to apes.
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This New Treatment Can Adjust to Parkinson’s Symptoms in Real Time
The FDA has approved an adaptive deep brain stimulation (aDBS) treatment for people with with Parkinson’s disease, making this groundbreaking technology available to people nationwide.
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Jumbled Proteins Paint a Bold Target on the Backs of Brain Tumors
UCSF scientists have found that some cancers, like brain cancer, make unique, jumbled proteins that make them stand out. These newly recognized cancer-specific proteins, or antigens, could speed the development of potent immunotherapies that recognize and attack hard-to-treat tumors.
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‘Healthy’ Vitamin B12 Levels Not Enough to Ward Off Neuro Decline
A study found that B12 requirements may be too low for some people, putting them at risk for cognitive decline.
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How a UCSF Scientist Helped Ban a Chemical Connected to Parkinson’s
A new EPA ban on TCE, a common industrial cleaning agent and contaminant, begins this year. UCSF’s Samuel Goldman, who led groundbreaking research to link TCE to Parkinson’s Disease, talks about the health risks.
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Delayed REM Sleep Could Be an Early Sign of Alzheimer’s
Delayed REM sleep was found to be linked to higher Alzheimer’s risk. Healthy sleep habits and treatments may help mitigate risks.
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Could Brain Aging Be Mom’s Fault?
Researchers found that female mice using only maternal X chromosomes showed faster cognitive decline, which could help explain the variation in brain aging between the sexes.
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I’m a Stroke Doctor. Here’s How I Reduce My Own Risk
In a Q&A, neurologist Lauren Patrick describes stroke risks and mitigation, along with personal exercise and diet changes she’s made to help prevent lower her own risk of stroke.
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For Women With MS, Mobility Takes Step Backward at Menopause
A new study found that menopause can speed up the progression of multiple sclerosis (MS), affecting mobility and cognitive ability.
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Genes That Grow a Healthy Brain Could Fuel Adult Glioblastoma
A new study paints one of the most detailed pictures of human brain development to date, opening the door to new tests and therapies, including for brain disorders such as autism.
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Treating Brain Injuries Remains Difficult. S.F. Neurosurgeon’s Trial May Spot Drugs That Help
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Why Some People Can Get Away With Only a Little Sleep Every Night
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The Future of Neuroscience: Building a Silicon Brain
A digital twin of a human mind? It isn’t science fiction.
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On the Origin of Diseases
Insights from human evolution could change how we understand and treat illness.
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The Surprising Effect of Stress on Your Brain’s Reward System
UCSF scientists are uncovering the brain mechanisms behind resilience to stress and exploring new, non-invasive treatments for depression through groundbreaking research in mice.
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48 UCSF Researchers Are Honored for Their High-Impact Science
Nearly 50 UCSF researchers have been named to Clarivate’s list of most influential scientists for 2024.
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How Optogenetics Can Put the Brakes on Epilepsy Seizures
A technique involving the use of light pulses to prevent seizure-like activity in neurons could one day become a new, non-invasive treatment for epilepsy.
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This AI Tool Helps Neurosurgeons Find Sneaky Cancer Cells
An AI-based diagnostic system reveals cancerous tissue that may not otherwise be visible during brain tumor surgery. This enables neurosurgeons to remove it while the patient is still under anesthesia – or treat it afterwards with targeted therapies.
