University of California San Francisco
Give to UCSFNeuro-immunologist Stephen Hauser, MD, whose maverick thinking transformed the treatment landscape for patients with multiple sclerosis (MS), has received the 2025 Breakthrough Prize in Life Sciences.
Ten UCSF graduate students presented their research in accessible, 3-minute talks at the 2025 Grad Slam event. This year’s first-place talk was by Sophia Miliotis on how our immune system uses matchmaking skills to look for signs of viruses in cells that should be destroyed.
Alzheimer’s disease is characterized by a host of recognizable cognitive symptoms, but many non-cognitive symptoms like changes in sleep, anxiety and depression can be early signs of the disease.
A study followed the sleep patterns of older female participants to see if specific patterns of change were associated with a higher risk of dementia. The participants, whose average age was 83, were monitored by wrist devices that track movement and time spent asleep.
Locating seizure onset zones is a critical requirement for epilepsy surgery. This often relies upon intracranial recordings, but finding the exact zone can still present challenges. An experimental study capturing seizures on grid electrode arrays of varying density found that higher density grid arrays produced more specificity in seizure onset areas.
UCSF received $815 million in awards from the National Institutes of Health (NIH) last year for research that will improve the lives of patients in the U.S. and around the world.
A paralyzed man was able to move a robotic arm and fingers simply by imagining himself doing so, with the help of brain signals decoded through a computer.
Why do women's brains fare better in aging than men's? A study found that the second, 'silent' X chromosome turns on in the brain of old female mice and improves learning and memory – opening new paths to slow the decline in men and women.
Martin Kampmann, PhD, and Anna Victoria Molofsky, MD, PhD, are the 2025 recipients of the Bowes Biomedical Investigator award, which supports scientists who take novel approaches and have the potential to make significant contributions to biomedicine. Recipients receive $1.25 million over five years.
How did humans evolve brains capable of complex language, civilization, and more? Scientists at UC San Francisco recently found that parts of our chromosomes have evolved at breakneck speeds to give us an edge in brain development compared to apes.
The FDA has approved an adaptive deep brain stimulation (aDBS) treatment for people with with Parkinson’s disease, making this groundbreaking technology available to people nationwide.
UCSF scientists have found that some cancers, like brain cancer, make unique, jumbled proteins that make them stand out. These newly recognized cancer-specific proteins, or antigens, could speed the development of potent immunotherapies that recognize and attack hard-to-treat tumors.
A study found that B12 requirements may be too low for some people, putting them at risk for cognitive decline.
A new EPA ban on TCE, a common industrial cleaning agent and contaminant, begins this year. UCSF’s Samuel Goldman, who led groundbreaking research to link TCE to Parkinson’s Disease, talks about the health risks.
Delayed REM sleep was found to be linked to higher Alzheimer’s risk. Healthy sleep habits and treatments may help mitigate risks.
Researchers found that female mice using only maternal X chromosomes showed faster cognitive decline, which could help explain the variation in brain aging between the sexes.
In a Q&A, neurologist Lauren Patrick describes stroke risks and mitigation, along with personal exercise and diet changes she’s made to help prevent lower her own risk of stroke.
A new study found that menopause can speed up the progression of multiple sclerosis (MS), affecting mobility and cognitive ability.
A new study paints one of the most detailed pictures of human brain development to date, opening the door to new tests and therapies, including for brain disorders such as autism.
A digital twin of a human mind? It isn’t science fiction.
Insights from human evolution could change how we understand and treat illness.
UCSF scientists are uncovering the brain mechanisms behind resilience to stress and exploring new, non-invasive treatments for depression through groundbreaking research in mice.
Nearly 50 UCSF researchers have been named to Clarivate’s list of most influential scientists for 2024.
A technique involving the use of light pulses to prevent seizure-like activity in neurons could one day become a new, non-invasive treatment for epilepsy.
An AI-based diagnostic system reveals cancerous tissue that may not otherwise be visible during brain tumor surgery. This enables neurosurgeons to remove it while the patient is still under anesthesia – or treat it afterwards with targeted therapies.