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Research led by scientists at the UCSF-affiliated Gladstone Institutes has identified the precise chain of molecular events in the human body that drives the death of most of the immune system’s CD4 T cells as an HIV infection leads to AIDS. Further, they have identified an existing anti-inflammatory drug that in laboratory tests blocks the death of these cells.
Children’s risk for developing allergies and asthma is reduced when they are exposed in early infancy to a dog in the household, and now researchers have discovered a reason why.
Scientists at the UCSF-affiliated Gladstone Institutes have devised a new molecular sensor that can detect MS at its earliest stages, even before the onset of physical signs.
In a technical tour de force, UCSF scientists have determined, at near-atomic resolution, the structure of a protein that plays a central role in the perception of pain and heat.
The protein in cells that most often drives the development of cancers has eluded scientists’ efforts to block it for three decades — until now.
Current anti-obesity treatments include strategies to prevent food energy from being absorbed, such as orlistat, which prevents fat absorption from food.
Precision Medicine Pillar No. 1: Knowledge Network. With an increased ability to harvest information automatically and more powerfully, scientists can find the connections among discoveries that would otherwise go unrecognized.
Researchers at the UCSF-affiliated Gladstone Institutes have discovered how the activation of specific stretches of DNA control the development of uniquely human characteristics.
UCSF scientists were able to arrest, and even reverse, tissue scarring of the liver, kidneys and lungs in mice. The scarring, also known as fibrosis, is a major factor in nearly half of all deaths in developed countries.
When it comes to genes, a UCSF scientist wants to turn conventional wisdom about human and bacterial evolution on its head.
Eleven leading scientists from the California Institute for Quantitative Biosciences (QB3) presented their latest aging research findings and anti-aging strategies at a daylong symposium called “The Science of Staying Younger Longer.”
Through support from the Catalyst Awards, UCSF researcher Aditi Bhargava is working to develop a method for delivering small-molecules to a specific target group of cells for treatment of pain.
Teams of scientists at UCSF are collaborating to build upon existing imaging techniques and find new ways to monitor diseases using creative applications of emerging technologies.
The way cells divide to form new cells – to support growth, to repair damaged tissues, or simply to maintain our healthy adult functioning – is controlled in previously unsuspected ways, UCSF researchers have discovered.
Scientific progress and innovation are speeding along, faster than ever before, but arbitrary spending cuts are posing an unprecedented threat.
