Fetal Therapy Offers Hope for Patients with Rare Genetic Disorders
Using a protocol developed at UCSF, physicians have successfully treated a fetus with a devastating genetic disorder for the first time, and the child is now thriving as a toddler.
University of California San Francisco
Give to UCSF
Can Gut Microbes Impact Chemotherapy? So Far, the Answer is ‘Yes’
Bacteria in our guts may play a significant role in the metabolism of anti-cancer drugs that are critical for treating colon cancer and other types of cancers.
Machine Learning Enables Diagnosis of Sepsis, the Elusive Global Killer
A new diagnostic method that applies machine learning to advanced genomics data from both microbe and host to identify and predict sepsis cases was developed by researchers at UCSF, the Chan Zuckerberg Initiative, and CZ Biohub.
Non-White Newborns With Cystic Fibrosis More Likely To Be Missed in Screening
Cystic fibrosis is missed more often in newborn screenings for non-white than white babies, creating higher risk for irreversible lung damage and other serious outcomes in Black, Hispanic, Asian, American Indian and Alaska Native newborns.
Fatty Liver Linked to Survival in E. Coli Infection
Scientists at UCSF have developed a new way of looking at sex-biased diseases that is rooted in evolutionary biology.
UCSF Researchers Discover How Vascular Cells Develop in Prenatal Brain
UCSF has revealed how blood vessel cells develop in the prenatal human brain, paving the way to fully understand the role of these cells in healthy brain development and disease.
Drug Turns Cancer Gene Into ‘Eat Me’ Flag for Immune System
A new therapy pulls forward a mutated version of the KRAS protein to help the immune system recognize and destroy cancer cells.
A Cellular Engineering Breakthrough: High-Yield CRISPR Without Viral Vectors
A new variation of the CRISPR-Cas9 gene editing system makes it easier to re-engineer massive quantities of cells for therapeutic applications. The approach, developed at Gladstone Institutes and UC San Francisco (UCSF), lets scientists introduce especially long DNA sequences to precise locations in the genomes of cells at remarkably high efficiencies without the viral delivery systems that have traditionally been used to carry DNA into cells.
Giving Immunotherapy Cells Resilience to Pass the ‘Stress Test’
T cells used in immunotherapy treatments can get exhausted and shut down by fighting cancer cells and tumors. Using a CRISPR-based edit on these cells’ genomes, researchers at UCSF and Gladstone Institutes have rendered the therapeutic cells more resilient against tumors.
For Checking Blood Pressure at Home, Basic Cuffs Are Just as Good
A new national study led by UCSF found that more sophisticated devices that pair with smartphones don’t lead to better blood pressure control than home-use blood pressure cuffs.
Blood Tests in Newly Brain-Injured Patients Predict Death, Severe Disability
Blood tests taken within 24 hours of a traumatic brain injury (TBI) flag which patients are likely to die and which patients are likely to survive with severe disability, according to a study headed by UCSF, the University of Pennsylvania and the University of Michigan.
Scientists Map Networks of Disease-Associated Immune Genes
A new "subway map" of immune networks connects gene variation to risk for autoimmune disease.
A Brain Tumor Patient Celebrates Survival
When Cheryl Broyles was diagnosed with glioblastoma, her goal was to outlive the disease’s 15-month prognosis. That was 22 years ago. Broyles’ survival has been the result of luck, tumor location, and cutting-edge treatment and diagnostics.
UCSF Cancer Specialists to Present Clinical Findings at Major Conference
The latest advances in cancer care and research will be showcased at the annual American Society of Clinical Oncology (ASCO) Annual Meeting, the world’s largest clinical cancer meeting.
