Small-Molecule Drug Reverses Neural Effects of Concussion
A small molecule called ISRIB that was identified at UCSF can reverse the neuronal and cognitive effects of concussion in mice weeks after an injury occurred, new research found.
University of California San Francisco
Give to UCSFA small molecule called ISRIB that was identified at UCSF can reverse the neuronal and cognitive effects of concussion in mice weeks after an injury occurred, new research found.
Johns Hopkins University and UCSF, have added new documents to the Opioid Industry Documents Archive that detail the role of retail pharmacies in the opioid overdose epidemic.
Not all senescent cells are harmful “zombies” that should be wiped out to prevent age-related disease. New research from UCSF found that some of them are embedded in young, healthy tissues and promote normal repair from damage.
A new study points to another persistent effect of COVID-19, identified months after infection: reduced exercise capacity.
A national online survey revealed American voters overwhelmingly say they want government and industry to ensure the products they buy are free of harmful chemicals, and they are willing to pay more for it.
The single-celled protozoan Euplotes eurystomus achieves a scurrying walk by coordinate its microscopic uses a simple, mechanical computer instead of a brain like most animals, UCSF researchers found.
Last month new “bivalent” booster vaccines made by Moderna and Pfizer became available that protect against currently circulating Omicron variants as well as earlier strains of the SARS-CoV-2 virus that causes COVID-19. This Q&A features Joel Ernst, MD, a UCSF professor of medicine whose research aims to understand how pathogens evade the immune system.
After a decade of work, scientists at UCSF’s Neuroscape Center have developed a suite of video game interventions that improve key aspects of cognition in aging adults.
Ophthalmologists may be able to safely cut back on having anesthesiologists or nurse anesthetists routinely at bedside during cataract surgery, which accounts for more than two million surgeries per year in the U.S., according to a new study.
A new study shows that fewer Black, Hispanic and Asian patients would qualify for these treatments that may slow Alzheimer’s progression, since cognitive impairment in these groups is more likely to be caused by other forms of dementia that may be unrelated to amyloid plaques.
A newly identified set of molecules alleviated pain in mice while avoiding the sedating affect that limits the use of opiates, according to a new study led by researchers at UC San Francisco.
UCSF has revealed how blood vessel cells develop in the prenatal human brain, paving the way to fully understand the role of these cells in healthy brain development and disease.
The new UCSF Rosenman Institute BUILD™ Heart Health program is designed as an 11-month cycle of fully funded fellowships aimed at training the next generation of health technology entrepreneurs.
Scientists have designed compounds that hit the same key receptor that LSD activates without causing hallucinations. A single dose produced powerful antidepressant and antianxiety effects in mice that lasted up to two weeks.
UCSF researchers Adam Staffaroni, PhD, and Adam Boxer, MD, PhD developed models of clinical and biomarker dynamics to determine the temporal sequence of biomarker and clinical changes in f-FTD before disease progression begins.
UCSF Health is recruiting patients for the only FDA-approved study of the use of single port robotic technology for colorectal surgery in the United States.
Researchers have found significant differences between the gut bacteria profiles of multiple sclerosis (MS) patients and healthy individuals, showing new pathways for potential treatment.
A new therapy pulls forward a mutated version of the KRAS protein to help the immune system recognize and destroy cancer cells.
Children living in neighborhoods with greater hardships, such as substandard housing or high pollution, are more likely to use emergency departments, including for complaints that could be managed by their pediatricians, a new study led by UCSF Benioff Children’s Hospitals found.
A UCSF study found that step counts, a measure of physical activity, were markedly lower early in the COVID-19 pandemic than pre-pandemic and remained lower on average in the two years following the onset of the global pandemic.
UCSF-led research outlines the comprehensive immune landscape and microbiome of pancreatic cysts as they progress from benign cysts to pancreatic cancer. Their findings could reveal the mechanism of neoplastic progression and provide targets for immunotherapy to inhibit progression or treat invasive disease.