Here’s How to Prime Tumors to be Defeated by Cancer Immunotherapy
Scientists discover how to rouse the immune system around "cold" tumors, making them vulnerable to cancer-killing immune therapies with checkpoint inhibitors.
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Estrogen and Progesterone Stimulate the Body to Make Opioids
A new study found that female hormones can suppress pain signals before they reach the brain by making immune cells near the spinal cord produce opioids.
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How Your Immune System Plays Matchmaker to Find and Kill HIV
Ten UCSF graduate students presented their research in accessible, 3-minute talks at the 2025 Grad Slam event. This year’s first-place talk was by Sophia Miliotis on how our immune system uses matchmaking skills to look for signs of viruses in cells that should be destroyed.
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50 Years of Discovery and Influence on the Culture of Science
After a storied scientific career that began with the discovery of how hormones control genes, Keith Yamamoto, PhD, has retired.
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How Your Brain Manages Cholesterol Could Increase Alzheimer’s Risk
Alzheimer’s disease is characterized by a host of recognizable cognitive symptoms, but many non-cognitive symptoms like changes in sleep, anxiety and depression can be early signs of the disease.
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I’m a Long COVID Researcher. And I Have Long COVID
A Q&A w/Alison Cohen, PhD, MPH, who is among the estimated 5% of the population with Long COVID. She talks through the implications of Long COVID, and how she applies her scientific and personal experience to research this debilitating condition.
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1 Gene Variant Is Poised to Cure a Devastating Inherited Disease
COPA syndrome causes lung hemorrhaging starting in childhood. But one in three people with the disease mutation are spared. UCSF scientists have discovered how a separate gene variant protects those relatives – lighting the way to a possible cure.
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Flu Season Worst in 15 years
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Human Chromosomes Evolved at Hyperspeed to Give Us Better Brains
How did humans evolve brains capable of complex language, civilization, and more? Scientists at UC San Francisco recently found that parts of our chromosomes have evolved at breakneck speeds to give us an edge in brain development compared to apes.
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Why Do Women Live Longer Than Men?
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Jumbled Proteins Paint a Bold Target on the Backs of Brain Tumors
UCSF scientists have found that some cancers, like brain cancer, make unique, jumbled proteins that make them stand out. These newly recognized cancer-specific proteins, or antigens, could speed the development of potent immunotherapies that recognize and attack hard-to-treat tumors.
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Worst Flu Season in Years Swamps California: ‘Particularly Long and Difficult’
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Alarming Rise in Rates of Advanced Prostate Cancer in California
Rates of advanced prostate cancer in California rose significantly in the decade since doctors stopped routinely screening all men. A UCSF study reinforces the need for screening that can identify potentially fatal tumors without raising false alarms about ones that pose little threat.
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Could Brain Aging Be Mom’s Fault?
Researchers found that female mice using only maternal X chromosomes showed faster cognitive decline, which could help explain the variation in brain aging between the sexes.
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What’s Behind Preterm Birth? Scientists Just Found a Big Clue
Scientists discover how cells in the uterus keep track of pregnancy to ensure an on-time delivery.
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Can Employees Benefit from a Digital Mindfulness Program?
As little as five minutes of mindfulness meditation a day may help reduce work-related stress, even when done through self-guided smartphone apps.
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How Many Children Use TikTok Against the Rules? Most, Study Finds
High percentages of children under thirteen years old use social media apps that are meant for ages thirteen and over. Experts suggest parents model healthy behaviors to avoid health risks in children.
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Genes That Grow a Healthy Brain Could Fuel Adult Glioblastoma
A new study paints one of the most detailed pictures of human brain development to date, opening the door to new tests and therapies, including for brain disorders such as autism.
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Paxlovid Improved Long COVID Symptoms in Some Patients, Researchers Report
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How HIV Changed Medicine Forever
The quest to defeat HIV/AIDS didn’t just turn a deadly virus into a manageable condition. It transformed science and health care.
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On the Origin of Diseases
Insights from human evolution could change how we understand and treat illness.
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Feel Left Behind by Digital Health Tools? You’re Not Alone
New study finds that, among many factors, speaking Spanish is the most likely to result in lower scores on self-reported ability to navigate digital health tools such as patient portals.
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Oldest Human DNA Reveals Lost Branch of the Human Family Tree
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4 Ways Artificial Intelligence is Poised to Transform Medicine
Artificial intelligence has revolutionized medical imaging. Here are four ways that AI is changing medicine in pictures - and the UCSF minds behind them.
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How This Cancer Drug Could Make Radiation a Slam Dunk Therapy
UCSF scientists developed a way to deliver radiation just to cancerous cells, rather than attacking both cancerous and healthy tissue. The therapy combines a drug to mark the cancer cells for destruction and a radioactive antibody to kill them.
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International Conference Features UCSF Breast Cancer Experts
Breast cancer experts from UCSF Health will present new research and clinical findings at the annual San Antonio Breast Cancer Symposium, the world’s largest and most prestigious breast cancer
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Engineered Immune Cells May Be Able to Tame Inflammation
A new technology uses engineered T cells that act as immune “referees” to soothe overreacting immune responses. They also can mop up inflammatory molecules without lowering the entire body’s immune shields.
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48 UCSF Researchers Are Honored for Their High-Impact Science
Nearly 50 UCSF researchers have been named to Clarivate’s list of most influential scientists for 2024.
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How Optogenetics Can Put the Brakes on Epilepsy Seizures
A technique involving the use of light pulses to prevent seizure-like activity in neurons could one day become a new, non-invasive treatment for epilepsy.
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Engineered Receptors Help the Immune System Home in on Cancer
UCSF researchers develop customizable SNIPR sensors that activate engineered cells only near tumors, promising precise cancer therapies with minimal side effects.
