University of California San Francisco
Give to UCSF<p>Colleagues at the Gladstone and UCSF celebrated the news on Monday that Shinya Yamanaka won the Nobel Prize in Medicine for his discovery that has transformed the field of stem cell research.</p>
<p>Shinya Yamanaka, MD, PhD, a senior investigator at the Gladstone Institutes and a professor of anatomy at UCSF, has won the 2012 Nobel Prize in Physiology or Medicine for his discovery of how to transform ordinary adult skin cells into cells that are capable of developing into any cell in the human body.</p>
<p>Since 1981, when UCSF’s Gail Martin, PhD, co-discovered embryonic stem cells in mice and coined the term embryonic stem cell, UCSF has been a key player in the stem cell field. Today, Shinya Yamanaka became the fifth UCSF scientist to win the Nobel Prize.</p>
Scientists at the UCSF-affiliated Gladstone Institutes have revealed the precise order and timing of hundreds of genetic “switches” required to construct a fully functional heart from embryonic heart cells — providing new clues into the genetic basis for some forms of congenital heart disease.
<p>Biomedical researchers at UCSF have won five of 51 prestigious National Institutes of Health Director’s New Innovator awards for high-risk, high-reward research, each receiving up to $1.5 million over five years.</p>
Scientists at the UCSF-affiliated Gladstone Institutes have discovered that environmental factors critically influence the growth of a type of stem cell — called an iPS cell — that is derived from adult skin cells.
Scientists at the UCSF-affiliated Gladstone Institutes and an international team of researchers have generated a human model of Huntington’s disease — directly from the skin cells of patients with the disease.
Gladstone Institutes Senior Investigator Shinya Yamanaka, MD, PhD, a professor of anatomy at UCSF, has won the Millennium Technology Award Grand Prize, the world’s largest and most prominent technology award.
Scientists at the Gladstone Institutes have for the first time transformed skin cells — with a single genetic factor — into cells that develop on their own into an interconnected, functional network of brain cells.
Chronic pain, by definition, is difficult to manage, but a new study by UCSF scientists shows how a cell therapy might one day be used not only to quell some common types of persistent and difficult-to-treat pain, but also to cure the conditions that give rise to them.
Scientists at the UCSF-affiliated Gladstone Institutes announced a research breakthrough in mice that one day may help doctors restore hearts damaged by heart attacks — by converting scar-forming cardiac cells into beating heart muscle.
Scientists have gained insight into how second-hand tobacco smoke damages the earliest stages of human embryonic development.