University of California San Francisco
Give to UCSFA $147 million grant will expand diversity among Alzheimer’s disease research participants, and involve partners from UCSF, the San Francisco VA Medical Center, and the Northern California Institute for Research and Education.
A small molecule called ISRIB that was identified at UCSF can reverse the neuronal and cognitive effects of concussion in mice weeks after an injury occurred, new research found.
After a decade of work, scientists at UCSF’s Neuroscape Center have developed a suite of video game interventions that improve key aspects of cognition in aging adults.
A new study shows that fewer Black, Hispanic and Asian patients would qualify for these treatments that may slow Alzheimer’s progression, since cognitive impairment in these groups is more likely to be caused by other forms of dementia that may be unrelated to amyloid plaques.
UCSF has revealed how blood vessel cells develop in the prenatal human brain, paving the way to fully understand the role of these cells in healthy brain development and disease.
Scientists have designed compounds that hit the same key receptor that LSD activates without causing hallucinations. A single dose produced powerful antidepressant and antianxiety effects in mice that lasted up to two weeks.
Researchers have found significant differences between the gut bacteria profiles of multiple sclerosis (MS) patients and healthy individuals, showing new pathways for potential treatment.
The study, funded by the National Institute on Aging, recruited people who were 50 and older and homeless, and followed them for a median of 4.5 years. By interviewing people every six months about their health and housing status, researchers were able to examine how things like regaining housing, using drugs, and having various chronic conditions, such as diabetes, affected their risk of dying.
The discovery of how to shift damaged brain cells from a diseased state into a healthy one poses a potential new path to treating Alzheimer’s and other forms of dementia, according to a new study from UCSF researchers.
Blood tests taken within 24 hours of a traumatic brain injury (TBI) flag which patients are likely to die and which patients are likely to survive with severe disability, according to a study headed by UCSF, the University of Pennsylvania and the University of Michigan.
Severe restrictions and bans on abortion access may have life-changing and even life-threatening consequences in as many as 28 states for women of childbearing age with conditions like migraine, multiple sclerosis (MS) and epilepsy.
A new study shows that when residents in Black communities have a stroke, they are at greater risk of receiving care at a less-resourced hospital, where their chances of recovery are slimmer.
In a new study of Alzheimer’s disease, UCSF reserachers have discovered that a relatively unstudied form of the tau protein associated with neurodegeneration may be a means for better diagnosis and treatment of the disease.
In a new study of long COVID, UCSF researchers identified biomarkers present at elevated levels that may persist for many months in the blood of study participants who had long COVID with neuropsychiatric symptoms.
In a study, UCSF neurologist William Seeley, MD, and colleagues identified two key moments in the natural history of Alzheimer’s, pointing to a window of opportunity for treatment with amyloid-lowering drugs.
Brain tumor patients survived longer when treated aggressively with surgery, radiation and chemotherapy. Now, a UCSF study underscores the critical role of genomic profiling in diagnosing and grading brain tumors.
This study is believed to be the first to report the rate of dementia in Native Americans using a nationwide sample, the researchers stated in their paper.
Scientists at UC San Francisco and Imperial College London found that psilocybin fosters greater connections between different regions of the brain in depressed people, freeing them up from long-held patterns of rumination and excessive self-focus.
The findings contradict the common notion that Alzheimer’s patients sleep during the day to make up for a bad night of sleep and point toward potential therapies to help these patients feel more awake.
Daytime napping among older people is a normal part of aging – but it may also foreshadow Alzheimer’s disease and other dementias.
Not everyone needs 8 hours of sleep, say UCSF researchers. Some lucky people are “elite sleepers,” packing sleep’s benefits into 4 to 6 hours a night. Their genes may hold clues to how efficient sleep can fend off dementia.