How Can We Be Sure the New COVID-19 Vaccines Are Safe?
We asked several UCSF experts for a personal take on what will convince them that a vaccine is safe.
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Astonishing Animals That Illuminate Human Health
Giant lizards with superpowered hearts. Hairless rodents that don’t seem to age. Songbirds that babble like human babies. These and other scurrying, soaring, and slithering wonders are teaching scientists how our own bodies work – and how to fix them.
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Drug Reverses Age-Related Mental Decline Within Days
In the new study, UCSF researchers showed rapid restoration of youthful cognitive abilities in aged mice, accompanied by a rejuvenation of brain and immune cells that could help explain improvements in brain function.
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This Professor Sees Brain Disease through a Unique Lens
Every fall, Matt Jacobson relives his Parkinson’s diagnosis so future pharmacists perceive the patient behind the prescription.
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Big Data Powers Design of ‘Smart’ Cell Therapies for Cancer
Finding medicines that can kill cancer cells while leaving normal tissue unscathed is a Holy Grail of oncology research.
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Scientists Look to Neutralize the SARS-CoV-2 Spike for Potential Therapies
SARS-CoV-2 uses its distinctive spike to latch onto a receptor called ACE2 on the surface of a human cell. Once there it prompts the human cell to ferry the virus inside. Then, the virus co-opts human enzymes to make copies of itself and spread to other cells.
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Engineered Developmental Signals Could Illuminate Regenerative Medicine
For a tiny embryo to develop into an adult organism, its cells must develop in precise patterns and interact with their neighbors in carefully orchestrated ways. To create complex tissues and organs –
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International Team of Scientists Identifies Common Vulnerabilities Across Coronaviruses
An international team of researchers studied the three lethal coronaviruses SARS-CoV-2, SARS-CoV-1 and MERS-CoV in order to identify commonly hijacked cellular pathways and detect promising targets for broad coronavirus inhibition.
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UCSF Researchers Test New COVID-19 Drug
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Customizable Synthetic Antibiotic Outmaneuvers Resistant Bacteria
Researchers at UCSF are tackling antibiotic resistance using a different approach: redesigning existing antibiotic molecules to evade a bacterium’s resistance mechanisms
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Archive: In Tiny Llama Antibodies, Researchers See Hope for a Coronavirus Treatment
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Archive: ‘AeroNabs’ Promise Powerful, Inhalable Protection Against COVID-19
UCSF scientists have devised a novel approach to halting the spread of SARS-CoV-2, the virus that causes the disease.
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Archive: How COVID Sends Some Bodies to War With Themselves
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Archive: Some ‘Inert’ Drug Ingredients May Be Biologically Active
Some supposedly inert ingredients in common drugs — such as dyes and preservatives — may potentially be biologically active and could lead to unanticipated side effects, according to a preliminary new study by researchers from the UCSF and the Novartis Institutes for BioMedical Research.
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Archive: ‘Wasabi Receptor’ Reveals Its Eye-Watering Secrets
UCSF researchers have now determined how the TRPA1 molecule manages to sense such a diverse variety of dangerous chemicals – and do so with enough sensitivity to let you flee before suffering too much tissue damage.
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Seeking Immunity Against COVID-19
Joel Ernst, MD, addresses key questions about how vaccine development works and why vaccines are especially important in the case of COVID-19.
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COVID-19 Frontliners: the Stem Cell Biologist
Why are more men than women dying of COVID-19? Scientist Faranak Fattahi, PhD, has found a clue.
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Archive: How Exercise May Bolster the Brain
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Archive: Building Blocks for COVID-19 Antiviral Drugs Identified in Rapid Study
Scientists have identified key chemical building blocks for an eventual antiviral drug against SARS-CoV-2, the virus that causes COVID-19.
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Archive: Newly Diagnosed COVID-19 Patients Needed for Antibiotic Clinical Trial
The nationwide clinical trial will assess whether the common antibiotic azithromycin can reduce hospitalization stays and death caused by the SARS-CoV-2 virus.
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Archive: Recombinant Antibody Network Partners with Bristol Myers Squibb to Develop Novel Therapies
Under a new agreement, Celgene will further invest in the RAN’s state-of-the-art antibody engineering program to expand target discovery from oncology and immunology to include neurology.
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Archive: How a Key Protein Juggles Multiple Demands to Keep Neurons Firing
UCSF researchers have become to the first to solve the structure of a hard-working protein that helps reload neurons for repeated firing.
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Archive: Chasing a Killer: Inside a UCSF Lab's Urgent, Unprecedented Effort to Decode and Destroy the Deadly Coronavirus
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Archive: Old Drugs May Find a New Purpose: Fighting the Coronavirus
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Archive: Nature Publication Presents New ‘Blueprint’ Revealing How SARS-CoV-2 Virus Hijacks Human Cells
An international team of more than 120 scientists has detailed the impact of 75 over-the-counter prescription and development-stage drug compounds on SARS-CoV-2, the virus that causes COVID-19.
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Archive: The Promise and Uncertainties of Antibody Testing for Coronavirus
As people around the world try to envision recovery from the COVID-19 pandemic, much attention has been paid to antibody testing as a way to identify people who have developed immunity to the virus. UCSF experts explain how antibody testing works, who it can be most useful for and why we should be cautious.
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Archive: Clinical Trial Testing If Common Anti-Inflammatory Drug Reduces Hospitalization, Death Caused by Coronavirus
UCSF is recruiting newly diagnosed COVID-19 patients for a large global clinical trial testing whether the common anti-inflammatory drug colchicine can reduce hospitalization and death caused by the illness.
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Archive: Unveiling How Coronavirus Hijacks Our Cells to Help Rush New Drugs to Patients
Though many hopes are hanging on the development of a vaccine or drug that targets the novel coronavirus directly, a UCSF-led team is taking an unconventional approach: target the host – in other words, you.
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Archive: Scientists Identify 69 Drugs to Test Against the Coronavirus
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Archive: Hundreds of Scientists Scramble to Find a Coronavirus Treatment