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Bacteria that normally live in and upon us have genetic blueprints that enable them to make thousands of molecules that act like drugs, and some of these molecules might serve as the basis for new human therapeutics, according to UCSF researchers.
Peter Walter has won the 2014 Lasker Award, popularly known as the "American Nobels." It’s the second major accolade this year alone for the Germany native, whose career didn't always point toward being a research scientist.
New research partly led by UCSF-affiliated scientists suggests that one in 10 cancer patients would be more accurately diagnosed if their tumors were defined by cellular and molecular criteria rather than by the tissues in which they originated.
A new study is the first to show that while the impact of life’s stressors accumulate over time and accelerate cellular aging, these negative effects may be reduced by maintaining a healthy diet, exercising and sleeping well.
In a new study led by UCSF scientists, a chemical compound designed to precisely target part of a crucial cellular quality-control network provided significant protection, in rats and mice, against degenerative forms of blindness and diabetes.
A team of researchers studying a flowering plant has zeroed in on the way cells manage external signals to adapt to prevailing conditions, a capability that is essential for cells to survive in a fluctuating environment.
The calorie-burning triggered by cold temperatures can be achieved biochemically – without the chill – raising hopes for a weight-loss strategy focused on the immune system rather than the brain, according to a new UCSF study.
There are 100 trillion bacterial cells living in and on our bodies. In the spring issue of UCSF Magazine, find out how these bacteria could be the key to treating and preventing a number of conditions from asthma to obesity.
UCSF's Peter Walter has received Asia’s highest scientific honor, the 2014 Shaw Prize in Life Science and Medicine, for his groundbreaking discovery of a cellular system that makes “life and death decisions” for the cell.
The Food and Drug Administration has selected UCSF as the site of a new regulatory science center on the West Coast. The center aims to spur innovative approaches in drug development that will support the FDA’s ability to evaluate and approve safe and effective new medications.
The stiffening of breast tissue in breast-cancer development points to a new way to distinguish a type of breast cancer with a poor prognosis from a related, but often less deadly type, UCSF researchers have found in a new study.
Research led by scientists at the UCSF-affiliated Gladstone Institutes has identified the precise chain of molecular events in the human body that drives the death of most of the immune system’s CD4 T cells as an HIV infection leads to AIDS. Further, they have identified an existing anti-inflammatory drug that in laboratory tests blocks the death of these cells.