Off-Switch for CRISPR-Cas9 Gene Editing System Discovered
UCSF researchers have discovered a way to switch off the widely used CRISPR-Cas9 gene-editing system using newly identified anti-CRISPR proteins that are produced by bacterial viruses.
University of California San Francisco
Give to UCSFUCSF researchers have discovered a way to switch off the widely used CRISPR-Cas9 gene-editing system using newly identified anti-CRISPR proteins that are produced by bacterial viruses.
A newly identified bacterial protein that is shown to jump-start infection may be the culprit in a foodborne disease that strikes pregnant women in disproportionately high numbers, leading to miscarriage and pre-term birth.
In findings that show the effectiveness of a new strategy for treating multiple sclerosis, researchers are reporting positive results from three large, international, multicenter Phase III clinical trials of the investigational drug ocrelizumab in both relapsing multiple sclerosis and primary progressive multiple sclerosis.
UCSF scientists have discovered an unexpected mechanism the brain uses to seamlessly compensate when speech sounds are obscured by noise.
To give you a bit of scientific motivation, UCSF gathered some of the latest research behind the most popular health-related New Year’s resolutions that attest to why it really is good for your body to see them through.
UC San Francisco researchers have visualized the earliest stages of pregnancy in unprecedented detail in laboratory animals and human tissue using new laboratory imaging techniques.
Stories about sensory processing disorder, videos about “zombie” cancer cells, and news about the effects of caffeine and alcohol on the heart were among the topics that most engaged our readers in 2016.
Nearly half of the patients in a safety net health system who had an abnormal stool-based screening test for colorectal cancer failed to receive the recommended colonoscopy within a year.
A national survey has found an association between pubic hair grooming and sexually transmitted infections.
UCSF researchers have developed a new variety of targeting system for chemotherapy drugs based on the unusually high free iron content of many cancer cells.
Beta blockers are effective in reducing the risk of death in older nursing home residents after a heart attack, but may impair their ability to perform daily functions independently.
UC San Francisco and the Veterans Affairs Medical Center in San Francisco has found that change in telomere length over time is important.
California adolescents perceive smoking cigarettes to be riskier – and less socially acceptable – than they did a dozen years ago.
UCSF is addressing racial disparities in clinical research, helping to advance precision medicine by providing tailored medical treatment to vulnerable populations.
A shared biological mechanism may drive the progression of both Alzheimer’s disease and chronic traumatic encephalopathy, a neurodegenerative condition associated with repeated concussions and brain trauma.
The UCSF School of Dentistry and UC Berkeley’s School of Public Health have announced the launch of a joint program for dentists interested in dental public health.
UCSF-led research team identified the rare genetic mutation responsible for a unique case of severe combined immunodeficiency, a deadly immune system disorder also known as “boy in the bubble” disease.
UCSF researchers identified fetal brain tissue cells that are targeted by the Zika virus and determined that azithromycin can prevent the virus from infecting these cells.
UCSF researchers have received $1.2 million for their work to make imaging machines smarter, so they can detect neurological emergencies and triage patients for immediate treatment.
UCSF researchers found a way to pause the development of early mouse embryos for up to a month in the lab, a finding with implications for assisted reproduction, regenerative medicine, aging and cancer.
White blood cells called neutrophils race after bacteria at speeds up to a thousand times that of most human cells by moving in a special way. Lillian Fritz-Laylin and Megan Riel-Mehan want to know how that works.
Strict blood pressure control is associated with a reduced chance of long-term kidney damage in patients with type 1 diabetes, according to a new long-term study led by UC San Francisco researchers.
UCSF’s Center for Digital Health Innovation and GE Healthcare today announced a partnership to develop a library of deep learning algorithms.
The U.S. Food and Drug Administration has awarded the UCSF-Stanford Center of Excellence in Regulatory Science and Innovation (UCSF-Stanford CERSI) a five-year grant with up to $25 million in funding.
Next-generation sequencing for patients at UCSF Medical Center is prompting changes in brain tumor diagnoses for some children and a retooling of treatment plans in many cases.
Smartphone use directly correlates with sleep, with greater use demonstrating a significant association with shorter sleep duration and worse sleep efficiency, according to researchers at UCSF.
People who sleep five or fewer hours a night are likely to also drink significantly more sugary caffeinated drinks.
Researchers at UCSF are pioneering a new technique, known as quantitative magnetic resonance imaging, or qMRI, that can reveal the earliest signs of cartilage damage, a precursor to osteoarthritis.
Low income and Latina pregnant women who seek care at ZSFG have widespread exposure to environmental pollutants, many of which show up in higher levels in newborns.
Graduate student Lauren Rodda captured a microscopic mage of a mouse gut, which highlights her work to understand the germinal center, where immune cells compete to be the best at recognizing an invading pathogen.