University of California San Francisco
Give to UCSFUnder a new agreement, Celgene will further invest in the RAN’s state-of-the-art antibody engineering program to expand target discovery from oncology and immunology to include neurology.
The finding could offer additional insights into other immune conditions, including a type of childhood leukemia and the severe inflammation response in some children with COVID-19.
Older men who have a weak or irregular circadian rhythm guiding their daily cycles of rest and activity are more likely to later develop Parkinson’s disease, according to a new study by scientists at the UCSF Weill Institute for Neurosciences who analyzed 11 years of data for nearly 3,000 independently living older men.
Depending on a cancer’s tissue of origin, tumors cause widespread and variable disruption of the immune system throughout the body, not just at the primary tumor site.
In a new study in mice, UCSF researchers investigated what enables neurons in the visual system to respond to context when a stimulus is not available. They found that feedback from higher-order visual centers in the brain has much more influence over our fundamental visual processing than scientists had ever realized.
Cancer specialists from UCSF will present new research findings at the annual scientific program of the American Society of Clinical Oncology, the world’s largest clinical cancer research meeting.
A new UCSF study in mice has pinpointed a specific pattern of brain waves that underlies the ability to let go of old, irrelevant learned associations to make way for new updates.
UCSF researchers have become to the first to solve the structure of a hard-working protein that helps reload neurons for repeated firing.
UCSF researchers have identified a powerful self-corrective mechanism within synapses that is activated by neurodegeneration and acts to slow down disease progression in animal models of ALS.
Cancer and autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis, might not seem to have much in common, but some researchers now are pinning hopes on the same immune system cell –
A project launched by UC San Francisco and UC Berkeley scientists evaluated some of the more than 120 available antibody test kits.
UCSF researchers now have reported a new method to design and test cell therapies, one they expect will speed the development of new life-saving treatments not only for cancer, but for other diseases, too.
A simple urine test can diagnose and predict acute rejection in kidney transplants, leading to an opportunity for earlier detection and treatment, according to a new study by researchers at UCSF.
UC San Francisco researchers have finally identified the cellular circuit responsible for conveying stress signals from inside mitochondria to the integrated stress response, a discovery that may have important implications for treating the many debilitating diseases associated with mitochondrial stress.
A new UCSF study of patients with Parkinson’s disease has revealed a pathway that transmits signals very rapidly between two parts of the human brain to govern the complex act of halting a motion once it’s been initiated.
UCSF scientists have made a significant advance toward understanding a rare genetic condition, almost exclusively affecting females, that results in a broad spectrum of neurodevelopmental deficits.
A simple blood test may soon be able to diagnose patients with two common forms of dementia – Alzheimer’s disease and frontotemporal dementia – and tell the two apart.
A blood test that may eventually be done in a doctor’s office can swiftly reveal if a patient with memory issues has Alzheimer’s disease or mild cognitive impairment and can also distinguish both conditions from frontotemporal dementia.
For a conditioned response to become long-lasting requires brain cells to increase amounts of an insulating material called myelin, which may serve to reinforce and stabilize newly formed neural connections.
Survival may more than double for adults with glioblastoma, if neurosurgeons remove the surrounding tissue as aggressively as they remove the cancerous core of the tumor.
Understanding the biological differences that drive distinct symptoms of Alzheimer’s disease could lead to more personalized patient care and potentially therapies targeted to patients’ individual needs.