Your Pain Meds’ Side Effects May Be Masquerading as Heart Failure
Matthew Growdon's study finds "prescription cascades" where drug side effects lead to unnecessary second prescriptions, causing further harm and costly hospitalizations.
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Why a Foreign Language Sounds Like a Blur to Non-Native Ears
Scientists have thought that when we hear language, the brain processes it the same way, whether it's familiar or foreign. A new study reveals that exposure to a language changes how certain clusters of neurons respond to the familiar sounds. From those changes, we develop the understanding of syllables, words, and syntax.
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This New Tech Helps Parkinson’s Patients Who Have Trouble Walking
UCSF researchers used AI to personalize Deep Brain Stimulation (DBS) for Parkinson's gait problems, leading to meaningful, customized improvements in walking and mobility—a major breakthrough for patients.
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Why Is It So Hard to Adjust When Clocks ‘Fall Back’?
Neurologist Dr. Ptacek explains how "falling back" disrupts the 24-hour circadian clock, affecting mood and performance, with mitigation tips.
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How to Turn Genes On or Off to Protect Brain Cells From Dementia
Martin Kampmann’s work, supported by the National Institutes of Health (NIH), maps cellular “decision points” that determine whether brain cells survive or die, laying the groundwork for treatments that intervene before irreversible brain damage occurs from dementia.
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How Multiple Sclerosis Harms a Brain Long Before Symptoms Appear
Image In the human brain, neurofilament light chain (NfL, shown in brown) is seen in brain cells and the neural wires that connect them. UCSF
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Could This Birth Control Shot Increase Your Risk for Brain Tumor?
UCSF radiation oncologist David Raleigh, MD, PhD, studies the link between brain tumors and injectable birth control.
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Signs of Dyslexia and Reading Troubles Can Be Spotted in Kindergarten — or Even Preschool
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Scientists Used AI to Map Uncharted Areas of the Mouse Brain
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Could This Novel Therapy Calm Anxiety for Millions of Americans?
Generalized anxiety disorder affects 1 in 20 U.S. adults. Those with serious symptoms may isolate themselves to the point that they rarely leave their home.
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UCSF Study on CTE Seeks Living Athletes’ Data to Help Diagnose the Degenerative Disease
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If Anti-Seizure Meds Don’t Work for Epilepsy, Can Surgery Help?
Vikram Rao, director of the UCSF Epilepsy Center, discusses why a third of seizure patients don’t respond to medication and the promising new surgical and technological treatments available.
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These Cells Have Hidden Powers That Could Heal Brain Injuries
UCSF scientists discovered that an overlooked cell type in the brain plays a central role in healing traumatic brain injury. Understanding how it does this will lead to treatments for injuries that currently have only minimal interventions.
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Scientists Look to Commercial Dyes to Help them Diagnose Dementia
A study screened dyes found in textiles and in the laser industry that can be used in imaging for preclinical studies to diagnose and differentiate between neurodegenerative diseases. Currently, dyes used in mouse studies cannot distinguish between different types of dementia.
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Bruce Willis’ Personality Changes Key to Dementia Diagnosis: UCSF Expert
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From Chronic Pain to Parkinson’s, 4 Ways DBS is Changing Care
UCSF looks back on four ways it pioneered deep brain stimulation with the help of federal funding, helping patients with Parkinson’s Disease, chronic pain, depression, and more.
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This Protein Slows the Aging Brain, and We Know How to Counter It
Scientists discover a protein that gets concentrated in the brain during aging, leading brain connections to wither and cognitive decline to accelerate - and a way to counter its effects.
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Treating Chronic Pain is Hard. An Experimental Approach Shows Promise.
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Two UCSF Researchers Are Named Pew Latin American Fellows
Two new Pew Latin American fellows, Beatriz De Moraes, PhD, and Lilian Gomes de Oliveira, PhD, will each receive a $30,000 annual stipend for two years to support their work at the crossroads of immunology and neuroscience.
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Composer Reimagines His Harvey Milk Opera While Rebuilding Life After Traumatic Injury
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Meet the Little Brain Region that Helps You Say What’s on Your Mind
Researchers discovered that a different part of the brain handles stringing sounds and words together into coherent sentences. The information could help people who have had strokes and lost the ability to create sentences.
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These Immune Cells Eat Molecular Trash to Keep Alzheimer’s at Bay
Microglia, a type of brain immune cell, can gobble up amyloid beta protein, which clumps together into toxic aggregates during Alzheimer's disease.
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Do These Two Cancer Drugs Have What It Takes to Beat Alzheimer’s?
Scientists at UCSF and Gladstone Institutes have identified cancer drugs that promise to reverse the changes that occur in the brain during Alzheimer’s, potentially slowing or even reversing its symptoms.
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Tailored Deep Brain Stimulation Improves Walking in Parkinson’s
For patients with Parkinson's disease, changes in their ability to walk can be dramatic. “Parkinson’s gait,” as it is often called, can include changes in step length and asymmetry between legs. This
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A CRISPR Approach to Neurodegenerative Diseases
The Byers Award recognizes outstanding research by faculty members in the middle of their careers. Martin Kampman’s honorary 2025 lecture is titled “A CRISPR approach to neurodegenerative diseases.”
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Visual Migraine Symptoms Linked to Tiny Brain Lesions
Visual auras, like those that occur in migraines, may be signs of small injuries to the brain’s visual cortex, according to a clinical trial at UC San Francisco that tracked the appearance of these
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Why Do Some Brain Regions Resist Alzheimer’s?
It’s been recognized for some time that Alzheimer’s disease affects brain regions differently and that tau — a protein known to misbehave — plays an important role in the disease. Normally, tau helps
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Can Music Benefit Our Brains?
An expert in cognitive neuroscience shares the ways that music may help flex our neurons, plus her top tips for a music-filled life.
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Why Is Discovery Research So Important?
Neuroscientist Grae Davis, PhD, unpacks why public understanding of science matters.
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Can We Train Our Brain to Unlearn Chronic Pain?
Scientists are working to rewire the brain’s pain pathways and unlock lasting relief.
