Small-Molecule Drug Reverses Neural Effects of Concussion
A small molecule called ISRIB that was identified at UCSF can reverse the neuronal and cognitive effects of concussion in mice weeks after an injury occurred, new research found.
University of California San Francisco
Give to UCSFA small molecule called ISRIB that was identified at UCSF can reverse the neuronal and cognitive effects of concussion in mice weeks after an injury occurred, new research found.
After a decade of work, scientists at UCSF’s Neuroscape Center have developed a suite of video game interventions that improve key aspects of cognition in aging adults.
A new study shows that fewer Black, Hispanic and Asian patients would qualify for these treatments that may slow Alzheimer’s progression, since cognitive impairment in these groups is more likely to be caused by other forms of dementia that may be unrelated to amyloid plaques.
A newly identified set of molecules alleviated pain in mice while avoiding the sedating affect that limits the use of opiates, according to a new study led by researchers at UC San Francisco.
UCSF has revealed how blood vessel cells develop in the prenatal human brain, paving the way to fully understand the role of these cells in healthy brain development and disease.
Scientists have designed compounds that hit the same key receptor that LSD activates without causing hallucinations. A single dose produced powerful antidepressant and antianxiety effects in mice that lasted up to two weeks.
A mortality prediction model for older adults with dementia may help physicians determine which treatments to provide while facilitating decision-making for patients and their families.
Researchers have found significant differences between the gut bacteria profiles of multiple sclerosis (MS) patients and healthy individuals, showing new pathways for potential treatment.
The study, funded by the National Institute on Aging, recruited people who were 50 and older and homeless, and followed them for a median of 4.5 years. By interviewing people every six months about their health and housing status, researchers were able to examine how things like regaining housing, using drugs, and having various chronic conditions, such as diabetes, affected their risk of dying.
When our eyes move during REM sleep, we’re gazing at things in the dream world our brains have created, according to a new study by UCSF researchers. The findings shed light not only into how we dream, but also into how our imaginations work.
The discovery of how to shift damaged brain cells from a diseased state into a healthy one poses a potential new path to treating Alzheimer’s and other forms of dementia, according to a new study from UCSF researchers.
Blood tests taken within 24 hours of a traumatic brain injury (TBI) flag which patients are likely to die and which patients are likely to survive with severe disability, according to a study headed by UCSF, the University of Pennsylvania and the University of Michigan.
UCSF Medical Center has been ranked among the country’s finest hospitals in adult care by U.S. News & World Report’s prestigious Best Hospitals survey.
Severe restrictions and bans on abortion access may have life-changing and even life-threatening consequences in as many as 28 states for women of childbearing age with conditions like migraine, multiple sclerosis (MS) and epilepsy.
UCSF is welcoming its first patients to the Nancy Friend Pritzker Psychiatry Building, a one-of-a-kind treatment center that aims to redefine mental health services and make a bold statement against stigma.
A new study shows that when residents in Black communities have a stroke, they are at greater risk of receiving care at a less-resourced hospital, where their chances of recovery are slimmer.
When Cheryl Broyles was diagnosed with glioblastoma, her goal was to outlive the disease’s 15-month prognosis. That was 22 years ago. Broyles’ survival has been the result of luck, tumor location, and cutting-edge treatment and diagnostics.
UCSF Benioff Children’s Hospitals have been recognized among the nation’s best pediatric medical centers in all 10 specialties assessed in U.S. News & World Report's Best Children’s Hospitals 2022-23, reflecting the caliber of specialty care the hospitals provide.
Glimpse the technologies that will catapult neurosurgery to the next level of precision.
How David Julius and Ardem Patapoutian found the molecules in our bodies that sense heat, cold, touch, and pain – and transformed sensory neuroscience.
In a new study of Alzheimer’s disease, UCSF reserachers have discovered that a relatively unstudied form of the tau protein associated with neurodegeneration may be a means for better diagnosis and treatment of the disease.