To Let Neurons Talk, Immune Cells Clear Paths Through Brain’s ‘Scaffolding’
A new study by UCSF researchers identified a surprising way that the brain’s immune cells help to form new memories.
University of California San Francisco
Give to UCSFA new study by UCSF researchers identified a surprising way that the brain’s immune cells help to form new memories.
Under a new agreement, Celgene will further invest in the RAN’s state-of-the-art antibody engineering program to expand target discovery from oncology and immunology to include neurology.
Older men who have a weak or irregular circadian rhythm guiding their daily cycles of rest and activity are more likely to later develop Parkinson’s disease, according to a new study by scientists at the UCSF Weill Institute for Neurosciences who analyzed 11 years of data for nearly 3,000 independently living older men.
In a new study in mice, UCSF researchers investigated what enables neurons in the visual system to respond to context when a stimulus is not available. They found that feedback from higher-order visual centers in the brain has much more influence over our fundamental visual processing than scientists had ever realized.
A new UCSF study in mice has pinpointed a specific pattern of brain waves that underlies the ability to let go of old, irrelevant learned associations to make way for new updates.
UCSF researchers have become to the first to solve the structure of a hard-working protein that helps reload neurons for repeated firing.
UCSF researchers have identified a powerful self-corrective mechanism within synapses that is activated by neurodegeneration and acts to slow down disease progression in animal models of ALS.
The two from UCSF are among 120 new members elected to the Academy in 2020.
UC San Francisco researchers have finally identified the cellular circuit responsible for conveying stress signals from inside mitochondria to the integrated stress response, a discovery that may have important implications for treating the many debilitating diseases associated with mitochondrial stress.
A new UCSF study of patients with Parkinson’s disease has revealed a pathway that transmits signals very rapidly between two parts of the human brain to govern the complex act of halting a motion once it’s been initiated.
UCSF scientists have made a significant advance toward understanding a rare genetic condition, almost exclusively affecting females, that results in a broad spectrum of neurodevelopmental deficits.
A simple blood test may soon be able to diagnose patients with two common forms of dementia – Alzheimer’s disease and frontotemporal dementia – and tell the two apart.
A blood test that may eventually be done in a doctor’s office can swiftly reveal if a patient with memory issues has Alzheimer’s disease or mild cognitive impairment and can also distinguish both conditions from frontotemporal dementia.
For a conditioned response to become long-lasting requires brain cells to increase amounts of an insulating material called myelin, which may serve to reinforce and stabilize newly formed neural connections.
Survival may more than double for adults with glioblastoma, if neurosurgeons remove the surrounding tissue as aggressively as they remove the cancerous core of the tumor.
Leaders in dementia from Latin America joined community members from the Global Brain Health Institute, Alzheimer’s Association, the Tau Consortium, the National Institute of Health (NIH) and more at UCSF Mission Bay for the US-Latin American Networking on Dementia Symposium. Cohosted by GBHI and the UCSF Memory and Aging Center.
In a study of rats navigating a simple maze, neuroscientists at UCSF have discovered how the brain may generate such imagined future scenarios. The work provides a new grounding for understanding not only how the brain makes decisions but also how imagination works more broadly, the researchers say.
Widely used organoid models fail to replicate even basic features of brain development and organization, much less the complex circuitry needed to model complex brain diseases or normal cognition.
UCSF postdoctoral researcher for the first time succeeded in keeping a diverse array of glioblastomas alive in the lab using brain organoids
Scientists have documented the influence of information overload on attention, perception, memory, decision-making, and emotional regulation. But the same technologies contributing to the cognition crisis could help solve it, argues neuroscientist Adam Gazzaley.
From international awards for high-caliber research to groundswell movements for social change, this past year was an eventful one for the UCSF community.
Browse the stories that most engaged our readers in 2019.