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Senescent fibroblasts are aging cells in connective tissue that no longer divide and protect against tumor development. Yet, these same cells can promote cancer growth in a laboratory setting.Until
To address the specific challenges faced by older adults with inflammatory bowel disease (IBD), UCSF Health created the UCSF IBD Longevity Clinic to provide comprehensive and specialized care for patients aged 65 and older with this chronic condition.
Doctors have reduced opioid prescribing since the opioid epidemic’s peak, but a UCSF study found that this trend affects nursing home residents with chronic pain. An analysis of 3M residents saw declines in opioid use, with racial disparities in prescribing.
New research shows that the surrounding cells and tissues of the ovary play a crucial role in how eggs mature and how quickly fertility wanes.
Ahead of the 2025 Nobel Prize announcements, we take a look back at UCSF's Nobel laureates, their discoveries, and the UCSF research building on their work today.
A study screened dyes found in textiles and in the laser industry that can be used in imaging for preclinical studies to diagnose and differentiate between neurodegenerative diseases. Currently, dyes used in mouse studies cannot distinguish between different types of dementia.
Scientists discover a protein that gets concentrated in the brain during aging, leading brain connections to wither and cognitive decline to accelerate - and a way to counter its effects.
Award-winning UCSF mentors Judith Hellman and Tor Neilands share their keys to success: deep commitment, individualized support, empathy, and responsiveness. They emphasize listening, tailoring guidance, and utilizing UCSF’s robust mentoring resources to foster future generations.
UCSF Medical Center has been ranked among the country’s best hospitals in adult care in U.S. News & World Report’s prestigious Best Hospitals survey.
It’s been recognized for some time that Alzheimer’s disease affects brain regions differently and that tau — a protein known to misbehave — plays an important role in the disease. Normally, tau helps
A critical step in meeting the needs of the growing aging population is early recognition of cognitive decline. In California, women who live to be 65 or older have a one in four chance of developing
Many experts believe that social isolation is a risk factor for Alzheimer’s disease, but a new study found that the disease may make them more sociable rather than less — at least in the early stages.
An expert in cognitive neuroscience shares the ways that music may help flex our neurons, plus her top tips for a music-filled life.
In one of the largest studies of its kind, researchers identified the U.S. regions where dementia occurs most often.
UCSF researchers have found clues about how frontotemporal dementia develops that could lead to new diagnostics and get more patients into clinical trials.
A study followed the sleep patterns of older female participants to see if specific patterns of change were associated with a higher risk of dementia. The participants, whose average age was 83, were monitored by wrist devices that track movement and time spent asleep.
To help patients recover more quickly, hospitals may provide physical and occupational therapy – especially for older adults to help them preserve or regain function. How much therapy is best, though, isn’t clear.
Why do women's brains fare better in aging than men's? A study found that the second, 'silent' X chromosome turns on in the brain of old female mice and improves learning and memory – opening new paths to slow the decline in men and women.
A study found that B12 requirements may be too low for some people, putting them at risk for cognitive decline.
A new EPA ban on TCE, a common industrial cleaning agent and contaminant, begins this year. UCSF’s Samuel Goldman, who led groundbreaking research to link TCE to Parkinson’s Disease, talks about the health risks.
Researchers found that female mice using only maternal X chromosomes showed faster cognitive decline, which could help explain the variation in brain aging between the sexes.
A new study found that menopause can speed up the progression of multiple sclerosis (MS), affecting mobility and cognitive ability.
