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Liver Cells Switch Identities to Grow New Tissue

By studying a rare liver disease called Alagille syndrome, scientists from UC San Francisco and Cincinnati Children’s Hospital Medical Center have discovered the mechanism behind an unusual form of tissue regeneration that may someday reduce the need for expensive and difficult-to-obtain organ transplants.

Time for Joy: Stopping a Rare Disease In a New Genomic Era

Severe combined immunodeficiency (SCID) if undetected can be lethal by the time a child turns 1 year old. UCSF researchers created a screening test for SCID, which impacts Navajo families at a far higher rate than the rest of the population.

Photo of Joy Littlesunday hamming it up with her parents, Jarvison and Christina.

Surprising New Role for Lungs: Making Blood

Using video microscopy in the living mouse lung, UC San Francisco scientists have revealed that the lungs play a previously unrecognized role in blood production.

Researchers Use CRISPR to Accelerate Search for HIV Cure

Researchers at UCSF and the academically affiliated Gladstone Institutes have used a newly developed gene-editing system to find gene mutations that make human immune cells resistant to HIV infection.