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Loss of an enzyme that modifies gene activity to promote brain regeneration may be partly responsible for age-related cognitive decline, according to new research in laboratory mice by UCSF.
Many researchers have long assumed that most stem cells in the body can produce new cells indefinitely, but new research at UCSF shows that this is not the case in the brain.
UCSF bioengineers have shown that many of the complex folded shapes that form mammalian body plans and internal tissue structures can be recreated with very simple instructions.
Severe combined immunodeficiency (SCID) if undetected can be lethal by the time a child turns 1 year old. UCSF researchers created a screening test for SCID, which impacts Navajo families at a far higher rate than the rest of the population.
Whether you are seeing them for the first time or coming back for another look, check out the most popular scientific stories from UC San Francisco from the past year.
UCSF have taken the first step toward a comprehensive atlas of gene expression in cells across the developing human brain.
Researchers at UCSF have developed a new genetic model of autism, using neurons created in the lab from patients’ own skin cells.
Encellin obtained exclusive rights from UCSF for a proprietary cell encapsulation technology aimed at improving physicians’ ability to perform cell transplants without the need for immunosuppressive drugs.
Deepak Srivastava has been appointed president of Gladstone Institutes. His term will begin on Jan. 1, 2018.
UCSF Benioff Children’s Hospitals will pioneer stem cell transplants for a uniquely challenging patient population: second-trimester fetuses stricken with a potentially fatal disease.
A virus hiding quietly in the gut may trigger the onset of a severe complication known as graft-versus-host disease (GvHD) in patients who receive bone marrow transplants.
Organoids serve as dioramas of disease, allowing UCSF scientists to understand how and why problems occur during tissue development. It's also a small step toward the creation of full-sized organs we could use for transplant.
In experiments in mice, UC San Francisco researchers have discovered that regulatory T cells, directly trigger stem cells in the skin to promote healthy hair growth.
By piercing liver cells with rapid pulses of electricity, scientists at UC San Francisco have demonstrated an entirely new way to transplant cells into organs to treat disease.
