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Judith Hellman Wins Anesthesia Award to Study Sepsis
Judith Hellman has won the 2015 Frontiers in Anesthesia Research Award to explore novel ways of understanding and combating sepsis.
In CRISPR Advance, Scientists Successfully Edit Human T Cells
In a project spearheaded by investigators at UCSF, scientists have devised a new strategy to precisely modify human T cells using the genome-editing system known as CRISPR/Cas9.
Min Cho: Blood Cell Research Grows Personal
Min Cho’s work in a UCSF lab that researches protein translational mechanisms in blood cancers was just an abstract, albeit important, concept to him – until he was diagnosed with a rare blood disease.
Age-Related Cognitive Decline Tied to Immune-System Molecule
A blood-borne molecule that increases in abundance as we age blocks regeneration of brain cells and promotes cognitive decline, suggests a new study.
Specific Roles of Adult Neural Stem Cells May Be Determined Before Birth
Adult neural stem cells, which are commonly thought of as having the ability to develop into many type of brain cells, are in reality pre-programmed before birth to make very specific types of neurons.
Cancer Blocked by Halving Levels of Protein Thought To Be ‘Untouchable’
A team of UC San Francisco and Stanford University scientists has discovered that a protein thought to be crucial for the body to develop and function correctly can be reduced by half in mice with no apparent ill effects.
The Resolution Revolution: Building a Better Microscope to See at the Atomic Level
After decades of challenges, scientists have developed an imaging technique that allows them to see the detailed structure of tiny proteins — and it's changing how we think about medicine.
Yifan Cheng, Loren Frank Among 26 New HHMI Investigators
UCSF"s Loren Frank, PhD, and Yifan Cheng, PhD, have been named Howard Hughes Medical Institute (HHMI) investigators, joining 24 other top U.S. biomedical researchers, who will receive the flexible support necessary to move their research in creative new directions.
Evolution of Stem Cells Traced in Study of Fossilized Rodent Teeth
By studying fossilized teeth from thousands of extinct rodent species, UCSF and University of Helsinki scientists have shown how fundamental evolutionary mechanisms drive the emergence of novel mammalian stem cells.
Childhood Syndrome Combining Lung Disease, Arthritis Is Identified
A research team led by scientists from UCSF, Baylor College of Medicine, and Texas Children’s Hospital has identified a new autoimmune syndrome characterized by a combination of severe lung disease and arthritis that currently has no therapy.
Angiogenesis Inhibitors Undermined by Immune Cells, Says Study
A team led by UCSF scientists has discovered a possible reason why angiogenesis inhibitors often work in the short term but usually become ineffective within months, one that could lead to a way to prevent cancer relapse.
First Look at ‘Wasabi Receptor’ Brings Insights for Pain Drug Development
Researchers at UCSF have pulled aside the curtain on a protein informally known as the “wasabi receptor,” revealing at near-atomic resolution structures that could be targeted with anti-inflammatory pain drugs.
How Beige Fat Could Fight Obesity
For the first time, scientists have isolated beige fat in adult humans that's able to convert energy-storing white fat cells into the energy-burning kind.
UMass Dartmouth, UCSF Research Demonstrates Shared Rules of Development Can Predict Patterns of Evolution in Different Species
The evolution and development of structures as diverse as limbs, fingers, teeth, somites and vertebrae may have more in common than once believed, according to a new study.