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By studying fossilized teeth from thousands of extinct rodent species, UCSF and University of Helsinki scientists have shown how fundamental evolutionary mechanisms drive the emergence of novel mammalian stem cells.
Researchers at UCSF have pulled aside the curtain on a protein informally known as the “wasabi receptor,” revealing at near-atomic resolution structures that could be targeted with anti-inflammatory pain drugs.
A research team at UC San Francisco has discovered an RNA molecule called Pnky that can be manipulated to increase the production of neurons from neural stem cells.
UCSF Magazine explores how scientists are uncovering surprising new tools – young blood and video games – to rejuvenate the brain.
A protein that may partly explain why human brains are larger than those of other animals has been identified by scientists from two stem-cell labs at UCSF.
Researchers at UC San Francisco and UC Berkeley have teamed up to create an innovative, integrated center for research on neurodegenerative diseases.
Five UCSF neuroscientists have received research grants in the highly competitive first wave of National Institutes of Health (NIH) awards to support President Obama’s BRAIN Initiative.
UCSF researchers have identified cells’ unique features within the developing human brain, using the latest technologies for analyzing gene activity in individual cells, and have demonstrated that large-scale cell surveys can be done much more efficiently and cheaply than was previously thought possible.
The immune system ages and weakens with time, making the elderly prone to life-threatening infection and other maladies, and a UCSF research team now has discovered a reason why.
A new stem-cell discovery might one day lead to a more streamlined process for obtaining stem cells, which in turn could be used in the development of replacement tissue for failing body parts.
Scientists at the Gladstone Institutes and UCSF have made an important breakthrough: they have discovered a way to transform skin cells into mature, fully functioning liver cells that flourish.
UCSF scientist Valerie Weaver, PhD, received a $1.2 million award from the California Institute for Regenerative Medicine (CIRM) for research that explores the transformation of stem cells into specialized cell types.
Geneticists from Ohio, California and Japan used stem cells to correct a defective “ring chromosome” with a normal chromosome. Such therapy has the promise to correct chromosome abnormalities that give rise to birth defects, mental disabilities and growth limitations.
In a finding that directly contradicts the standard biological model of animal cell communication, UCSF scientists have discovered that typical cells in animals have the ability to transmit and receive biological signals by making physical contact with each other, even at long distance.
Experts across UCSF weigh in on what some of 2014's top trends are in research and patient care.
