University of California San Francisco
Give to UCSF
A new UCSF study in mice has pinpointed a specific pattern of brain waves that underlies the ability to let go of old, irrelevant learned associations to make way for new updates.
UCSF researchers have become to the first to solve the structure of a hard-working protein that helps reload neurons for repeated firing.
UCSF researchers have identified a powerful self-corrective mechanism within synapses that is activated by neurodegeneration and acts to slow down disease progression in animal models of ALS.
UC San Francisco researchers have finally identified the cellular circuit responsible for conveying stress signals from inside mitochondria to the integrated stress response, a discovery that may have important implications for treating the many debilitating diseases associated with mitochondrial stress.
A new UCSF study of patients with Parkinson’s disease has revealed a pathway that transmits signals very rapidly between two parts of the human brain to govern the complex act of halting a motion once it’s been initiated.
UCSF scientists have made a significant advance toward understanding a rare genetic condition, almost exclusively affecting females, that results in a broad spectrum of neurodevelopmental deficits.
A simple blood test may soon be able to diagnose patients with two common forms of dementia – Alzheimer’s disease and frontotemporal dementia – and tell the two apart.
A blood test that may eventually be done in a doctor’s office can swiftly reveal if a patient with memory issues has Alzheimer’s disease or mild cognitive impairment and can also distinguish both conditions from frontotemporal dementia.
For a conditioned response to become long-lasting requires brain cells to increase amounts of an insulating material called myelin, which may serve to reinforce and stabilize newly formed neural connections.
Survival may more than double for adults with glioblastoma, if neurosurgeons remove the surrounding tissue as aggressively as they remove the cancerous core of the tumor.
In a study of rats navigating a simple maze, neuroscientists at UCSF have discovered how the brain may generate such imagined future scenarios. The work provides a new grounding for understanding not only how the brain makes decisions but also how imagination works more broadly, the researchers say.
Widely used organoid models fail to replicate even basic features of brain development and organization, much less the complex circuitry needed to model complex brain diseases or normal cognition.
