Digging Deeper Into Cancer
Precision Medicine Pillar No. 2: Basic Discovery. The long path to developing potent new treatments often starts with an observation in the lab that then leads to a question about a fundamental life process.
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Fast-Mutating DNA Sequences Shape Early Development; Guided Evolution of Uniquely Human Traits
Researchers at the UCSF-affiliated Gladstone Institutes have discovered how the activation of specific stretches of DNA control the development of uniquely human characteristics.
Scientists Halt Deadly Organ Tissue Scarring in its Tracks
UCSF scientists were able to arrest, and even reverse, tissue scarring of the liver, kidneys and lungs in mice. The scarring, also known as fibrosis, is a major factor in nearly half of all deaths in developed countries.
Did Inefficient Cellular Machinery Evolve to Fight Viruses and Jumping Genes?
When it comes to genes, a UCSF scientist wants to turn conventional wisdom about human and bacterial evolution on its head.
Genetic Discovery Could Help Guide Doctors’ Treatment of Bladder Cancers
A UCSF-led team of scientists has discovered that a gene mutation found in some bladder cancers is indicative of low-risk tumors that are unlikely to recur or progress after surgery.
Team Develops Targeted Therapies for Pain and Inflammation
Through support from the Catalyst Awards, UCSF researcher Aditi Bhargava is working to develop a method for delivering small-molecules to a specific target group of cells for treatment of pain.
Cell Growth Discovery Has Implications for Targeting Cancer
The way cells divide to form new cells – to support growth, to repair damaged tissues, or simply to maintain our healthy adult functioning – is controlled in previously unsuspected ways, UCSF researchers have discovered.
Childbirth Not Significant Contributor to Later Sexual Dysfunction
Childbirth is not a major contributor to sexual dysfunction in women later in life, according to a new study led by UCSF researchers.
Scientist Identifies Triple-Negative Breast Cancer Target for Drug Development
Often deadly “triple-negative” breast cancers might be effectively treated in many cases with a drug that targets a previously unknown vulnerability in the tumors, UCSF reports.
Six UCSF Researchers Win NIH Awards for High-Risk, High-Reward Work
UCSF researchers received six of 78 awards announced this week by the National Institutes of Health for innovative, high-risk, high-reward research.
Flame Retardants in Pregnant Women's Blood Drop After State Ban
A class of flame retardants that has been linked to learning difficulties in children has rapidly declined in pregnant women’s blood since the chemicals were banned in California a decade ago, according to a study led by researchers at UCSF.
UCSF Awarded $20M Federal Grant on Tobacco Regulatory Sciences
UCSF will receive a five year, $20 million grant as part of a first-of-its-kind tobacco science regulatory program by the U.S. Food and Drug Administration and the National Institutes of Health.
White Blood Cell Previously Linked to Infection May Have Another Role
A new link between meal times and daily changes in the immune system has been identified by UCSF researchers, and has led them to question assumptions about the roles of specific immune cells in infection and allergy.
Autoimmune Disease Strategy Emerges from Immune Cell Discovery
Scientists from UCSF have identified a new way to manipulate the immune system that may keep it from attacking the body’s own molecules in autoimmune diseases such as type 1 diabetes, rheumatoid arthritis and multiple sclerosis.
Tuberculosis and Parkinson’s Disease Linked By Unique Protein
A protein at the center of Parkinson’s disease research now also has been found to play a key role in causing the destruction of bacteria that cause tuberculosis.
