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Immune-Cell Population Predicts Immunotherapy Response in Melanoma

The abundance of a subtype of white blood cells in melanoma tumors can predict whether or not patients will respond to a form of cancer immunotherapy known as checkpoint blockade, according to a new study led by UCSF researchers and physicians.

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Researchers Map Zika’s Routes to the Developing Fetus

Zika virus can infect numerous cell types in the human placenta and amniotic sac, according to researchers at UCSF and UC Berkeley who show in a new paper how the virus travels from a pregnant woman to her fetus.

Zika Infection May Be Masked by Other Viral Infections

Symptoms of infection with the Zika virus in Brazil may be masked by simultaneous infection with other mosquito-spread viruses common in the same region — such as dengue fever and chikungunya viruses — pointing to the need for comprehensive testing, according to a study led by a UCSF expert in DNA-based diagnostics in collaboration with Brazilian researchers.

Covert Inflammation May Trigger Many Forms of Cancer

A previously unidentifiable type of low-grade inflammation may explain why common anti-inflammatory drugs such as aspirin have shown promise against some types of cancer – even when patients don’t display typical signs of inflammation.

Hybrid Cancer Drug Could Be Resistance-Resistant

A team of cancer researchers led by scientists at UCSF and Memorial Sloan Kettering Cancer Center in New York have developed a first-of-its-kind hybrid drug with the power to outsmart drug-resistant cancers.